Patents by Inventor Yossef Kliger

Yossef Kliger has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PVRIG POLYPEPTIDES AND METHODS OF TREATMENT
    Publication number: 20240025973
    Abstract: The present invention is directed to PVRIG polypeptides and their uses.
    Type: Application
    Filed: September 1, 2023
    Publication date: January 25, 2024
    Inventors: Mark White, Sandeep Kumar, Christopher Chan, Spencer Liang, Lance Stapleton, Andrew W. Drake, Yosi Gozlan, Ilan Vaknin, Shirley Sameah-Greenwald, Liat Dassa, Zohar Tiran, Gad S. Cojocaru, Amir Toporik, Yossef Kliger, Ofer Levy, Arthur Machlenkin, Sergey Nemzer, Yair Benita, Amit Novik
  • PVRL2 AND/OR PVRIG AS BIOMARKERS FOR TREATMENT
    Publication number: 20230400467
    Abstract: The present invention provides biomarkers for use in determining populations for treatment with anti-PVRIG antibodies and such biomarkers include, for example PVRIG and/or PVRL2 expression.
    Type: Application
    Filed: October 26, 2021
    Publication date: December 14, 2023
    Inventors: Gad S. COJOCARU, Tal Fridman KFIR, Emmanuel WEYL, Amit NOVIK, Yossef KLIGER, Niv SABATH, Eran OPHIR, Zoya ALTEBER, Masha FRENKEL
  • PVRIG polypeptides and methods of treatment
    Patent number: 11795209
    Abstract: The present invention is directed to PVRIG polypeptides and their uses.
    Type: Grant
    Filed: January 28, 2020
    Date of Patent: October 24, 2023
    Assignee: COMPUGEN LTD.
    Inventors: Mark White, Sandeep Kumar, Christopher Chan, Spencer Liang, Lance Stapleton, Andrew W. Drake, Yosi Gozlan, Ilan Vaknin, Shirley Sameah-Greenwald, Liat Dassa, Zohar Tiran, Gad S. Cojocaru, Amir Toporik, Yossef Kliger, Ofer Levy, Arthur Machlenkin, Sergey Nemzer, Yair Benita, Amit Novik
  • PVRIG POLYPEPTIDES AND METHODS OF TREATMENT
    Publication number: 20200385445
    Abstract: The present invention is directed to PVRIG polypeptides and their uses.
    Type: Application
    Filed: January 28, 2020
    Publication date: December 10, 2020
    Inventors: Mark White, Sandeep Kumar, Christopher Chan, Spencer Liang, Lance Stapleton, Andrew W. Drake, Yosi Gozlan, Ilan Vaknin, Shirley Sameah-Greenwald, Liat Dassa, Zohar Tiran, Gad S. Cojocaru, Amir Toporik, Yossef Kliger, Ofer Levy, Arthur Machlenkin, Sergey Nemzer, Yair Benita, Amit Novik
  • PVRIG polypeptides and methods of treatment
    Patent number: 10550173
    Abstract: The present invention is directed to PVRIG polypeptides and their uses.
    Type: Grant
    Filed: February 19, 2016
    Date of Patent: February 4, 2020
    Assignee: Compugen, Ltd.
    Inventors: Mark White, Sandeep Kumar, Christopher Chan, Spencer Liang, Lance Stapleton, Andrew W. Drake, Yosi Gozlan, Ilan Vaknin, Shirley Sameah-Greenwald, Liat Dassa, Zohar Tiran, Gad S. Cojocaru, Amir Toporik, Yossef Kliger, Ofer Levy, Arthur Machlenkin, Sergey Nemzer, Yair Benita, Amit Novik
  • HIDE1 COMPOSITIONS AND METHODS
    Publication number: 20180305451
    Abstract: According to at least some embodiments of the present invention is directed to anti-HIDE1 antibodies and polypeptides and methods of using same.
    Type: Application
    Filed: July 13, 2016
    Publication date: October 25, 2018
    Inventors: Yosef DICKEN, Liat DASSA, Amit NOVIK, Amir TOPORIK, Gad COJOCARU, Yossef KLIGER, Yair BENITA, Ofer LEVY, Ilan VAKNIN, Arthur MACHLENKIN, Iris HECHT, Jungmin KIM, Andrew POW, Andrew W DRAKE
  • PVRIG POLYPEPTIDES AND METHODS OF TREATMENT
    Publication number: 20170088607
    Abstract: The present invention is directed to PVRIG polypeptides and their uses.
    Type: Application
    Filed: February 19, 2016
    Publication date: March 30, 2017
    Inventors: Mark White, Sandeep Kumar, Christopher Chan, Spencer Liang, Lance Stapleton, Andrew W. Drake, Yosi Gozlan, Ilan Vaknin, Shirley Sameah-Greenwald, Liat Dassa, Zohar Tiran, Gad. S. Cojocaru, Amir Toporik, Yossef Kliger, Ofer Levy, Arthur Machlenkin, Sergey Nemzer, Yair Benita, Amit Novik
  • VSTM5 POLYPEPTIDES AND USES THEREOF AS A DRUG FOR TREATMENT OF CANCER, INFECTIOUS DISEASES AND IMMUNE RELATED DISEASES
    Publication number: 20160347814
    Abstract: This invention relates to VSTM5 proteins, soluble molecules and fusions thereof which are suitable targets for drug development and for treatment of immune related disorders, immunotherapy, treatment of cancer, infectious disorders and/or sepsis.
    Type: Application
    Filed: March 10, 2016
    Publication date: December 1, 2016
    Inventors: Zurit LEVINE, Galit ROTMAN, Liat DASSA, Ofer LEVY, Gad S. COJOCARU, Amir TOPORIK, Yossef KLIGER, Ilan VAKNIN, Iris HECHT
  • VSTM5 ANTIBODIES, AND USES THEREOF FOR TREATMENT OF CANCER, INFECTIOUS DISEASES AND IMMUNE RELATED DISEASES
    Publication number: 20160272707
    Abstract: The present invention relates to VSTM5-specific antibodies, antibody fragments, and VSTM5 polypeptides, conjugates and compositions comprising same, for modulating (antagonizing or agonizing) one or more of the effects of VSTM5 expression on immunity. More specifically, the present invention relates to VSTM5-specific antibodies, antibody fragments, and VSTM5 polypeptides, conjugates and compositions comprising same for treating and aiding in the diagnosis of cancer, infectious diseases and immune related diseases, e.g., those associated with aberrant (higher or lower than normal) VSTM5 expression by diseased and/or immune cells and/or aberrant (increased or reduced) VSTM5-mediated effects on immunity.
    Type: Application
    Filed: September 11, 2014
    Publication date: September 22, 2016
    Inventors: Zurit LEVINE, Galit ROTMAN, Liat DASSA, Ofer LEVY, Gad S. COJOCARU, Amir TOPORIK, Yossef KLIGER, Andrew POW, Spencer LIANG
  • Angiopoietin derived peptides
    Patent number: 9255132
    Abstract: Provided are angiopoietin-derived peptides or homologs or derivatives thereof, pharmaceutical composition including them, a use thereof for therapy and for the manufacture of a medicament, a method of treating a wide range of conditions, disorders and diseases therewith, nucleotide sequences encoding them, antibodies directed to epitopes thereof and fusion proteins including them.
    Type: Grant
    Filed: June 18, 2013
    Date of Patent: February 9, 2016
    Assignee: Compugen Ltd.
    Inventors: Yossef Kliger, Itamar Borukhov, Ofer Levy, Zohar Tiran, Assaf Wool, Ehud Schreiber, Anat Amir, Zurit Levine, Amir Toporik
  • BIOACTIVE PEPTIDES AND METHODS OF USING SAME
    Publication number: 20150307572
    Abstract: Disclosed are peptide ligands for G-protein coupled receptors that are useful for treating disorders associated with G-protein coupled receptor activation.
    Type: Application
    Filed: February 23, 2015
    Publication date: October 29, 2015
    Inventors: Ronen Shemesh, Zurit Levine, Amir Toporik, Chen Hermesh, Yossef Kliger, Eyal Gofer, Assaf Wool, Dvir Dahary, Yossi Cohen
  • Bioactive peptides and methods of using same
    Patent number: 8987191
    Abstract: Disclosed are peptide ligands for G-protein coupled receptors that are useful for treating disorders associated with G-protein coupled receptor activation.
    Type: Grant
    Filed: June 21, 2013
    Date of Patent: March 24, 2015
    Assignee: Compugen Ltd.
    Inventors: Ronen Shemesh, Zurit Levine, Amir Toporik, Chen Hermesh, Yossef Kliger, Eyal Gofer, Assaf Wool, Dvir Dahary, Yossi Cohen
  • BIOACTIVE PEPTIDES AND METHODS OF USING SAME
    Publication number: 20140005097
    Abstract: Disclosed are peptide ligands for G-protein coupled receptors that are useful for treating disorders associated with G-protein coupled receptor activation.
    Type: Application
    Filed: June 21, 2013
    Publication date: January 2, 2014
    Applicant: Compugen Ltd.
    Inventors: Ronen Shemesh, Zurit Levine, Amir Toporik, Chen Hermesh, Yossef Kliger, Eyal Gofer, Assaf Wool, Dvir Dahary, Yossi Cohen
  • ANGIOPOIETIN DERIVED PEPTIDES
    Publication number: 20140004175
    Abstract: Provided are angiopoietin-derived peptides or homologs or derivatives thereof, pharmaceutical composition including them, a use thereof for therapy and for the manufacture of a medicament, a method of treating a wide range of conditions, disorders and diseases therewith, nucleotide sequences encoding them, antibodies directed to epitopes thereof and fusion proteins including them.
    Type: Application
    Filed: June 18, 2013
    Publication date: January 2, 2014
    Applicant: Compugen Ltd.
    Inventors: Yossef KLIGER, Itamar Borukhov, Ofer Levy, Zohar Tiran, Assaf Wool, Ehud Schreiber, Anat Amir, Zurit Levine, Amir Toporik
  • Clusterin derived peptide
    Patent number: 8575107
    Abstract: Clusterin-derived peptides or homologues or derivatives thereof, pharmaceutical compositions including the same, methods of manufacturing the peptides, homologues, derivatives thereof and compositions including the same, and methods of treating conditions including administering the peptides, homologues, derivatives thereof and compositions including the same, are provided. Also provided are nucleotide sequences encoding the peptides, homologues, derivatives thereof and compositions including the same, antibodies directed to epitopes thereof and fusion proteins including the same.
    Type: Grant
    Filed: January 22, 2009
    Date of Patent: November 5, 2013
    Assignee: Compugen Ltd.
    Inventors: Yossef Kliger, Ofer Levy, Itamar Borukhov, Assaf Wool, Ehud Schreiber, Anat Amir, Zurit Levine, Zohar Tiran, Anat Oren, Amir Toporik
  • Angiopoietin derived peptides
    Patent number: 8529943
    Abstract: Provided are angiopoietin-derived peptides or homologs or derivatives thereof, pharmaceutical composition including them, a use thereof for therapy and for the manufacture of a medicament, a method of treating a wide range of conditions, disorders and diseases therewith, nucleotide sequences encoding them, antibodies directed to epitopes thereof and fusion proteins including them.
    Type: Grant
    Filed: July 20, 2009
    Date of Patent: September 10, 2013
    Assignee: Compugen Ltd.
    Inventors: Yossef Kliger, Itamar Borukhov, Ofer Levy, Zohar Tiran, Assaf Wool, Ehud Schreiber, Anat Amir, Zurit Levine, Amir Toporik
  • GP96 derived peptides
    Patent number: 8512708
    Abstract: Provided is a gp96-derived peptides or homologs or derivatives thereof, pharmaceutical composition including them, a use thereof for therapy and for the manufacture of a medicament, a method of treating a wide range of conditions, disorders and diseases therewith, nucleotide sequences encoding them, antibodies directed to epitopes thereof and fusion proteins including them.
    Type: Grant
    Filed: March 12, 2009
    Date of Patent: August 20, 2013
    Assignee: Compugen Ltd.
    Inventors: Yossef Kliger, Ofer Levy, Itamar Borukhov, Anat Amir, Anat Oren
  • ANGIOPOIETIN DERIVED PEPTIDES
    Publication number: 20110206760
    Abstract: Provided are angiopoietin-derived peptides or homologs or derivatives thereof, pharmaceutical composition including them, a use thereof for therapy and for the manufacture of a medicament, a method of treating a wide range of conditions, disorders and diseases therewith, nucleotide sequences encoding them, antibodies directed to epitopes thereof and fusion proteins including them.
    Type: Application
    Filed: July 20, 2009
    Publication date: August 25, 2011
    Applicant: COMPUGEN LTD.
    Inventors: Yossef Kliger, Itamar Borukhov, Ofer Levy, Zohar Tiran, Assaf Wool, Ehud Schreiber, Anat Amir, Zurit Levine, Amir Toporik
  • NOVEL GP96 DERIVED PEPTIDES
    Publication number: 20110189188
    Abstract: Provided is a gp96-derived peptides or homologs or derivatives thereof, pharmaceutical composition including them, a use thereof for therapy and for the manufacture of a medicament, a method of treating a wide range of conditions, disorders and diseases therewith, nucleotide sequences encoding them, antibodies directed to epitopes thereof and fusion proteins including them.
    Type: Application
    Filed: March 12, 2009
    Publication date: August 4, 2011
    Applicant: COMPUGEN LTD.
    Inventors: Yossef Kliger, Ofer Levy, Itamar Borukhov, Anat Amir, Anat Oren
  • BIOACTIVE PEPTIDES AND METHODS OF USING SAME
    Publication number: 20110177998
    Abstract: Disclosed are peptide ligands for G-protein coupled receptors that are useful for treating disorders associated with G-protein coupled receptor activation.
    Type: Application
    Filed: July 11, 2008
    Publication date: July 21, 2011
    Inventors: Ronen Shemesh, Zurit Levine, Amir Toporik, Chen Hermesh, Yossef Kliger, Eyal Gofer, Assaf Wool, Dvir Dahary, Yossi Cohen