Patents by Inventor Yotaro Fujita
Yotaro Fujita has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 9713657Abstract: A catheter balloon exhibiting improved pressure resistance of the entire membrane is formed of a membrane as a laminate of at least two layers including a polyamide elastomer layer and a polyamide layer, in which the polyamide elastomer layer is disposed at the inner side of the polyamide layer, a refractive index nr1 in the circumferential direction of a cross-section perpendicular to the axis in the inner side surface of the polyamide layer is greater than a refractive index nr2 in the circumferential direction of a cross-section perpendicular to the axis in the inner side surface of the polyamide elastomer layer, and the difference between the refractive index nr1 and the refractive index nr2 is 0.01 or greater.Type: GrantFiled: March 21, 2014Date of Patent: July 25, 2017Assignee: TERUMO KABUSHIKI KAISHAInventors: Yotaro Fujita, Makoto Onishi, Naoyuki Maeda
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Patent number: 9457170Abstract: A balloon including a laminated film of at least two layers including a polyamide elastomer layer and a polyamide layer wherein the polyamide elastomer layer is formed at the inner side of the polyamide layer and a molecular weight distribution of the polymers as a whole of the balloon (weight-average molecular weight MW/number-average molecular weight Mn) ranges from 3 to 10.Type: GrantFiled: December 31, 2012Date of Patent: October 4, 2016Assignee: TERUMO KABUSHIKI KAISHAInventors: Yotaro Fujita, Makoto Onishi, Naoyuki Maeda
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Patent number: 8835570Abstract: A hydrophilic material having a hydrophilic nature and being biocompatible and processable into nanoparticles wherein a hydrophilic monomer such as threitol or a hydrophilic polymer such as polyethylene glycol is attached to the ?position of an ?,?-unsaturated carboxyl group of a (co)polymer comprising an aromatic compound such as 4-hydroxycinnamic acid in which an aromatic ring is substituted by the ?,?-unsaturated carboxyl group and one or more hydroxyl groups. In particular, a hydrophilic material having a nanoparticle size which is highly dispersible in water, can well migrate into the blood and is useful as a drug carrier, a medical material and a sustained drug release material.Type: GrantFiled: September 29, 2009Date of Patent: September 16, 2014Assignees: Osaka University, Terumo Kabushiki KaishaInventors: Mitsuru Akashi, Michiya Matsusaki, Dongjian Shi, Makoto Onishi, Yotaro Fujita
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Publication number: 20140207171Abstract: A catheter balloon exhibiting improved pressure resistance of the entire membrane is formed of a membrane as a laminate of at least two layers including a polyamide elastomer layer and a polyamide layer, in which the polyamide elastomer layer is disposed at the inner side of the polyamide layer, a refractive index nr1 in the circumferential direction of a cross-section perpendicular to the axis in the inner side surface of the polyamide layer is greater than a refractive index nr2 in the circumferential direction of a cross-section perpendicular to the axis in the inner side surface of the polyamide elastomer layer, and the difference between the refractive index nr1 and the refractive index nr2 is 0.01 or greater.Type: ApplicationFiled: March 21, 2014Publication date: July 24, 2014Applicant: TERUMO KABUSHIKI KAISHAInventors: Yotaro FUJITA, Makoto ONISHI, Naoyuki MAEDA
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Publication number: 20120296415Abstract: A bioabsorbable stent has a relatively high radial force and can be placed directly at the lesion without the possibility or reducing the possibility of occluding the lesion again after placement. The bioabsorbable stent is formed from a mixture composed of a bioabsorbable aliphatic polyester and an aromatic compound having one or more aromatic rings.Type: ApplicationFiled: July 31, 2012Publication date: November 22, 2012Applicant: TERUMO KABUSHIKI KAISHAInventors: Yotaro Fujita, Makoto Onishi
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Patent number: 8222349Abstract: A bioabsorbable material which is flexible and degradable at a controlled rate, and an in-vivo indwelling device made thereof. The bioabsorbable material is a copolymer composed of an aromatic compound having an ?,?-unsaturated carboxylic group and at least one hydroxyl group as substituents on the aromatic ring, and a polycarbonate or a monomer constituting polycarbonate. Alternatively, it is a copolymer composed of, as the first component, an aromatic compound having an ?,?-unsaturated carboxylic group and at least one hydroxyl group as substituents on the aromatic ring, as the second component, an aromatic compound having an ?,?-unsaturated carboxylic group and at least two hydroxyl groups as substituents on the aromatic ring, and, as the third component, a polycarbonate or a monomer constituting polycarbonate.Type: GrantFiled: September 21, 2010Date of Patent: July 17, 2012Assignee: Terumo Kabushiki KaishaInventors: Mitsuru Akashi, Michiya Matsusaki, Yotaro Fujita, Makoto Onishi
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Publication number: 20110257338Abstract: A hydrophilic material having a hydrophilic nature and being biocompatible and processable into nanoparticles wherein a hydrophilic monomer such as threitol or a hydrophilic polymer such as polyethylene glycol is attached to the ?position of an ?, ?-unsaturated carboxyl group of a (co)polymer comprising an aromatic compound such as 4-hydroxycinnamic acid in which an aromatic ring is substituted by the ?, ?-unsaturated carboxyl group and one or more hydroxyl groups. In particular, a hydrophilic material having a nanoparticle size which is highly dispersible in water, can well migrate into the blood and is useful as a drug carrier, a medical material and a sustained drug release material.Type: ApplicationFiled: September 29, 2009Publication date: October 20, 2011Applicants: TERUMO KABUSHIKI KAISHA, OSAKA UNIVERSITYInventors: Mitsuru Akashi, Michiya Matsusaki, Dongjian Shi, Makoto Onishi, Yotaro Fujita
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Publication number: 20110046309Abstract: A bioabsorbable material which is flexible and degradable at a controlled rate, and an in-vivo indwelling device made thereof. The bioabsorbable material is a copolymer composed of an aromatic compound having an ?,?-unsaturated carboxylic group and at least one hydroxyl group as substituents on the aromatic ring, and a polycarbonate or a monomer constituting polycarbonate. Alternatively, it is a copolymer composed of, as the first component, an aromatic compound having an ?,?-unsaturated carboxylic group and at least one hydroxyl group as substituents on the aromatic ring, as the second component, an aromatic compound having an ?,?-unsaturated carboxylic group and at least two hydroxyl groups as substituents on the aromatic ring, and, as the third component, a polycarbonate or a monomer constituting polycarbonate.Type: ApplicationFiled: September 21, 2010Publication date: February 24, 2011Applicant: Terumo Kabushiki KaishaInventors: Mitsuru Akashi, Michiya Matsusaki, Yotaro Fujita, Makoto Onishi
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Publication number: 20080275547Abstract: An intravascular, indwelling instrument for placement in a blood vessel includes a body having a face in contact with a maintained blood flow to be maintained and a face in contact with a non-maintained blood flow not to be maintained, and a peptide fixed to all or part of the maintained blood flow contact face or the non-maintained blood flow contact face of the body. The peptide has specific interaction with vascular endothelial precursor cells, with the peptide permitting selective adsorption and adhesion of the vascular endothelial precursor cells to cover all or part of the maintained blood flow contact face or the non-maintained blood flow contact face of the body with the vascular endothelial precursor cells thereby reducing or inhibiting the blood flow not to be maintained.Type: ApplicationFiled: July 3, 2008Publication date: November 6, 2008Applicant: Terumo Kabushiki KaishaInventors: Takeshi KANAMARU, Yotaro Fujita
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Publication number: 20060052862Abstract: An intravascular, indwelling instrument for placement in a blood vessel includes a body having a face in contact with a maintained blood flow to be maintained and a face in contact with a non-maintained blood flow not to be maintained, and a peptide fixed to all or part of the maintained blood flow contact face or the non-maintained blood flow contact face of the body. The peptide has specific interaction with vascular endothelial precursor cells, with the peptide permitting selective adsorption and adhesion of the vascular endothelial precursor cells to cover all or part of the maintained blood flow contact face or the non-maintained blood flow contact face of the body with the vascular endothelial precursor cells thereby reducing or inhibiting the blood flow not to be maintained.Type: ApplicationFiled: September 2, 2005Publication date: March 9, 2006Applicant: Terumo Kabushiki KaishaInventors: Takeshi Kanamaru, Yotaro Fujita