Patents by Inventor Young Dok Son

Young Dok Son has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • FUSION POLYPEPTIDE COMPRISING GDF15 AND POLYPEPTIDE REGION CAPABLE OF O-GLYCOSYLATION
    Publication number: 20230133672
    Abstract: Disclosed are: a fusion polypeptide comprising growth differentiation factor 15 (GDF15) and a polypeptide region capable of O-glycosylation; a pharmaceutical composition comprising the fusion polypeptide; and a method for increasing the in vivo duration of GDF15, comprising the step of fusing a polypeptide region capable of O-glycosylation.
    Type: Application
    Filed: December 10, 2020
    Publication date: May 4, 2023
    Applicant: LG CHEM, LTD.
    Inventors: Yeonchul KIM, Young Dok SON, Kyubong NA, Ji Ho HONG, Saem JUNG, Myung Won JIN, Ji A PARK, Soomin NOH, Hyuntaek PARK
  • FUSION POLYPEPTIDE COMPRISING Fc REGION OF IMMUNOGLOBULIN AND GDF15
    Publication number: 20230053119
    Abstract: Provided is a fusion polypeptide comprising GDF15 (Growth/differentiation factor 15) and an Fc region of immunoglobulin, a pharmaceutical composition comprising the fusion polypeptide, and a method of increasing in vivo duration of GDF15 comprising fusing with an Fc region of immunoglobulin.
    Type: Application
    Filed: April 22, 2020
    Publication date: February 16, 2023
    Applicant: LG CHEM, LTD.
    Inventors: Yeonchul KIM, Kyeongsik MIN, Young Dok SON, Kyubong NA, Ji Ho HONG, Saem JUNG, Myung Won JIN, Ji A PARK, Soomin NOH
  • FUSION POLYPEPTIDE COMPRISING POLYPEPTIDE REGION THAT CAN BE O-GLYCOSYLATED
    Publication number: 20210340281
    Abstract: Disclosed are a fusion polypeptide comprising a target polypeptide and a hinge region of an immunoglobulin; a pharmaceutical composition containing the fusion polypeptide; and a method for increasing the in vivo period of a target polypeptide, comprising a step of fusing a hinge region of an immunoglobulin with the target polypeptide.
    Type: Application
    Filed: September 4, 2019
    Publication date: November 4, 2021
    Applicant: LG CHEM, LTD.
    Inventors: Yeonchul KIM, Seung Joo LEE, Jong Uk KOH, Kyuyong KIM, Saem JUNG, Young Dok SON
  • Method for preparing recombinant glycoproteins with high sialic acid content
    Patent number: 8940876
    Abstract: The present disclosure relates to a method for preparing recombinant glycoproteins with high sialic acid content. More specifically, for UDP-GlcNAc 2-epimerase/ManNAc kinase (GNE/MNK) enzyme where point mutation was induced by substituting arginine at position 263 by leucine only or by further substituting arginine at position 266 by glutamine, epimerase activity is constantly maintained, and overexpressed cells thereof experience an increase in intracellular cytidine monophosphate (CMP)-sialic acid content, irrespective of CMP-sialic acid concentration.
    Type: Grant
    Filed: February 1, 2011
    Date of Patent: January 27, 2015
    Assignee: Korea Advanced Institute of Science and Technology
    Inventors: Jung Hoe Kim, Young Dok Son, Jin Young Hwang, Yeon Tae Jeong
  • Glycoprotein Analysis Kit and Use Thereof
    Publication number: 20130203617
    Abstract: Disclosed are a glycoprotein analysis kit and use thereof. The glycoprotein analysis kit comprises a fluorescently labeled antibody, a fluorescently labeled biomaterial, and a support, and is used in a dual probing method for analyzing the content of a glycoprotein and profiling the oligosaccharide chain, simultaneously, and a method for selecting a single cell producing the glycoprotein having a desired glycosylation pattern. Also, a single cell producing the glycoprotein having a desired glycosylation pattern is provided.
    Type: Application
    Filed: April 29, 2011
    Publication date: August 8, 2013
    Applicant: KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Hak Sung Kim, Sun Young Park, Sang Chul Lee, Eun Kyoung Kim, Sung Ho Kim, Wan Jung Kim, Yong Tae Kim, Young Dok Son, Jung Hoe Kim
  • METHOD FOR PREPARING RECOMBINANT GLYCOPROTEINS WITH HIGH SIALIC ACID CONTENT
    Publication number: 20120149874
    Abstract: The present disclosure relates to a method for preparing recombinant glycoproteins with high sialic acid content. More specifically, for UDP-GlcNAc 2-epimerase/ManNAc kinase (GNE/MNK) enzyme where point mutation was induced by substituting arginine at position 263 by leucine only or by further substituting arginine at position 266 by glutamine, epimerase activity is constantly maintained, and overexpressed cells thereof experience an increase in intracellular cytidine monophosphate (CMP)-sialic acid content, irrespective of CMP-sialic acid concentration.
    Type: Application
    Filed: February 1, 2011
    Publication date: June 14, 2012
    Applicant: KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Jung Hoe Kim, Young Dok Son, Jin Young Hwang, Yeon Tae Jeong