Abstract: A method of preparing polylactic acid (PLA) microsphere and polylactic-co-glycolic acid (PLGA) microsphere is provided, including the following steps. A first solution is provided, including polylactic acid or polylactic-co-glycolic acid and an organic solvent. A second solution is provided, including polyvinyl alcohol, sodium carboxymethyl cellulose and an aqueous solution. The first solution is added to the second solution and, at the same time, the second solution is agitated until polylactic acid is solidified to form a plurality of polylactic acid microspheres, or until polylactic-co-glycolic acid is solidified to form a plurality of polylactic-co-glycolic acid microspheres. The polylactic acid microspheres or polylactic-co-glycolic acid microspheres are collected.

Abstract: A method of preparing polylactic acid (PLA) microsphere and polylactic-co-glycolic acid (PLGA) microsphere is provided, including the following steps. A first solution is provided, including polylactic acid or polylactic-co-glycolic acid and an organic solvent. A second solution is provided, including polyvinyl alcohol, sodium carboxymethyl cellulose and an aqueous solution. The first solution is added to the second solution and, at the same time, the second solution is agitated until polylactic acid is solidified to form a plurality of polylactic acid microspheres, or until polylactic-co-glycolic acid is solidified to form a plurality of polylactic-co-glycolic acid microspheres. The polylactic acid microspheres or polylactic-co-glycolic acid microspheres are collected.

Abstract: A method of preparing polylactic acid (PLA) microsphere and polylactic-co-glycolic acid (PLGA) microsphere is provided, including the following steps. A first solution is provided, including polylactic acid or polylactic-co-glycolic acid and an organic solvent. A second solution is provided, including polyvinyl alcohol, sodium carboxymethyl cellulose and an aqueous solution. The first solution is added to the second solution and, at the same time, the second solution is agitated until polylactic acid is solidified to form a plurality of polylactic acid microspheres, or until polylactic-co-glycolic acid is solidified to form a plurality of polylactic-co-glycolic acid microspheres. The polylactic acid microspheres or polylactic-co-glycolic acid microspheres are collected.

Abstract: A nebulizer with a negative pressure structure includes a nebulization body, a carrying cavity, a nebulizing element and a negative pressure generating element. The carrying cavity is provided for carrying a nebulized liquid and has a through hole. The nebulizing element is installed at the through hole and includes a piezoelectric driving unit and a nebulizing plate disposed on a side of the piezoelectric driving unit. The negative pressure generating element is formed on the carrying cavity and provided for changing the volume of the carrying cavity or removing air from the carrying cavity to reduce the air pressure in the carrying cavity, so as to nebulize a liquid of low surface tension or high viscosity effectively.

Abstract: High drug load pharmaceutical compositions and production methods thereof are provided. The pharmaceutical composition includes at least one viscous active pharmaceutical ingredient or a pharmaceutically acceptable salts thereof. The at least one viscous active pharmaceutical ingredient accounts for at least 60% by weight of the total solid weight of the pharmaceutical composition. The saturated solution of the at least one viscous active pharmaceutical ingredient has a viscosity of at least 20 centipoises at 25° C. Alternatively, the aqueous solution of the at least one viscous active pharmaceutical ingredient with a concentration lower than 55 wt % has at least a viscosity of at least 10 centipoises at 25° C.

Abstract: Disclosed is a rotary nebulization device installed to a container that contains a liquid to be nebulized, and the rotary nebulization device includes a main body, an electric connection ring, an nebulization ring and a rotary ring. The main body contains a power supply, the electric connection ring, the nebulization ring and the rotary ring sequentially installed on a side of the main body, and the electric connection ring has a first contact electrically coupled to the power supply, and the nebulization ring has an nebulization module electrically coupled to the first contact, and the rotary ring has a second contact corresponding to the first contact. The corresponding container has an opening portion and a liquid storage slot, and the rotary ring is provided for switching the connection and electric conduction between the liquid storage slot and the nebulization module to improve the convenience of operation.

Abstract: Disclosed is a constant quantity control nebulization device including a main body, a nebulization module, a fixing plate and a rotary ring, and the device is installed to a container that contains a liquid to be nebulized. A first liquid storage space with a predetermined volume is defined at the top of the main body, and the nebulization module is installed in the main body and interconnected to the first liquid storage space, and the fixing plate is fixed onto the main body and has a first through hole, the rotary ring is sheathed on the top of the main body and axially coupled to the fixing plate, and the rotary ring has a second through hole corresponding to the first through hole. The consumption of the liquid to be nebulized can be controlled by rotating the rotary ring to improve the convenience of operation significantly.

Abstract: An efficiency enhancing device for replaceable cosmetic skincare pads includes a main body with a containing space, a motor installed in the main body, a driving platform installed at the top end of the main body and electrically connected to the motor and having first ribs on a surface of the driving platform, a propping platform installed at a position corresponding to the driving platform and having bumps formed on a side corresponding to the first ribs, such that the driving platform can be driven by the motor to drive the propping platform to move up and down, and a carrying platform disposed above the propping platform for installing the skincare pad. The carrying platform moves up and down by the propping platform and the driving platform to touch a user's skin.

Abstract: Disclosed is a rotary nebulization device installed to a container that contains a liquid to be nebulized, and the rotary nebulization device includes a main body, an electric connection ring, an nebulization ring and a rotary ring. The main body contains a power supply, the electric connection ring, the nebulization ring and the rotary ring sequentially installed on a side of the main body, and the electric connection ring has a first contact electrically coupled to the power supply, and the nebulization ring has an nebulization module electrically coupled to the first contact, and the rotary ring has a second contact corresponding to the first contact. The corresponding container has an opening portion and a liquid storage slot, and the rotary ring is provided for switching the connection and electric conduction between the liquid storage slot and the nebulization module to improve the convenience of operation.

Abstract: Disclosed is a constant quantity control nebulization device including a main body, a nebulization module, a fixing plate and a rotary ring, and the device is installed to a container that contains a liquid to be nebulized. A first liquid storage space with a predetermined volume is defined at the top of the main body, and the nebulization module is installed in the main body and interconnected to the first liquid storage space, and the fixing plate is fixed onto the main body and has a first through hole, the rotary ring is sheathed on the top of the main body and axially coupled to the fixing plate, and the rotary ring has a second through hole corresponding to the first through hole. The consumption of the liquid to be nebulized can be controlled by rotating the rotary ring to improve the convenience of operation significantly.