Patents by Inventor Yu Ying Lin
Yu Ying Lin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20160130336Abstract: An anti-VEGF antibody, or a binding fragment thereof, includes a heavy-chain variable region that comprises: (1) a CDRH1 sequence selected from SEQ ID NO: 17, 20, 23, 26, 29, 32, 35, or 38), (2) a CDRH2 sequence selected from SEQ ID NO:18, 21, 24, 27, 30, 33, 36, or 39, and (3) a CDRH3 sequence selected from SEQ ID NO:19, 22, 25, 28, 31, 34, 37, or 40; and a light-chain variable region that comprises: (1) a CDRL1 sequence selected from SEQ ID NO: 41, 44, 47, 50, 53, 56, 59, or 62, (2) a CDRL2 sequence selected from SEQ ID NO: 42, 45, 48, 51, 54, 57, 60, or 63, and (3) a CDRL3 sequence selected from SEQ ID NO: 43, 46, 49, 52, 55, 58, 61, or 64. A method for treating or preventing a VEGF-related disorder, e.g., diabetic retinopathy, age-related macular degeneration, or cancer, uses the antibodies.Type: ApplicationFiled: December 29, 2014Publication date: May 12, 2016Applicants: Development Center for Biotechnology, DCB-USA LLCInventors: Jiann-Shiun Lai, Yan-Da Lai, Yen-Yu Wu, Yi-Jiue Tsai, Yu-Ying Lin
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Publication number: 20160119461Abstract: A wearable electronic device performs a voice communication through a host. The wearable electronic device includes a wireless transmission module, an identification module and a voice transceiver module. The wireless transmission module is configured to transmit signals with the host. The identification module is stored with a prepaid amount data provided to the host for a validation, and the wearable electronic device builds up a voice communication through the host when the validation is positive. The voice transceiver module is electrically connected to the wireless transmission module. A telephone apparatus using the aforementioned wearable electronic device is also provided.Type: ApplicationFiled: December 30, 2014Publication date: April 28, 2016Inventors: SHENG-LIAN LIN, YU-YING LIN, TUNG-YI LIN
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Publication number: 20160113210Abstract: A planting package is provided. The planting package includes a water discharging bag, a soil, at least a seed and a hanging structure, wherein the water discharging bag is made of material having water discharging function. The water discharging bag has a tear line to form a tear portion on the water discharging bag. The soil is disposed in the water discharging bag, the seed is also disposed in the water discharging bag, and the hanging structure is disposed on an outer surface of the water discharging bag. The planting package has the advantage of easily planted.Type: ApplicationFiled: December 4, 2014Publication date: April 28, 2016Inventors: SHENG-LIAN LIN, YU-YING LIN, TUNG-YI LIN
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Publication number: 20160115944Abstract: A driving device includes a hub portion, a plurality of extension plates and a plurality of driving components. Each extension plate has a first terminal and a second terminal opposite to each other. The first terminal of each extension plate is connected to the hub portion. Each driving component is movably disposed in the respective extension plate. When a first of the plurality of driving component moves along a straight direction, a second of the plurality of driving component moves along a curved direction, thereby resulting in that the first and second driving components corporately drive the hub portion to rotate along a direction, wherein the first and second driving components are disposed opposite to each other.Type: ApplicationFiled: December 24, 2014Publication date: April 28, 2016Inventors: SHENG-LIAN LIN, YU-YING LIN, TUNG-YI LIN
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Publication number: 20160068595Abstract: A humanized antibody, or a scFv, Fab, or F(ab?)2 thereof, includes: a heavy chain variable region, or a homologous variant thereof, wherein the heavy chain variable region includes: heavy chain framework regions, CDRH1 that has the sequence of SEQ ID NO:19, CDRH2 that has the sequence of SEQ ID NO:20, and CDRH3 that has the sequence of SEQ ID NO:21, wherein the heavy chain variable region and the homologous variant share at least 90% sequence identity in the heavy chain framework regions; and a light chain variable region, or a homologous variant thereof, that includes: light chain framework regions, CDRL1 that has the sequence of SEQ ID NO:22, CDRL2 that has the sequences of SEQ ID NO:23, and CDRL3 that has the sequences of SEQ ID NO:24, wherein the light chain variable region and the homologous variant share at least 90% sequence identity in the light chain framework regions.Type: ApplicationFiled: April 18, 2014Publication date: March 10, 2016Applicants: Development Center for Biotechnology, DCB-USA LLCInventors: Chia-Cheng Wu, Chao-Yang Huang, Yu-Ying Lin, Yu-Jung Chen, Jiann-Shiun Lai
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Patent number: 9279820Abstract: A method for manipulating a droplet by a droplet manipulating device including a flow channel, a first magnetic field generator, and a second magnetic field generator is provided. The first magnetic field generator includes two first magnetic field modules and are at two sides of the flow channel. The second magnetic field generator is between the two first magnetic field modules and includes multiple second magnetic field coils. The droplet is provided in the flow channel and includes a magnetic particle. A first magnetic field is produced on the flow channel by the first magnetic field modules, so the magnetic particle in the droplet has the direction of magnetic field corresponding to the first magnetic field. A second magnetic field is produced on the flow channel by the second magnetic field coils, for driving the magnetic particle in the droplet to be in motion in the flow channel.Type: GrantFiled: May 7, 2015Date of Patent: March 8, 2016Assignee: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTEInventors: Shao-Hsing Yeh, Yu-Ying Lin, Chi-Han Chiou, Liang-Ju Chien
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Patent number: 9274131Abstract: The disclosure relates to a droplet manipulating device and a method for manipulating a droplet. The droplets manipulating device includes a first magnetic field generator, a second magnetic field generator, and a flow channel. The first magnetic field generator produces a first magnetic field on the droplet, so that the droplet has the direction of magnetic field corresponding to the first magnetic field. Further, the second magnetic field generator produces a second magnetic field on the droplet so as to drive the droplet to be in motion in the flow channel.Type: GrantFiled: June 2, 2014Date of Patent: March 1, 2016Assignee: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTEInventors: Shao-Hsing Yeh, Yu-Ying Lin, Chi-Han Chiou, Liang-Ju Chien
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Publication number: 20150233954Abstract: A method for manipulating a droplet by a droplet manipulating device including a flow channel, a first magnetic field generator, and a second magnetic field generator is provided. The first magnetic field generator includes two first magnetic field modules and are at two sides of the flow channel. The second magnetic field generator is between the two first magnetic field modules and includes multiple second magnetic field coils. The droplet is provided in the flow channel and includes a magnetic particle. A first magnetic field is produced on the flow channel by the first magnetic field modules, so the magnetic particle in the droplet has the direction of magnetic field corresponding to the first magnetic field. A second magnetic field is produced on the flow channel by the second magnetic field coils, for driving the magnetic particle in the droplet to be in motion in the flow channel.Type: ApplicationFiled: May 7, 2015Publication date: August 20, 2015Inventors: Shao-Hsing YEH, Yu-Ying LIN, Chi-Han CHIOU, Liang-Ju CHIEN
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Publication number: 20150027554Abstract: The disclosure relates to a droplet manipulating device and a method for manipulating a droplet. The droplets manipulating device includes a first magnetic field generator, a second magnetic field generator, and a flow channel. The first magnetic field generator produces a first magnetic field on the droplet, so that the droplet has the direction of magnetic field corresponding to the first magnetic field. Further, the second magnetic field generator produces a second magnetic field on the droplet so as to drive the droplet to be in motion in the flow channel.Type: ApplicationFiled: June 2, 2014Publication date: January 29, 2015Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTEInventors: Shao-Hsing YEH, Yu-Ying LIN, Chi-Han CHIOU, Liang-Ju CHIEN
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Publication number: 20150029491Abstract: A apparatus for microfluid detection for detecting a sample fluid including a plurality of magnetic particles is provided. The apparatus for microfluid detection includes a microfluidic chip and a magnetic generating module. The microfluidic chip includes a substrate and microfluidic channels, wherein the sample fluid is carried by a carry surface of the substrate. The magnetic generating module is adapted for providing a positioning magnetic field and a surrounding magnetic field. The magnetic module controls to move the sample fluid and change a distribution of the magnetic particles in the sample fluid through the positioning magnetic field and the surrounding magnetic field.Type: ApplicationFiled: March 21, 2014Publication date: January 29, 2015Applicant: Industrial Technology Research InstituteInventors: Liang-Ju Chien, Chi-Han Chiou, Shao-Hsing Yeh, Yu-Ying Lin
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Publication number: 20150011438Abstract: A detection chip is provided. The detection chip includes a substrate, an active reagent, a hydrophilic droplet and a lipophilic substance. The substrate includes a first containing slot, wherein the first containing slot includes a first space and a second space adjacent to each other. The active reagent is disposed in the first space of the first containing slot. The hydrophilic droplet is disposed in the second space of the first containing slot. The lipophilic substance is disposed in the first containing slot, wherein the lipophilic substance is immiscible to the active reagent and the hydrophilic droplet, and separates the active reagent from the hydrophilic droplet.Type: ApplicationFiled: March 21, 2014Publication date: January 8, 2015Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTEInventors: Liang-Ju Chien, Yu-Ying Lin, Chi-Han Chiou
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Publication number: 20140314741Abstract: FLB5M5 is a humanized monoclonal antibody with three mutated amino acids in the CDRs relative to its parental mouse anti-IL-20 monoclonal antibody 7E and five mutated amino acids of the light-chain framework region relative to the amino acids of the light-chain framework region of human V?2. FLB5M5 not only retains binding specificity toward IL-20 but also has a better binding affinity than 7E for IL-20. FLB5M5 is also less immunogenic than 7E to the human host in clinical application. A mutation in the light chain CDR to tyrosine increases binding affinity to IL-20. A method for treating rheumatoid arthritis using FLB5M5 is also disclosed.Type: ApplicationFiled: April 18, 2013Publication date: October 23, 2014Applicant: DEVELOPMEN CENTER FOR BIOTECHNOLOGYInventors: CHIA-CHENG WU, CHAO-YANG HUANG, YU-YING LIN, YU-JUNG CHEN, JIANN-SHIUN LAI
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Publication number: 20140266083Abstract: An energy-saving device is electrically connected between an output terminal of an electric power and an input terminal of a load and includes a current dividing unit connected with the load in parallel, and a voltage dividing unit connected with the load serially. The current dividing unit has an input terminal electrically coupled to an output terminal of the load and an output terminal electrically coupled to the input terminal of the load. The voltage dividing unit has an input terminal electrically coupled to the output terminal of the electric power and an output terminal electrically coupled to the input terminal of the load. Thus, the voltage dividing unit drops the voltage of the load applied by the electric power, and the current dividing unit increases the current flowing into the load, so that the energy-saving device achieves an energy-saving purpose.Type: ApplicationFiled: March 13, 2013Publication date: September 18, 2014Inventors: Sheng-Lian Lin, Yu-Ying Lin, Tung-Yi Lin
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Patent number: 8035960Abstract: A hard disk drive frame is provided. The distances from its hard disk drive fixing parts to the substrate center are not the same. During the process of vibrational energy transfer, three-dimensional reactions are induced correspondingly to cancel the kinetic energy transfer. The reactions generated at the static balance point in the three dimensions interfere one another to destroy vibrational frequencies in specific directions. Therefore, the disclosed hard disk drive is resistant to vibrations and suffers less from the resonance effect.Type: GrantFiled: November 24, 2009Date of Patent: October 11, 2011Assignee: Moxa Inc.Inventor: Yu Ying Lin
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Publication number: 20110122757Abstract: A hard disk drive frame is provided. The distances from its hard disk drive fixing parts to the substrate center are not the same. During the process of vibrational energy transfer, three-dimensional reactions are induced correspondingly to cancel the kinetic energy transfer. The reactions generated at the static balance point in the three dimensions interfere one another to destroy vibrational frequencies in specific directions. Therefore, the disclosed hard disk drive is resistant to vibrations and suffers less from the resonance effect.Type: ApplicationFiled: November 24, 2009Publication date: May 26, 2011Applicant: MOXA INC.Inventor: Yu Ying Lin
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Patent number: D397753Type: GrantFiled: April 8, 1996Date of Patent: September 1, 1998Inventor: Liao Yu-Ying Lin