Abstract: A VEGF inhibitor is used in preparation of a medicament for treating hypoxia-related diseases. The VEGF inhibitor can significantly inhibit VEGF stress expression caused by hypoxia by acting on a binding pathway of VEGF and a VEGF receptor, is used for treating hypoxia and other related diseases, can significantly improve the oxygenation index of a patient, and can alleviate the hypoxic state of lung and other organ tissues, having good therapeutic effects.

Abstract: A method and an apparatus for quantizing an activation volume of a deep neural network are disclosed. The method includes: obtaining an activation volume of a network layer in the deep neural network (S101), wherein elements in the activation volume are arranged in three directions: height, width, and depth; dividing depth segments in the activation volume in which a difference among element features is smaller than a preset threshold into a same slice group along the depth direction of the activation volume, so as to obtain a plurality of slice groups (S102); quantizing each slice group respectively by using a quantization parameter corresponding to each slice group obtained through a quantization formula (S103). The quantization error can be reduced through the above method.

Abstract: An application of ellagic acid and a metabolic derivative urolithin compound thereof in preparation of an immunomodulatory medicine is provided. Classical animal models of autoimmunity and immunoregulation, such as experimental autoimmune encephalomyelitis, neuromyelitis optica mouse model, ulcerative colitis, and skin transplantation, are used as examples to conduct experiments from various aspects and perspectives, such as neurological function scores, histopathological changes of lesions, inflammatory factor expression, and pro-inflammatory cell numbers.

Abstract: An integrated platform system that employ a series of machine learning techniques and prediction and detection units that can process input data and extract and generate meaningful insights and predictions therefrom. The system integrates together multiple different data storage types and applications that generates data of different types, and an associated processing system for processing the different data types, store the data in a common data model to normalize the data, determine the data lineage of the data, and then process the data using different types of techniques. The data can also be processed by a prediction unit for generating meaningful insights and predictions or by an anomaly detection unit for detecting one or more anomalies in the data.

Abstract: Nitrogen-doped carbon-based catalyst sheets, methods for producing such carbon-based catalyst sheets, and their use as electrocatalysts in oxygen reduction reaction (ORR). A carbon-based catalyst comprising: carbon-based sheets, wherein the carbon-based sheets comprise nitrogen and a transition metal, and wherein the carbon-based sheets further comprise a plurality of micropores, mesopores, macropores, or combinations thereof.

Abstract: Described herein are systems and methods of converting media dimensions. A device may identify a set of frames from a video in a first orientation as belonging to a scene. The device may receive a selected coordinate on a frame of the set of frames for the scene. The device may identify a first region within the frame including a first feature corresponding to the selected coordinate and a second region within the frame including a second feature. The device may generate a first score for the first feature and a second score for the second feature. The first score may be greater than the second score based on the first feature corresponding to the selected coordinate. The device may crop the frame to include the first region and the second region within a predetermined display area comprising a subset of regions of the frame in a second orientation.

Abstract: The present invention discloses a vessel collision avoiding system and method based on Artificial Potential Field algorithm, the method comprises the following steps: (S1) obtaining a vessel information, at least one obstacle information and a target information; (S2) establishing an Artificial Potential Field (APF) by the vessel information, the at least one obstacle information and the target information, wherein the Artificial Potential Field comprises an attractive field of the target and a repulsive field of the obstacle; (S3) combining the attractive field and the repulsive field to obtain a first resultant force; (S4) Adding an external force to the Artificial Potential Field based on the vessel information or the obstacle information; (S5) combining the first resultant force and the external force to obtain a second resultant force; and (S6) the vessel sails in the direction of the second resultant force to avoid the obstacle.

Abstract: Disclosed is a user equipment for satellite communication, comprising one or more processing circuits configured to execute the following operations: evaluating a transmission power requirement for a user equipment to communicate with a satellite; and assisting, via an auxiliary device, the user equipment in executing at least part of the communication with the satellite when the transmission power constraint of the user equipment fails to meet the transmission power requirement, wherein the processing circuits are further configured to acquire, via the satellite, a communication mode to be switched to, and the processing circuits transmit, to the satellite, a notification indicating that a current communication mode needs to be switched, with the notification comprising information indicating the need to switch to a communication mode that meets the transmission power requirement.

Abstract: Described herein are compounds of Formula I, wherein the variables are defined herein, their use as branched-chain alpha keto acid dehydrogenase kinase inhibitors and/or degraders, pharmaceutical compositions containing such compounds and their use to treat, for example, diabetes, kidney disease, NASH and heart failure.

Abstract: A method of dicing a wafer includes positioning the wafer with its top side on a tape material. The wafer includes a plurality of die separated by scribe streets. A first pass being a first infrared (IR) laser beam is directed at the bottom side with a point of entry within the scribe streets. The first IR laser beam is focused with a focus point embedded within a thickness of the wafer, and has parameters selected to form an embedded crack line within the wafer. The embedded crack line does not reach the top side surface. A second pass being a second IR laser beam is directed at the bottom side having parameters selected to form a second crack line that that has a spacing relative to the embedded crack line, and the second IR laser beam causes the embedded crack line to be extended to the top side surface.

Abstract: The present invention provides use of lncRNA XR_595534.2 in the preparation of a medicine for the treatment or prevention of chronic pain. In the present invention, trigeminal neuralgia induced by chronic constriction injury of infraorbital nerve in rats is used as a pain model. A specifically and differentially highly expressed long-chain non-coding RNA gene lncRNA XR_595534.2 is screened in the model. An interfering RNA targeting lncRNA XR_595534.2 is provided for disease treatment. The present invention discovers for the first time that lncRNA XR_595534.2, which is specifically and differentially highly expressed in a pain model, has significantly reduced expression by stereotactic injection of an interfering RNA to relieve the pain behavior, and is useful in the preparation of a medicine for the treatment or prevention of trigeminal neuralgia, neuropathic pain, migraine and cancer pain where lncRNA-XR595534.2 is a target.

Abstract: In an embodiment, an apparatus an apparatus including a memory module is described. The memory module can include a plurality of memory ranks and a register clock driver (RCD) coupled to the plurality of memory ranks. The RCD can include a receiver configured to receive a chip select signal for selecting one or more memory ranks. The RCD can further include a logic circuit coupled to the receiver, and an output driver coupled to the logic circuit. The RCD can further include a loopback circuit configured to sample the chip select signal from one or more of a first sampling point between the receiver and the logic circuit and a second sampling point between the logic circuit and the output driver.

Abstract: Embodiments of the present application provide a method, an apparatus, a computer device for convolution operation and a computer readable storage medium. The method includes: obtaining input data of a network layer in a convolutional neural work; extracting each time a plurality of data points from the input data according to a preset step size; mapping the plurality of data points extracted each time to the same position at different depth levels of three-dimensional data to obtain rearranged data; and performing convolution operation on the rearranged data with a convolution kernel of a preset size to obtain a convolution result. Through the present solution, the operation efficiency of the convolutional neural network can be improved.

Abstract: An electronic equipment, a user equipment, a wireless communication method, and a storage medium, the electronic equipment comprising a processing circuit and being configured to: receive from a user equipment a random access request message that is expected to access a satellite equipment; and in response to the random access request message, send to the user equipment the advance in timing between the user equipment and the satellite equipment to be accessed. By using said electronic equipment, user equipment, wireless communication method, and storage medium, a user equipment in a satellite communication system may more quickly and efficiently acquire control information relating to uplink transmission.

Abstract: Methods and systems are provided for vehicle speed planning based on timing of traffic lights. In an exemplary embodiment, a disclosed system includes one or more sensors of a vehicle; a transceiver; and a processor. The one or more sensors are configured to obtain vehicle sensor data pertaining to operation of the vehicle. The transceiver is configured to obtain traffic light data with respect to a plurality of traffic lights along a path or roadway on which the vehicle is travelling. The processor is coupled to the one or more sensors and to the transceiver, and is configured to at least facilitate: determining a desired control of movement of the vehicle based on the vehicle sensor data, the traffic light data, and one or more optimization criteria pertaining to the vehicle; and taking a vehicle action based on the desired control of movement of the vehicle.

Abstract: Aspects of the disclosed technology provide techniques for determining frictional forces bearing on a downhole drill string. In some implementations, a method of the disclosed technology can include steps for segmenting a plurality of continuous nodes of the drilling string into a first segment and a second segment, computing a first set of values corresponding with one or more nodes in the first segment using a first model, computing a second set of values corresponding with one or more nodes in the second segment using a second model, and determining a torque of the drill string based on the first set of values and the second set of values. In some aspects, the method can further include steps for determining a drag force on the drill string based on the first set of values and the second set of values. Systems and machine-readable media are also provided.

Abstract: A method of removing fixed pattern noise, comprising: S01: performing a single-frame segmented exposure on a pixel array; S02: reading a of the pixel array, comprising: S021: performing a soft reset, so as to set the reset signal of the pixel unit to an intermediate voltage, and reading a differential reset signal; S022: performing a hard reset so as to set the reset signal of the pixel unit to a high voltage; S023: turning on a transmission MOS transistor to enable an exposure signal of to photodiode to transmitted to the floating diffusion area, and reading a differential pixel transmission signal; S03: subtracting the differential reset signal from the differential pixel transmission signal to obtain an exposure signal with fixed pattern noise removed. Another method is removing fixed pattern noise and an image sensor are further provided.

Abstract: The present disclosure provides a display touch device and a control method. The display touch device includes a display panel, a display touch driving circuit and a touch operation processing circuit, wherein the display panel includes a plurality of gate lines; the touch operation processing circuit is configured to provide a first touch enable signal to the display touch driving circuit when it is detected that the display touch device is in a touch-only detection state, to control the display touch driving circuit to perform touch detection. The present disclosure can conveniently perform touch detection when the display touch device is in the touch-only detection state.

Abstract: Described herein are systems and methods of converting media dimensions. A device may identify a set of frames from a video in a first orientation as belonging to a scene. The device may receive a selected coordinate on a frame of the set of frames for the scene. The device may identify a first region within the frame including a first feature corresponding to the selected coordinate and a second region within the frame including a second feature. The device may generate a first score for the first feature and a second score for the second feature. The first score may be greater than the second score based on the first feature corresponding to the selected coordinate. The device may crop the frame to include the first region and the second region within a predetermined display area comprising a subset of regions of the frame in a second orientation.