Abstract: ?-lactamase inhibitors, pharmaceutical compositions including the same, methods of preparing the same, and methods of treating bacterial infections in combination with ?-lactam antibiotics, including infection caused by drug resistant organisms and especially multi-drug resistant organisms. The present invention includes compounds according to formula (I) or pharmaceutically acceptable salts thereof, wherein M and R are as defined herein.

Abstract: A monobactam compound of formula (I), a preparation thereof, and a use thereof as antibiotic agents for the treatment of bacterial infections are provided. In the formula (I), M is hydrogen or a pharmaceutically acceptable salt forming cation, R1 and R2 represent independently of one another hydrogen or methyl, W represents a bond or O, X represents CR4 or N, R4 represents halogen, R3 represents hydrogen, amino, hydroxy, (C1-C6)-alkyl, or a 4-, 5- or 6-membered nitrogen-containing heterocycle.

Abstract: Provided are ?-lactam compounds of formula (I), their preparation and use as antibiotic agents for the treatment of bacterial infections: Wherein X, W, R1, R2 and R3 are defined herein.

Abstract: A multimedia information display method is provided. The method includes: obtaining to-be-displayed multimedia information, where the to-be-displayed multimedia information includes main multimedia information and at least one piece of additional multimedia information having an association relationship; displaying the main multimedia information on a display interface; determining a cover for the at least one piece of additional multimedia information when the main multimedia information is displayed for a preset time period, and displaying the main multimedia information and the cover on the display interface; and switching, in response to a clicking operation on the cover, the main multimedia information displayed on the display interface into the additional multimedia information corresponding to the clicking operation.