Patents by Inventor Yuanyuan GAO

Yuanyuan GAO has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240131086
    Abstract: The present disclosure provides use of Clostridium ghonii combined with a tumor angiogenesis inhibitor in preparing a pharmaceutical product for treating a tumor. The present disclosure further provides a drug for treating a tumor, where the drug includes active ingredients of Clostridium ghonii and a tumor angiogenesis inhibitor.
    Type: Application
    Filed: October 9, 2022
    Publication date: April 25, 2024
    Inventors: Yong Wang, Yuanyuan Liu, Wenhua Zhang, Yanqiu Xing, Shaopeng Wang, Dan Wang, Hong Zhu, Xinglu Xu, Shengbiao Jiang, Xiaonan Li, Jiahui Zheng, Rong Zhang, Dongxia Yang, Yuxia Gao, Shili Shao, Ting Han
  • Publication number: 20240132120
    Abstract: A power decentralized electric locomotive apparatus includes an electric locomotive and a plurality of muck trucks. The electric locomotive and the plurality of muck trucks are connected in sequence, and a mater drive motor is fixedly mounted on the electric locomotive. A slave drive motor is fixedly mounted on at least one of the muck trucks; a torque of the slave drive motor is smaller than a torque of the mater drive motor; and the slave drive motor cooperates with the mater drive motor, to enable the muck truck to travel on rails and reduce drive power and self-weight of the electric locomotive.
    Type: Application
    Filed: November 12, 2021
    Publication date: April 25, 2024
    Applicant: China Railway Engineering Services Co., Ltd.
    Inventors: Yuanshun Zhuang, Yang Deng, Caihong Li, Yuanyuan Mei, Wenju Chen, Longguan Zhang, Kaifu Li, Rui Han, Heng Li, Chuan Li, Jun Zheng, Yang Qian, Tao Du, Xudong Gao, Yuchen Wang, Chuanying Jiang, Jie Li
  • Publication number: 20240115627
    Abstract: The present disclosure relates to use of a Clostridium ghonii spore combined with pembrolizumab in cancer treatment. It is found for the first time that the Clostridium ghonii spore combined with pembrolizumab can significantly improve a curative effect of colon cancer and reduce a dose of the pembrolizumab, and thus is efficient and low-toxic. Oncolysis by Clostridium ghonii can affect immunogenicity of a tumor microenvironment (TME) by various ways, converts an immunosuppressive state of the TME into an immune-activated state, adjusts the immunosuppressive TME, and breaks an immune tolerance. An optimal combination of the Clostridium ghonii spore and the pembrolizumab thoroughly removes about 20% of mouse tumor tissues. A benefit range of patients with tumors treated by a PD-1 antibody is expanded. The combination even has an obvious curative effect on patients failed the treatment by the PD-1 antibody.
    Type: Application
    Filed: October 9, 2022
    Publication date: April 11, 2024
    Inventors: Yong Wang, Hong Zhu, Wenhua Zhang, Yanqiu Xing, Dan Wang, Yuanyuan Liu, Shaopeng Wang, Jiahui Zheng, Rong Zhang, Xiaonan Li, Xinglu Xu, Shengbiao Jiang, Lichao Xing, Yuxia Gao, Shili Shao, Ting Han
  • Publication number: 20240078444
    Abstract: The invention discloses a vehicle fault reasoning method based on a knowledge graph, includes: constructing a knowledge graph of a vehicle fault; obtaining a question statement (QS) from user; performing question classification on the QS by TextCNN to obtain a classification result; marking a training QS by using an NER data marking manner and training an entity extraction model based on a sequence marking result; generating a vehicle fault class by a decision tree model for extracting the QS and searching for an answer in the knowledge graph; and performing question template matching based on the classification result and the answer and substituting the answer into the question template to obtain an answer statement. A question answering system constructed by the method includes word processing, question classification, question template matching, and answer generation, which helps the user judging a fault problem of vehicle, and searching for related knowledge about vehicle fault.
    Type: Application
    Filed: November 15, 2022
    Publication date: March 7, 2024
    Applicant: SHANGHAI UNIVERSITY of ENGINEERING SCIENCE
    Inventors: Zhijun Fang, Yuanyuan Li, Yongbin Gao, Weibing Wan
  • Publication number: 20220218066
    Abstract: The present invention discloses a power-generating insole based on fabric integration, which comprises a power-generating insole body, a detachable outer layer and an electronic module; The power-generating insole comprises a first friction component, a second friction component and a fabric composite component; The first friction component is composed of a first electrode layer and a first polymer material; The first friction component and the fabric composite component are integrally formed; The second friction component is wrapped around the middle part of the fabric composite component, and is integrated with the first friction component and the fabric composite component; The detachable outer layer is wrapped on the surface of the power-generating insole body; The electronic module is connected to the power-generating insole body; The present invention has long service life, good flexibility, plasticity, is washing resistance and stability.
    Type: Application
    Filed: August 31, 2021
    Publication date: July 14, 2022
    Inventors: Chou Har WU, Bingang XU, Meiqi LI, Yuanyuan GAO, Yujue YANG