Patents by Inventor Yuchuan Guo

Yuchuan Guo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Non-anticoagulant heparin derivatives
    Patent number: 5280016
    Abstract: A non-anticoagulant (NAC) form of heparin which shows antiproliferative activity with respect to smooth muscle cells is useful in the prevention of restenosis and other conditions benefited by antiproliferative activity with respect to smooth muscle cells. This NAC form of heparin is prepared by oxidizing heparin/heparan sulfate to a desired level with periodate followed by reduction of the resulting aldehyde groups; all under conditions which prevent depolymerization of the heparin.
    Type: Grant
    Filed: September 3, 1991
    Date of Patent: January 18, 1994
    Assignee: Glycomed Incorporated
    Inventors: H. Edward Conrad, Yuchuan Guo
  • Non-anticoagulant heparin derivatives
    Patent number: 5250519
    Abstract: A non-anticoagulant (NAC) form of heparin which shows antiproliferative activity with respect to smooth muscle cells is useful in the prevention of restenosis and other conditions benefited by antiproliferative activity with respect to smooth muscle cells. This NAC form of heparin is prepared by deacetylating and then oxidizing heparin/heparan sulfate substantially to completion with periodate followed by reduction of the resulting aldehyde groups under conditions which prevent depolymerization of the heparin.
    Type: Grant
    Filed: March 29, 1991
    Date of Patent: October 5, 1993
    Assignee: Glycomed Incorporated
    Inventors: H. Edward Conrad, Yuchuan Guo