Patents by Inventor Yudao Shen

Yudao Shen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SOX11 INHIBITORS FOR TREATING MANTLE CELL LYMPHOMA
    Publication number: 20230242496
    Abstract: Disclosed are compounds that are chemical inhibitors of SOX11. The compounds disclosed are useful in treatment of various cancers.
    Type: Application
    Filed: June 15, 2021
    Publication date: August 3, 2023
    Applicant: Icahn School of Medicine At Mount Sinai
    Inventors: Jian JIN, Marta FILIZOLA, Aneel AGGARWAL, Samir PAREKH, Abhijeet KAPOOR, Shashidhar S. JATIANI, H. Umit KANISKAN, Jianping HU, Yudao SHEN, Fanye MENG, Lihuai QIN, Yulin HAN, Xufen YU, Chengwei ZHANG, Prashasti KUMAR, Rinku JAIN, Clement LEE
  • PROTEIN ARGININE METHYLTRANSFERASE 5 (PRMT5) DEGRADATION / DISRUPTION COMPOUNDS AND METHODS OF USE
    Publication number: 20210261538
    Abstract: Disclosed are protein arginine methyltransferase 5 (PRMT5) degradation/disruption compounds including a PRMT5 ligand, a degradation/disruption tag and a linker, and methods for use of such compounds in the treatment of PRMT5-mediated diseases. The PRMT5 degraders disclosed herein offer a novel mechanism for treating PRMT5-mediated diseases compared to small molecule inhibitors of PRMT5 activity.
    Type: Application
    Filed: February 22, 2019
    Publication date: August 26, 2021
    Inventors: Jian Jin, Jing Liu, Yudao Shen, Ernesto Guccione, Martin Walsh, Almudena Bosch, Megan Schwarz