Patents by Inventor Yuenan Qiu

Yuenan Qiu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for preparing amantadine
    Patent number: 11639328
    Abstract: A method for preparing amantadine includes chlorinating adamantane with chlorine gas in a solvent in the presence of a Lewis acid catalyst to obtain a reaction liquid, and then removing the solvent and residues containing the catalyst in the reaction liquid, to obtain a chlorinated product. The chlorinated product is mixed with urea to a mixture, and the mixture is subjected to an amination reaction, to obtain amantadine. The results of examples show that the purity of the prepared amantadine could reach 99.5% or more.
    Type: Grant
    Filed: May 19, 2020
    Date of Patent: May 2, 2023
    Assignee: Shandong Holly Pharmaceutical Co., Ltd.
    Inventors: Lanhua Li, Yuenan Qiu, Donghong Xu, Zhiyuan Liu, Huaqiang Wu, Zhufeng Zhou, Lihong Chen, Zhen Lin
  • METHOD FOR PREPARING AMANTADINE
    Publication number: 20220251023
    Abstract: A method for preparing amantadine includes chlorinating adamantane with chlorine gas in a solvent in the presence of a Lewis acid catalyst to obtain a reaction liquid, and then removing the solvent and residues containing the catalyst in the reaction liquid, to obtain a chlorinated product. The chlorinated product is mixed with urea to a mixture, and the mixture is subjected to an amination reaction, to obtain amantadine. The results of examples show that the purity of the prepared amantadine could reach 99.5% or more.
    Type: Application
    Filed: May 19, 2020
    Publication date: August 11, 2022
    Inventors: Lanhua Li, Yuenan Qiu, Donghong Xu, Zhiyuan Liu, Huaqiang Wu, Zhufeng Zhou, Lihong Chen, Zhen Lin