Abstract: The disclosure relates to an automatic measuring system and a method thereof for drilling fluid parameters measurement. The system includes i. mud container, configured for test drilling fluid preparation and samples collection; ii. heat jacket, configured to keep the drilling fluid in the tank warm iii. heat exchanger, configured to simulate the practical conditions; iv. plunger pump, configured to pump the test drilling fluid to the flowing test device; v. flow test device, configured to simulate the flowing states of drilling fluid in the borehole annulus and drilling string, and also measure the pressure and flow rate of drilling fluid vi. control module, configured to obtain rheological parameters and the best rheological mode of the drilling fluid in the borehole annulus and drilling string based on the pressure and flow rate.

Abstract: An amino acid sequence that can destroy cells, a nucleotide sequence encoding and expressing the corresponding amino acid sequence, and the related uses of the amino acid sequence and the nucleotide sequence are provided. The amino acid sequence has the amino acid sequence shown in SEQ ID NO: 1 and/or SEQ ID NO: 29.

Abstract: The invention relates to an automatic measuring system and a use method thereof for drilling fluid parameters measurement under high temperature and high-pressure conditions. The system is composed of six parts: i. mud container, used both for test drilling fluid preparation and the tested samples collection; ii. heat jacket, which is arranged on the outer surface of the fluid tank and used to keep the drilling fluid in the tank warm by heating; iii. heat exchanger, receive the test drilling fluid from the tank and heat it to simulate the practical conditions; iv. plunger pump, which is used to pump the test drilling fluid to the flowing test device; v. moveable test device, used to simulate the flowing states of drilling fluid in the borehole annulus and drilling string, and also measure the pressure and flow rate of drilling fluid in the inlet and outlet of the test device; vi.

Abstract: The invention provides a mud circulation system for reducing swab pressure while tripping out, including drilling tool components, a normal drilling circulation channel and a tripping circulation channel, the drilling tool components include a drill string, a drill bit, and a top drive, the normal drilling circulation channel includes a first rotary valve, a solid phase control device, a mud tank, a mud pump, and a forth rotary valve connected in sequence, the tripping circulation channel includes a second rotary valve, a tripping mud pump, a tripping mud tank and a third rotary valve connected in sequence; the mud circulation system for reducing the swab pressure is operated to: shut down the mud pump, close the first rotary valve, and open the second rotary valve and the third rotary valve before tripping out; determine the pumping flow rate according to relevant parameters.

Abstract: The invention provides a mud circulation system for reducing swab pressure while tripping out, including drilling tool components, a normal drilling circulation channel and a tripping circulation channel, the drilling tool components include a drill string, a drill bit, and a top drive, the normal drilling circulation channel includes a first rotary valve, a solid phase control device, a mud tank, a mud pump, and a forth rotary valve connected in sequence, the tripping circulation channel includes a second rotary valve, a tripping mud pump, a tripping mud tank and a third rotary valve connected in sequence; the method to operate the mud circulation system for reducing the swab pressure is as follows: shutting down the mud pump, closing the first rotary valve, and opening the second rotary valve and the third rotary valve before tripping out; determining the pumping flow rate according to relevant parameters.