Patents by Inventor Yuguang Du

Yuguang Du has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11970576
    Abstract: There is provided a ?-peptido sugar-copolymer having the structure of formula (I) as defined herein, or a stereoisomer, a tautomer, an N-oxide, a hydrate, a solvate, or a salt thereof, or a mixture of the same. There is provided a process to make the ?-peptido sugar-copolymer as defined herein. There are further provided medical applications of the ?-peptido sugar-copolymer as defined herein. In a preferred embodiment, a block-like copolymer poly(amido-D-glucose)-block-poly-?-(L)-homolysine (PDGu-b-PBLK) synthesized via anionic ring-opening polymerization (ROP) demonstrates an antimicrobial efficacy, an enhanced selectivity towards different bacteria, biocompatibility vs. mammalian cells and spontaneous assembly.
    Type: Grant
    Filed: January 12, 2018
    Date of Patent: April 30, 2024
    Assignee: NANYANG TECHNOLOGICAL UNIVERSITY
    Inventors: Bee Eng Mary Chan, Yu Du, Rubi Zamudio Vazquez, Kaixi Zhang, Zhangyong Si, Yuguang Mu, Hongwei Duan
  • Publication number: 20230212210
    Abstract: The present application belongs to the field of life health, and discloses a sugar chain and a composition thereof, and use in the prevention and/or treatment of coronavirus infection. The sugar chain contains any one or more of Neu5Ac?2-N1Gal building blocks, and/or any one or more of xFuc-N1Gal-N1(xFuc-N1)GlcNAc building blocks, at the non-reducing end, where, x=0 or 1, and N1=1, 2, 3, 4 or 6. A glycosidic bond formed between Neu5Ac and Gal is an ?2 glycosidic bond. In the xFuc-N1Gal-N1(xFuc-N1)GlcNAc building blocks, a glycosidic bond formed between any two adjacent monosaccharides is an ?1 or ?1 glycosidic bond. The specific building block contained at the non-reducing end of the sugar chain blocks the binding of the virus to the host, thereby blocking virus invasion and infection of the respiratory tract/lung, and achieving the specific prevention and treatment.
    Type: Application
    Filed: July 26, 2021
    Publication date: July 6, 2023
    Applicant: Institute of Process Engineering, Chinese Academy of Sciences
    Inventors: Yuguang DU, Jianjun LI, Yueqiang XU, Zhuo WANG, Dongdong LIU, Yalu YAN, Qi WANG, Xin YOU, Xiaohui DU
  • Patent number: 11319519
    Abstract: The microfluidic chip can comprise at least one multichamber flow assembly that can comprise a plurality of microchannels. The plurality of microchannels can comprise a first microchannel that includes: a first inlet; a first outlet; and a first chamber fluidly connected to the first inlet and the first outlet. The plurality of microchannels can comprise a second microchannel that includes: a second inlet; a second outlet; and a second chamber fluidly connected to the second inlet and the second outlet. The multichamber flow assembly can comprise a porous biocompatible membrane oriented along a longitudinal interface between the first microchannel and the second microchannel, wherein the porous biocompatible membrane is permeable for movement of biomolecules from the first chamber to the second chamber through the porous biocompatible membrane.
    Type: Grant
    Filed: December 12, 2019
    Date of Patent: May 3, 2022
    Assignees: MACAU GLCAO Biotechnology Research Center Limited, Calroy Health Sciences, LLC
    Inventors: Yong Luo, Jinhua Wei, Zhou Wang, Ming Sun, Chen Chen, Yuguang Du
  • Publication number: 20200199510
    Abstract: The microfluidic chip can comprise at least one multichamber flow assembly that can comprise a plurality of microchannels. The plurality of microchannels can comprise a first microchannel that includes: a first inlet; a first outlet; and a first chamber fluidly connected to the first inlet and the first outlet. The plurality of microchannels can comprise a second microchannel that includes: a second inlet; a second outlet; and a second chamber fluidly connected to the second inlet and the second outlet. The multichamber flow assembly can comprise a porous biocompatible membrane oriented along a longitudinal interface between the first microchannel and the second microchannel, wherein the porous biocompatible membrane is permeable for movement of biomolecules from the first chamber to the second chamber through the porous biocompatible membrane.
    Type: Application
    Filed: December 12, 2019
    Publication date: June 25, 2020
    Inventors: Yong Luo, Jinhua Wei, Zhou Wang, Ming Sun, Chen Chen, Yuguang Du
  • Publication number: 20180245169
    Abstract: The present invention belongs to the field of microbial detection, and in particular, relates to nucleic acid sequences for typing detection of cutaneous human papillomaviruses (HPVs) and use thereof. The 30 primer pairs are useful in the preparation of a diagnostic product, for example, a kit, for rapidly detecting the types of cutaneous HPVs. By using the nucleotide sequences, the types of cutaneous HPVs can be rapidly and accurately detected, thereby meeting the requirement for typing detection of cutaneous HPVs in clinic.
    Type: Application
    Filed: February 15, 2018
    Publication date: August 30, 2018
    Inventors: Xinghua Gao, Yuguang Du, Ge Ge, Rui Mao, Ruiqun Qi, Ming Sun, Hong-Duo Chen
  • Patent number: 9700068
    Abstract: A formulation of complex carbohydrates for fodder, fodder comprising the same, and application, the fodder comprising of the following ingredients: corn, bean pulp, whey powder, fish meal, soymilk, wheat middling, piglet premix, glucose and a formulation of complex carbohydrates, and the formulation of complex carbohydrates consisting of flucose, galactose, N-acetylgalactosamine, glucosamine, acetylglucosamine, glucuronic acid, mannose, sialic acid and xylose.
    Type: Grant
    Filed: November 19, 2013
    Date of Patent: July 11, 2017
    Assignee: INSTITUTE OF PROCESS ENGINEERING, CHINESE ACADEMY OF SCIENCES
    Inventors: Yuguang Du, Qingsong Xu, Bo Shi, Qishun Liu, Gong Cheng
  • Publication number: 20160295885
    Abstract: A formulation of complex carbohydrates for fodder, fodder comprising the same, and application, the fodder comprising of the following ingredients: corn, bean pulp, whey powder, fish meal, soymilk, wheat middling, piglet premix, glucose and a formulation of complex carbohydrates, and the formulation of complex carbohydrates consisting of flucose, galactose, N-acetylgalactosamine, glucosamine, acetylglucosamine, glucuronic acid, mannose, sialic acid and xylose.
    Type: Application
    Filed: November 19, 2013
    Publication date: October 13, 2016
    Inventors: Yuguang DU, Qingsong XU, Bo SHI, Qishun LIU, Gong CHENG
  • Patent number: 9327271
    Abstract: The present invention relates to catalysts and methods for efficient conversion of carbohydrates into 5-hydroxymethylfurfural (HMF), which shows good activity and high selectivity for HMF preparation from saccharides. The catalyst is stable in aqueous system which makes it as an ideal catalyst for HMF production. High HMF yield was obtained even in mild condition. The catalysts of the invention are advantageous in that they are environment-friendly, easy separation and recovery, can be re-used in subsequent reactions, do not corrode reaction reactors. These features make the catalyst as a suitable catalyst for HMF preparation and have strong industrial application significance.
    Type: Grant
    Filed: June 18, 2014
    Date of Patent: May 3, 2016
    Assignee: DALIAN INSTITUTE OF CHEMICAL PHYSICS, CHINESE ACADEMY OF SCIENCES
    Inventors: Qishun Liu, Heng Yin, Yuguang Du, Fengli Yang, Wenxia Wang
  • Publication number: 20140302982
    Abstract: The present invention relates to catalysts and methods for efficient conversion of carbohydrates into 5-hydroxymethylfurfural (HMF), which shows good activity and high selectivity for HMF preparation from saccharides. The catalyst is stable in aqueous system which makes it as an ideal catalyst for HMF production. High HMF yield was obtained even in mild condition. The catalysts of the invention are advantageous in that they are environment-friendly, easy separation and recovery, can be re-used in subsequent reactions, do not corrode reaction reactors. These features make the catalyst as a suitable catalyst for HMF preparation and have strong industrial application significance.
    Type: Application
    Filed: June 18, 2014
    Publication date: October 9, 2014
    Inventors: Qishun LIU, Heng YIN, Yuguang DU, Fengli YANG, Wenxia WANG
  • Patent number: 8785668
    Abstract: The present invention relates to a method for efficient conversion of carbohydrates into 5-hydroxymethylfurfural (HMF) in the presence of tantalum-containing solid acid, which shows good activity and high selectivity for HMF preparation from saccharides. The catalyst is stable in aqueous system which makes it as an ideal catalyst for HMF production. High HMF yield was obtained even in mild condition. The catalysts of the invention are advantageous in that they are environment-friendly, easy separation and recovery, can be re-used in subsequent reactions, do not corrode reaction reactors. These features make the catalyst as an ideal catalyst for HMF preparation and have strong industrial application significance.
    Type: Grant
    Filed: November 30, 2010
    Date of Patent: July 22, 2014
    Assignee: Dalian Institute of Chemical Physics, Chinese Academy of Sciences
    Inventors: Yuguang Du, Qishun Liu, Fengli Yang, Xuefang Bai, Jingmei Zhao
  • Publication number: 20130281719
    Abstract: The present invention relates to a method for efficient conversion of carbohydrates into 5-hydroxymethylfurfural (HMF) in the presence of tantalum-containing solid acid, which shows good activity and high selectivity for HMF preparation from saccharides. The catalyst is stable in aqueous system which makes it as an ideal catalyst for HMF production. High HMF yield was obtained even in mild condition. The catalysts of the invention are advantageous in that they are environment-friendly, easy separation and recovery, can be re-used in subsequent reactions, do not corrode reaction reactors. These features make the catalyst as an ideal catalyst for HMF preparation and have strong industrial application significance.
    Type: Application
    Filed: November 30, 2010
    Publication date: October 24, 2013
    Applicant: Dalian Institute of Chemical Physics, Chinese Academy of Sciences
    Inventors: Yuguang Du, Qishun Liu, Fengli Yang, Xuefang Bai, Jingmei Zhao