Patents by Inventor Yuh-Ling Chen

Yuh-Ling Chen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for treating periodontal diseases
    Patent number: 11214840
    Abstract: Provided herein are aptamers that bind specifically to the surface proteins of periodontal pathogens. Also provided herein are methods for detecting and treating periodontal disease in a subject. The method comprises detecting bacteria associated with periodontal disease by use of the present aptamers to analyze a sample taken from a gum pocket of a tooth of the subject; and treating the periodontal disease of the subject by administering to the gum pocket of the tooth a bactericide or an anti-microbial phototherapy to eradicate the bacteria associated with periodontal disease.
    Type: Grant
    Filed: October 7, 2019
    Date of Patent: January 4, 2022
    Assignee: NATIONAL CHENG KUNG UNIVERSITY
    Inventors: Ping-Ching Wu, Dar-Bin Shieh, Fong-Yu Cheng, Yuh-Ling Chen
  • METHODS FOR TREATING PERIODONTAL DISEASES
    Publication number: 20200172961
    Abstract: Provided herein are aptamers that bind specifically to the surface proteins of periodontal pathogens. Also provided herein are methods for detecting and treating periodontal disease in a subject. The method comprises detecting bacteria associated with periodontal disease by use of the present aptamers to analyze a sample taken from a gum pocket of a tooth of the subject; and treating the periodontal disease of the subject by administering to the gum pocket of the tooth a bactericide or an anti-microbial phototherapy to eradicate the bacteria associated with periodontal disease.
    Type: Application
    Filed: October 7, 2019
    Publication date: June 4, 2020
    Applicant: NATIONAL CHENG KUNG UNIVERSITY
    Inventors: Ping-Ching WU, Dar-Bin SHIEH, Fong-Yu CHENG, Yuh-Ling CHEN
  • Aptamers of surface proteins of periodontal pathogens and uses thereof
    Patent number: 10487331
    Abstract: Disclosed herein are aptamers that bind specifically to the surface proteins of periodontal pathogens. Disclosed also herein are kits and methods for detecting bacteria associated with periodontal disease by using the present aptamers to analyze a sample taken from the oral cavity of a patient.
    Type: Grant
    Filed: November 30, 2018
    Date of Patent: November 26, 2019
    Assignee: NATIONAL CHENG KUNG UNIVERSITY
    Inventors: Ping-Ching Wu, Dar-Bin Shieh, Fong-Yu Cheng, Yuh-Ling Chen
  • MICROFLUIDIC CHIP DEVICE FOR SELECTING A CELL APTAMER AND METHOD THEREOF
    Publication number: 20130164755
    Abstract: The present invention provides a microfluidic chip device for selecting a cell aptamer. The microfluidic chip device comprising a plurality of storage reservoirs; a fluid control unit; a reaction tank; and a PCR reaction tank, wherein each storage reservoir interconnects with the fluid control unit, and via a corresponding pumping/mixing element, the sample and the reagent are mixed and then transported into each storage reservoir. The present invention further provides a method for selecting a cell aptamer.
    Type: Application
    Filed: May 2, 2012
    Publication date: June 27, 2013
    Applicant: NATIONAL TSING HUA UNIVERSITY
    Inventors: CHEN-HSUN WENG, GWO-BIN LEE, YUH-LING CHEN, SHU-CHU SHIESH
  • Composition for treating cancer and use thereof
    Patent number: 8450283
    Abstract: The present invention provides a cyclic peptide containing RRXR motif. The present invention also provides a composition comprising the said cyclic peptide and a pharmaceutical acceptable carrier. The present invention further provides a method for treating cancer.
    Type: Grant
    Filed: September 10, 2009
    Date of Patent: May 28, 2013
    Assignee: National Taiwan University
    Inventors: Pan-Chyr Yang, Tse-Ming Hong, Yuh-Ling Chen, Ang Yuan, Yi-Ying Wu
  • COMPOSITION FOR TREATING CANCER AND USE THEREOF
    Publication number: 20100022447
    Abstract: The present invention provides a cyclic peptide containing RRXR motif. The present invention also provides a composition comprising the said cyclic peptide and a pharmaceutical acceptable carrier. The present invention further provides a method for treating cancer.
    Type: Application
    Filed: September 10, 2009
    Publication date: January 28, 2010
    Applicant: NATIONAL TAIWAN UNIVERSITY
    Inventors: PAN-CHYR YANG, TSE-MING HONG, YUH-LING CHEN, ANG YUAN, YI-YING WU
  • Composition for treating cancer and use thereof
    Patent number: 7601693
    Abstract: The present invention provides a cyclic peptide containing RRXR motif. The present invention also provides a composition comprising the said cyclic peptide and a pharmaceutical acceptable carrier. The present invention further provides a method for treating cancer.
    Type: Grant
    Filed: February 5, 2008
    Date of Patent: October 13, 2009
    Assignee: National Taiwan University
    Inventors: Pan-Chyr Yang, Tse-Ming Hong, Yuh-Ling Chen, Ang Yuan, Yi-Ying Wu
  • COMPOSITION FOR TREATING CANCER AND USE THEREOF
    Publication number: 20090197798
    Abstract: The present invention provides a cyclic peptide containing RRXR motif. The present invention also provides a composition comprising the said cyclic peptide and a pharmaceutical acceptable carrier. The present invention further provides a method for treating cancer.
    Type: Application
    Filed: February 5, 2008
    Publication date: August 6, 2009
    Applicant: NATIONAL TAIWAN UNIVERSITY
    Inventors: PAN-CHYR YANG, TSE-MING HONG, YUH-LING CHEN, ANG YUAN, YI-YING WU