Patents by Inventor Yuichiro Ota

Yuichiro Ota has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11740254
    Abstract: The object of the invention is to provide an automatic analysis apparatus capable of setting a dispensing mechanism for measuring dispensing accuracy and a dispensing volume, and capable of performing dispensing accuracy measurement without absorbance measurement. Regarding a dispensing accuracy, a dispensing mechanism to be measured is designated. Parameters including a dispensing volume and the like are input. A dispensing operation of the input dispensing volume is automatically performed for each designated dispensing mechanism. A reaction vessel contains, for example, a reagent of the input dispensing volume which has been dispensed by the designated dispensing mechanism. By measuring a weight of the reagent in the reaction vessel, or the like, it is possible to measure the dispensing accuracy of the designated dispensing mechanism.
    Type: Grant
    Filed: November 29, 2018
    Date of Patent: August 29, 2023
    Assignees: Hitachi High-Tech Corporation, Roche Diagnostics Operations, Inc.
    Inventors: Yuichiro Ota, Takaaki Hagiwara, Yoshihiro Yamashita, Koshin Hamasaki, Michaela Windfuhr, Heike Guggemos, Johannes Stoeckel, Guenter Ziegler, Michael Kuehnl
  • Publication number: 20230010798
    Abstract: The invention has an object to provide an automatic analyzer and a control program that can shorten total analysis time. The automatic analyzer comprises: a sample rack that houses a sample; a sample dispensing mechanism that aspirates the sample from the sample rack and dispenses the sample into a reaction container; a plurality of detection units that detect a reaction liquid in the reaction container; and a control unit that controls the sample dispensing mechanism and the detection units. The control unit checks the measurement item specified for the sample and checks one of the detection units that is specified by the measurement item. When measurements specifying the same detection unit among the detection units are specified consecutively, the order of dispensing by the sample dispensing mechanism is changed so that measurements specifying different detection units are made consecutively.
    Type: Application
    Filed: October 27, 2020
    Publication date: January 12, 2023
    Inventors: Yuichiro OTA, Kenta IMAI, Shunsuke SASAKI, Hidekazu TEZUKA, Hiroya UMEKI
  • Publication number: 20220221477
    Abstract: Proposed is a technique for facilitating work of cause investigation of a defect by an operator. The present disclosure proposes an automatic analyzer including: a reagent dispensing unit configured to aspirate a reagent from a reagent vessel that contains the reagent, and discharge the reagent into a reaction vessel that contains a reaction liquid containing a sample; a storage unit configured to store a type of the sample and concentration-related information determined for each type of the sample and related to a concentration of a component to be measured contained in the sample; a detection unit configured to detect a measurement concentration that is the concentration of the component to be measured contained in the reaction liquid; and a determination unit configured to determine whether an abnormality occurs in the reagent vessel based on the concentration-related information and the measurement concentration.
    Type: Application
    Filed: March 3, 2020
    Publication date: July 14, 2022
    Inventors: Hirobumi SHIOHATA, Yuichiro OTA, Takaaki HAGIWARA
  • Patent number: 10711294
    Abstract: The substrate 100 for use in the analysis of a nucleic acid according to the present invention has multiple analysis areas 12 which are partitioned on a substrate 10, and enables the measurement of the analysis areas 12 while interchanging the analysis areas 12 in turn, said substrate 100 being characterized in that each of the analysis areas 12 consists of an adsorption part 13 onto which a DNA fragment or a carrier having the DNA fragment carried thereon can be adsorbed and a non-adsorption part 14 which is a part outside of the adsorption part 13, and the non-adsorption part 14 has, formed on at least a part thereof, a marker part 15 that has a specified shape and helps to identify the positions of the analysis areas 12.
    Type: Grant
    Filed: December 26, 2014
    Date of Patent: July 14, 2020
    Assignee: HITACHI HIGH-TECH CORPORATION
    Inventors: Yuichiro Ota, Tomohiro Shoji, Toru Yokoyama, Masatoshi Narahara
  • Publication number: 20200209273
    Abstract: The object of the invention is to provide an automatic analysis apparatus capable of setting a dispensing mechanism for measuring dispensing accuracy and a dispensing volume, and capable of performing dispensing accuracy measurement without absorbance measurement. Regarding a dispensing accuracy, a dispensing mechanism to be measured is designated. Parameters including a dispensing volume and the like are input. A dispensing operation of the input dispensing volume is automatically performed for each designated dispensing mechanism. A reaction vessel contains, for example, a reagent of the input dispensing volume which has been dispensed by the designated dispensing mechanism. By measuring a weight of the reagent in the reaction vessel, or the like, it is possible to measure the dispensing accuracy of the designated dispensing mechanism.
    Type: Application
    Filed: November 29, 2018
    Publication date: July 2, 2020
    Inventors: Yuichiro OTA, Takaaki HAGIWARA, Yoshihiro YAMASHITA, Koshin HAMASAKI, Michaela WINDFUHR, Heike GUGGEMOS, Johannes STOECKEL, Guenter ZIEGLER, Michael KUEHNL
  • Patent number: 10451553
    Abstract: During analysis of samples of unknown concentration, situations frequently occur in which the dynamic range is insufficient, necessitating reanalysis. Accordingly, a fluorescence spectrometer which splits a single object image into multiple images having different fluorescent intensity by means of image splitting elements, and simultaneously detects the plurality of images obtained thereby in different regions within the same detection plane, is proposed.
    Type: Grant
    Filed: March 18, 2015
    Date of Patent: October 22, 2019
    Assignee: Hitachi High-Technologies Corporation
    Inventors: Motohiro Yamazaki, Yuichiro Ota, Satoshi Takahashi, Yoshitaka Kodama
  • Publication number: 20170362634
    Abstract: The substrate 100 for use in the analysis of a nucleic acid according to the present invention has multiple analysis areas 12 which are partitioned on a substrate 10, and enables the measurement of the analysis areas 12 while interchanging the analysis areas 12 in turn, said substrate 100 being characterized in that each of the analysis areas 12 consists of an adsorption part 13 onto which a DNA fragment or a carrier having the DNA fragment carried thereon can be adsorbed and a non-adsorption part 14 which is a part outside of the adsorption part 13, and the non-adsorption part 14 has, formed on at least a part thereof, a marker part 15 that has a specified shape and helps to identify the positions of the analysis areas 12.
    Type: Application
    Filed: December 26, 2014
    Publication date: December 21, 2017
    Inventors: Yuichiro OTA, Tomohiro SHOJI, Toru YOKOYAMA, Masatoshi NARAHARA
  • Publication number: 20170115223
    Abstract: During analysis of samples of unknown concentration, situations frequently occur in which the dynamic range is insufficient, necessitating reanalysis. Accordingly, a fluorescence spectrometer which splits a single object image into multiple images having different fluorescent intensity by means of image splitting elements, and simultaneously detects the plurality of images obtained thereby in different regions within the same detection plane, is proposed.
    Type: Application
    Filed: March 18, 2015
    Publication date: April 27, 2017
    Inventors: Motohiro YAMAZAKI, Yuichiro OTA, Satoshi TAKAHASHI, Yoshitaka KODAMA
  • Publication number: 20150176070
    Abstract: In a biomaterial analysis, erroneous detection of a particle emitting fluorescence is prevented, and highly sensitive and highly accurate optical detection in biomaterial analysis is performed. A flow cell (104) for biomaterial analysis includes: a light-transmissive upper substrate (310); an antireflective lower substrate (313); and an inner layer section interposed between the upper substrate (310) and the lower substrate (313) and including a flow path (311) in which a particle (312) configured to emit fluorescence is provided. A biomaterial analysis device includes: a flow cell (104) for biomaterial analysis as described above; and an irradiation unit configured to irradiate excitation light; and an optical detection unit (106) configured to detect fluorescence emitted by the particle (312).
    Type: Application
    Filed: July 11, 2013
    Publication date: June 25, 2015
    Inventors: Yuichiro Ota, Tomohiro Shoji, Michiru Fujioka, Takanobu Haga
  • Patent number: 8906671
    Abstract: A chilled reagent container comprises a reagent vessel containing part for containing therein a plurality of reagent vessels, a container lid including a container lid hole through which the reagent vessels contained by the reagent vessel containing part are accessible, and a cooling block for cooling the reagent vessels contained by the reagent vessel containing part, wherein the container lid slides to be changeable between an opened situation wherein the reagent is accessible from an outside and a closed situation wherein the reagent is prevented from being accessed from the outside, wherein the chilled reagent container further comprises a reagent container packing including another hole through which the reagent vessels are accessible and arranged between the container lid and the reagent vessel containing part to be pressed against the container lid.
    Type: Grant
    Filed: June 25, 2012
    Date of Patent: December 9, 2014
    Assignee: Hitachi High-Technologies Corporation
    Inventors: Motohiro Yamazaki, Ryoji Inaba, Shuhei Yamamoto, Takuya Matsui, Kohshi Maeda, Yuichiro Ota, Hiroyuki Higashino
  • Publication number: 20120329143
    Abstract: A chilled reagent container comprises a reagent vessel containing part for containing therein a plurality of reagent vessels, a container lid including a container lid hole through which the reagent vessels contained by the reagent vessel containing part are accessible, and a cooling block for cooling the reagent vessels contained by the reagent vessel containing part, wherein the container lid slides to be changeable between an opened situation wherein the reagent is accessible from an outside and a closed situation wherein the reagent is prevented from being accessed from the outside, wherein the chilled reagent container further comprises a reagent container packing including another hole through which the reagent vessels are accessible and arranged between the container lid and the reagent vessel containing part to be pressed against the container lid.
    Type: Application
    Filed: June 25, 2012
    Publication date: December 27, 2012
    Applicant: Hitachi High-Technologies Corporation
    Inventors: Motohiro Yamazaki, Ryoji Inaba, Shuhei Yamamoto, Takuya Matsui, Kohshi Maeda, Yuichiro Ota, Hiroyuki Higashino