Abstract: As an antitumor drug which is excellent in terms of antitumor effect and safety, there is provided an antibody-drug conjugate in which an antitumor compound represented by the following formula is conjugated to an antibody via a linker having a structure represented by the following formula: -L1-L2-LP-NH—(CH2)n1-La-Lb-Lc- wherein the antibody is connected to the terminal of L1, and the antitumor compound is connected to the terminal of Lc with the nitrogen atom of the amino group at position 1 as a connecting position.

Abstract: A particle separation device comprises, inside a plate-like base body, a straight main flow path including a flow inlet and a plurality of branch flow paths. The flow inlet includes a sample flow inlet and a pressing flow inlet. The sample flow inlet is connected to the main flow path via a first bending part, a first straight part, a second bending part, and a second straight part. Widths in the first bending part and the first straight part are larger than widths in the second bending part and the second straight part. The widths in the second bending part and the second straight part are larger than a width in the main flow path. The pressing flow inlet is connected to the side surface of the main flow path via a third straight part, a third bending part, a fourth straight part, and a fifth straight part.

Abstract: An image analysis device according to the present invention includes: an image capturing unit that captures a subject; a light emitting unit that emits light to the subject; a sensor unit that senses an inclination of the image capturing unit relative to the subject; a control unit that causes the image capturing unit to capture an image of the subject while controlling light emission of the light emitting unit; and a determination unit that, based on a positional relationship of the image capturing unit and the light emitting unit and the inclination, determines a measurement region spaced apart by a predetermined distance from a reflection region corresponding to a position in the image where a light from the light emitting unit regularly reflects at the subject.

Abstract: A measurement apparatus includes: a flow path device including a first flow path in which first liquid including particles to be measured is flowed, and which includes a measurement region measured with an optical sensor, a second flow path in which second liquid for comparison is flowed, and which includes a comparison region measured with the optical sensor, and a calibration region for calibrating the optical sensor; an arm-like member in which the optical sensor is disposed in a first end, and in which a drive shaft is disposed in a second end; and a rotary drive actuator configured to rotationally drive the arm-like member in a predetermined range, wherein each of the measurement region, the comparison region, and the calibration region is disposed as a region including a position on a circumference along which the optical sensor moves in accordance with a rotary drive of the arm-like member.

Abstract: The silicon carbide powder is a powder of silicon carbide having an ?-type crystal system, where the number of small corner portions among corner portions on a surface of a primary particle of silicon carbide constituting the powder of silicon carbide is 2.5 or less per one primary particle. The small corner portion is a corner portion, among corner portions present in a contour of the primary particle in a projection image of the primary particle, where twice a curvature radius of the corner portion is 1/5 or less of a Heywood diameter of the projection image of the primary particle.

Abstract: A band saw blade includes a body part made into a loop in an endless form at a joint part formed by welding, a blade part formed on one edge side of the body part, a first shot blasted part formed on at least one side plane of the body part, a second shot blasted part formed in a part of the first shot blasted par and visually recognized as a range having a surface state different from a surface state of the first shot blasted part, and an information part that is provided to the second shot blasted part and from which information can be acquired.

Abstract: There is provided a silicon carbide powder having a small mean particle diameter and a narrow particle diameter distribution width. A silicon carbide powder is a powder of silicon carbide (SiC) having an ?-type crystal form and has a mean particle diameter of 300 nm or less. In the silicon carbide powder, a ratio D90/D10 between a particle diameter D10 and a particle diameter D90 is 4 or less, the particle diameter D10 being a particle diameter at which the cumulative particle volume from the small particle diameter side in a volume-based cumulative particle diameter distribution reaches 10% of the total particle volume and the particle diameter D90 being a particle diameter at which the cumulative particle volume from the small particle diameter side in the volume-based cumulative particle diameter distribution reaches 90% of the total particle volume.

Abstract: A blood analyzer according to one or more embodiments may include: a specimen preparation part that prepares a measurement specimen by mixing a reagent into a blood preparation; a measurement part that measures the measurement specimen; a measurement mode selection unit that receives an input of a type of blood preparation as a measurement target selected from a plurality of types of blood preparations; and a controller. The controller may cause the specimen preparation part to prepare the measurement specimen depending on the selected type of blood preparation.

Abstract: A blood analyzer according to one or more embodiments may include: a specimen preparation part that prepares a measurement specimen by mixing a reagent into a blood preparation; a measurement part that measures the measurement specimen; a measurement mode selection unit that receives an input of a type of blood preparation as a measurement target selected from a plurality of types of blood preparations; and a controller. The controller may cause the specimen preparation part to prepare the measurement specimen depending on the selected type of blood preparation.

Abstract: A measuring apparatus includes a flow cell through which a sample containing particles flows, a light source for irradiating light on the sample flowing through the flow cell, a fluorescence detector for detecting the fluorescence generated from the sample irradiated with light from the light source, and a control unit for flowing a positive control sample containing a fluorescent dye through the flow cell, measuring the fluorescence generated from the positive control sample irradiated by the light from the light source via the fluorescence detector, comparing the obtained measurement value and a reference value, and adjusting the detection sensitivity of the fluorescence detector according to the comparison result.

Abstract: A flow path device comprises a plate-like measurement flow path device and a plate-like separation flow path device. The measurement flow path device includes a first flow path for measuring specific particles on a first fluid and connected to a third flow path and a second flow path for correction and passing a second fluid, not including the specific particles. The separation flow path device includes a fourth flow path for separating and selecting the specific particles from a sample and collecting a fluid. The separation flow path device is on the measurement flow path device's upper surface. The sample passes through a fifth flow path, the upper surface's opening, and flows into the fourth flow path from an opening in the separation flow path device's lower surface. The first fluid passes through the lower surface's opening, and flows into the first flow path from the upper surface's opening.

Abstract: A stage for heating and cooling an object installed in a chamber 1 includes : a stage body 5, 6 that has a mounting surface on which an object is mounted; a heating unit 7 for heating the mounting surface; and a cooling unit 8 for cooling the mounting surface. The stage body 5, 6 also has a first groove 10 into which the heating unit is inserted and a second groove 10 into which the cooling unit is inserted. The gap between the first groove and the heating unit and the gap between the second groove and the cooling unit have a heat-conductive medium.

Abstract: A flow path device includes a first portion, and a second portion. The first portion includes a resin first body and a first reinforcement. In the first body, a first connector connects a first outer portion and a first joint having a groove pattern defining a first flow path. The first reinforcement is between and bonded to the first outer portion and the first joint, and includes first protrusions protruding from the first body and including two specific-shaped portions. The second portion includes a resin second body and a second reinforcement. In the second body, a second connector connects a second outer portion and a second joint, and through-holes connect to the first flow path. The second reinforcement is between and bonded to the second outer portion and the second joint, and includes second protrusions protruding from the second body and including two specific-shaped portions.

Abstract: The present disclosure provides a ceramic powder having low bulkiness and good dispersibility. In the ceramic powder, the volume ratio of aggregated particles having a particle diameter larger than a reference particle diameter is 35 vol. % or more and the volume ratio when ultrasonic dispersion treatment for 10 minutes at an oscillation frequency of 19.5 kHz and an output power of 10 W is applied is 4 vol. % or less. The reference particle diameter is a particle diameter equivalent to a cumulative 0.1 vol. % diameter from the large diameter side when the ceramic powder is subjected to ultrasonic dispersion treatment for 3 minutes at an oscillation frequency of 19.5 kHz and an output power of 150 W.

Abstract: An image analysis device according to the present invention includes: an image capturing unit that captures a subject; a light emitting unit that emits light to the subject; a control unit that causes the image capturing unit to capture a first image of the subject while causing the light emitting unit to emit light and causes the image capturing unit to capture a second image of the subject while not causing the light emitting unit to emit light; and an estimation unit that estimates color of the subject based on a differential value between color information on the first image and the color information on the second image.

Abstract: Disclosed is a method for displaying a result of analysis performed on a specimen containing formed components. The method includes: obtaining, from each of the formed components, measurement values of at least three parameters; displaying a screen including a three-dimensional distribution chart in which the three parameters are used as axes and the formed components are represented by dots; and hiding specific dots on the three-dimensional distribution chart or changing a display format of the specific dots, according to an operation performed by a user.