Abstract: [Problem] To provide a method for detecting prostate cancer, the method having a higher degree of certainty than the PSA blood test and providing measurement values that correlate with risk classification. [Solution] This method for detecting prostate cancer is characterized in that: the method includes reacting fucose ?1?6 specific lectin and fucosylated PSA contained in a sample constituted of serum collected from a subject, and detecting the reacted lectin; and the pH in at least one step of the group consisting of the reaction step for reacting the fucosylated PSA and the lectin and processing steps thereafter is adjusted to above 8.5 and less than 11.0.

Abstract: According to one embodiment, a dialog system includes a processor. When a first sentence including one or more words is input by a user, the processor sets at least a part of the one or more words as a first query keyword. The processor selects, from a question-answer table including question-answer pairs, one or more of the question-answer pairs including the first query keyword. Each question-answer pair includes a question and an answer to the question. When a number of the selected question-answer pairs is 1, the processor outputs a first response indicating the answer. When the number is not less than a first threshold, the processor outputs a second response including first and second question keywords. The first question keyword is extracted from question keywords included in one of the pairs. The second question keyword is extracted from other question keywords included in another one of the pairs.

Abstract: According to one embodiment, a display control system includes a processor. The processor is capable of displaying a second sentence and at least a part of a first question-answer pair when accepting a first sentence including a first query keyword. The first sentence is input by a user. The first question-answer pair includes a first question and a first answer to the first question. The first question includes the first query keyword. The second sentence includes a first question keyword included in the first question. The processor is capable of displaying a word other than the first query keyword and the first question keyword in a first form, the first query keyword in a second form different from the first form, and the first question keyword in a third form different from the first form and the second form.

Abstract: According to one embodiment, an interactive system includes following units. The knowledge reference unit refers to a question-answering knowledge based on a result of analyzing an input sentence to acquire a candidate for an answer to the input sentence. The unknown keyword detection unit detects, from the input sentence, an unknown keyword. The related keyword estimation unit acquires, in response to the detection of the unknown keyword, one or more candidates for a related keyword having a meaning close to the unknown keyword from predetermined keywords. The response generation unit generates a response to the input sentence based on the one or more candidates for the related keyword when the unknown keyword is detected.

Abstract: [Problem] To provide a method for improving the detection sensitivity (S/N ratio) for conjugates of a glycoprotein and a sugar-binding compound in order to detect glycoproteins with a high degree of precision using a sugar-binding compound. [Solution] The glycoprotein assay method according to the present invention comprises reacting a glycoprotein with a sugar-binding compound having affinity with a glycan contained in the glycoprotein to detect the reacted sugar-binding compound, wherein a pH level is adjusted to an alkaline pH range of more than 8.5 to less than 11.0, in at least one step selected from among a group of steps consisting of the reaction step of the glycoprotein with the sugar-binding compound, and treatment steps subsequent thereto. The sugar-binding compound is preferably a sugar-binding protein.

Abstract: [Problem] To provide a method that increases the detection level of a reaction product generated through a reaction between a glycoprotein and a carbohydrate-binding compound in order to detect the glycoprotein with high precision. [Solution] A method for detecting a glycoprotein according to the present invention comprising the steps of: subjecting a sample containing the glycoprotein to a protease treatment; allowing the protease-treated glycoprotein to react with a sugar-binding compound having affinity with a glycan contained in the glycoprotein in order to obtain a reaction product between the glycoprotein and the sugar-binding compound; and detecting the reaction product. The sugar-binding compound is preferably a sugar-binding protein.

Abstract: According to one embodiment, a dialogue system includes a setting apparatus and a processing apparatus. The setting apparatus sets in advance a plurality of words that are in impossible combination relationships to each other. The processing apparatus acquires speech of a user, and when a speech recognition result of an object included in the speech includes a word combination included in the plurality of words that are in impossible combination relationships to each other, output a notification to the user that processing of the object cannot be carried out.

Abstract: To increase the yield of the separation process. To produce display devices formed through the separation process with higher mass productivity. A first layer is formed using a material including a resin or a resin precursor over a substrate. Then, first heat treatment is performed on the first layer, whereby a first resin layer including a residue of an oxydiphthalic acid is formed. Then, a layer to be separated is formed over the first resin layer. Then, the layer to be separated and the substrate are separated from each other. The first heat treatment is performed in an atmosphere containing oxygen.

Abstract: [Problem] To provide a method for detecting high-risk prostate cancer, for the purpose of providing useful information, such as necessity of biopsy, to a test-positive patient in a PSA test. [Solution] The method for detecting high-risk prostate cancer according to the present invention comprises reacting a PSA contained in a sample composed of urine collected from a human body which is suspected to be suffering from prostate cancer with (1) a fucose ?1?6 affinitive lectin which has a characteristic property that the lectin has affinity expressed by a binding constant of 1.0×104 M?1 or more (at 25° C.) for an ?1?6 fucose sugar chain No. 405. The fucose ?1?6 affinitive lectin is preferably (2) a fucose ?1?6 specific lectin which has a characteristic property that the lectin has a binding constant of 1.0×104 M?1 or less (at 25° C.) for a sugar chain No. 003 that does not contain ?1?6 fucose and a glycolipid-type sugar chain No. 909 that does not contain ?1?6 fucose.

Abstract: A micro-needle array unit includes a micro-needle array; a container which accommodates the micro-needle array and includes an accommodating portion having an opening and a protrusion that supports the outer peripheral surface of the micro-needle array, a deformation portion disposed on a side opposite to the opening and integrated with the accommodating portion, and a flange portion integrated with the accommodating portion and brought into contact with the skin; and a lid which seals the opening of the container, in which the deformation portion is deformed and the other surface of the micro-needle array is pressed due to an external force being applied in a direction of the opening, the micro-needle array deforms the protrusions and is pushed to the outside from the accommodating portion by the pressing of the other surface of the micro-needle array, and the deformation portion maintains the deformed state and presses the micro-needle array.

Abstract: To increase the yield of the separation process. To produce display devices formed through the separation process with higher mass productivity. A first layer is formed using a material including a resin or a resin precursor over a substrate. Then, first heat treatment is performed on the first layer, whereby a first resin layer including a residue of an oxydiphthalic acid is formed. Then, a layer to be separated is formed over the first resin layer. Then, the layer to be separated and the substrate are separated from each other. The first heat treatment is performed in an atmosphere containing oxygen.

Abstract: [Problem] To provide a signal enhancer that enhances a signal based on reaction between an ?1-6 fucose sugar chain and an ?1-6 fucose specific lectin bound thereto, a method for using the same, and use of the same. [Solution] A signal enhancer enhances a signal based on reaction between an ?1-6 fucose sugar chain and an ?1-6 fucose specific lectin bounded thereto, and is characterized by having, as an active ingredient, at least one selected from the group consisting of urea and thiourea. The final concentration of the urea is preferably 1-9 M and the final concentration of the thiourea is 0.1-1.5 M. Since the signal enhancer allows accurate measurement of an ?1-6 fucose sugar chain, the signal enhancer is greatly useful in detection and determination of a disease related to an ?1-6 fucose sugar chain and in academic study of an ?1-6 fucose sugar chain.

Abstract: According to one embodiment, a document search apparatus includes the following elements. The query word extraction unit extracts, from an input sentence, a word for use in a search as a query word. The intention estimation unit estimates a search intention based on the input sentence. The query generator acquires, from a search expression list, a search expression corresponding to the estimated search intention, acquires, from an additional query word list, an additional query word corresponding to a set of the acquired search expression and the extracted query word, and generates a query based on the extracted query word, the acquired additional query word, and the acquired search expression. The search unit searches for a document that matches the query.

Abstract: According to one embodiment, an interaction apparatus includes an acquirer, an estimator, an extractor, a selector and a controller. The acquirer acquires a text describing an intention of a user. The estimator estimates the intention from the text. The extractor extracts a keyword from the text. The selector selects a word having a part of speech from the text if the keyword having an attribute does not exist in the text when the keyword is to be assigned to a slot, the slot including information relating to the attribute and part of speech of a word necessary to execute a service corresponding to the intention. The controller assigns the selected word to the slot.

Abstract: Provided are a compound capable of becoming an organic transparent electrode, etc. One aspect of the present invention relates to an organic transparent electrode, which is configured from an organic molecule having a Brønsted acid functional group, electron-donating properties, and a ?-conjugated plane, characterized by being self-assembled. Another aspect of the present invention relates to the organic transparent electrode characterized in that the Brønsted acid functional group is one member selected from among a carboxylic acid functional group, a sulfonic acid functional group, a phosphonic acid functional group and a thiophosphonic acid functional group.

Abstract: A signal generating circuit includes an oscillator to produce an oscillation signal controlled in oscillating frequency by an analog control signal. The circuit includes: a digital phase detector detecting phase information of the oscillation signal and outputting digital phase information; a first differentiator differentiating the digital phase information and outputting digital frequency information; a comparator comparing a frequency setting code setting the oscillating frequency with the digital frequency information and outputting digital frequency error information; and a low-pass filter removing a high-frequency component of the digital frequency error information.

Abstract: A signal generator of an embodiment has an oscillator to generate an oscillation signal controlled in frequency by an analog control signal; a digital phase detector; a first differentiator; and a comparator outputting digital frequency error information. The generator includes a second differentiator differentiating the frequency setting code to generate a gain value and an inverse number of the gain value; a first multiplier multiplying the digital frequency error information by the gain value, a low-pass filter removing a high frequency component in a multiplication result, and a second multiplier multiplying an output of the low-pass filter by the inverse number. The generator includes a D/A converter converting a multiplication result into analog frequency error information, and an integrator converting the analog frequency error information into analog phase error information to output the analog phase error information as the analog control signal.

Abstract: Provided are a compound capable of becoming an organic transparent electrode, etc. One aspect of the present invention relates to an organic transparent electrode, which is configured from an organic molecule having a Brønsted acid functional group, electron-donating properties, and a ?-conjugated plane, characterized by being self-assembled. Another aspect of the present invention relates to the organic transparent electrode characterized in that the Brønsted acid functional group is one member selected from among a carboxylic acid functional group, a sulfonic acid functional group, a phosphonic acid functional group and a thiophosphonic acid functional group.

Abstract: A dialog generation apparatus includes a reception unit configured to receive a first text from a dialog partner, an information storage unit configured to store profile information specific to a person who can be the dialog partner and a fixed-pattern text associated with the person, a presentation unit configured to present the first text to a user, a speech recognition unit configured to perform speech recognition on speech the user has uttered about the first text presented to the user, and generate a speech recognition result showing the content of the speech, a generation unit configured to generate a second text from the profile information about the dialog partner, fixed-pattern text about the dialog partner, and the speech recognition result, and a transmission unit configured to transmit the second text to the dialog partner.