Abstract: A porous adsorption material is used to adsorb and remove an impurity from a solution containing a raw biopharmaceutical compound while suppressing clogging and is high in separation selectivity. The porous adsorption material used to adsorb and remove an impurity from a solution containing a raw biopharmaceutical compound includes a layer containing a nonionic polymer on at least one surface of the porous adsorption material.

Abstract: The present invention provides a decorative sheet with excellent flame retardance and high sharpness such that patterns are clearly visible and discoloration is suppressed. The present invention provides a decorative sheet characterized by comprising one or more thermoplastic resin layers selected from the group consisting of a transparent resin layer, a base material sheet, and a synthetic-resin backer layer, wherein (1) at least one of the thermoplastic resin layers contains a phosphazene-based flame retardant; and (2) the transparent resin layer and the base material sheet contain at least one resin selected from the group consisting of polyolefin-based resins and polyester-based resins.

Abstract: A tubular woven fabric is useful as a transport hose for a fluid or a powder, as a protective hose for linear bodies such as wires, cables and conduits, as a tubular filter, or as a base material of a vascular prosthesis. The tubular woven fabric includes warp yarns and weft yarns interwoven with each other, the tubular woven fabric having an outer diameter with a variation of within 10% along the warp direction and satisfying the formula: (L2?L1)/L1?0.1.

Abstract: The present invention provides a decorative sheet with excellent flame retardance and high sharpness such that patterns are clearly visible and discoloration is suppressed. The present invention provides a decorative sheet characterized by comprising one or more thermoplastic resin layers selected from the group consisting of a transparent resin layer, a base material sheet, and a synthetic-resin backer layer, wherein (1) at least one of the thermoplastic resin layers contains a metal phosphinate-based flame retardant; and (2) the transparent resin layer and the base material sheet contain at least one resin selected from the group consisting of polyolefin-based resins and polyester-based resins.

Abstract: A tubular woven fabric is useful as a transport hose for a fluid or a powder, as a protective hose for linear bodies such as wires, cables and conduits, as a tubular filter, or as a base material of a vascular prosthesis. The tubular woven fabric includes warp yarns and weft yarns interwoven with each other, the tubular woven fabric having an outer diameter with a variation of within 10% along the warp direction and satisfying the formula: (L2?L1)/L1?0.1.

Abstract: An antithrombogenic metallic material includes a metallic material whose surface is coated with a coating material, the coating material containing: a phosphonic acid derivative or a catechol derivative; a polymer containing, as a constituent monomer, a compound selected from the group consisting of alkyleneimines, vinylamines, allylamines, lysine, protamine, and diallyldimethylammonium chloride; and an anionic compound containing a sulfur atom and having anticoagulant activity; the polymer being covalently bound to the phosphonic acid derivative or the catechol derivative, the phosphonic acid derivative or the catechol derivative being bound to the metallic material through a phosphonic acid group or a catechol group thereof, wherein the abundance ratio of nitrogen atoms to the abundance of total atoms as measured by X-ray photoelectron spectroscopy (XPS) on the surface is 4.0 to 13.0 atomic percent.

Abstract: An artificial blood vessel is composed of a cylindrical multiple-woven fabric structure allowing only a small amount of blood leakage and can achieve both antithrombogenicity and cellular affinity. The artificial blood vessel includes a cylindrical fabric structure in which a cylindrical fabric whose inside contacts blood is arranged, wherein the cylindrical fabric is a fabric prepared by interlacing a plurality of warp yarns and a plurality of weft yarns with each other into a cylindrical shape; the warp yarns and the weft yarns constituting the cylindrical fabric include a multifilament yarn having a single yarn fineness of not more than 0.50 dtex, and are bound to an antithrombogenic material; the antithrombogenic material forms an antithrombogenic material layer having a thickness of 1 to 600 nm inside the cylindrical fabric; and the water permeability under conditions where a pressure of 16 kPa is applied to the inner surface is less than 300 mL/cm2/min.

Abstract: An antithrombogenic metallic material includes a metallic material whose surface is coated with a coating material, the coating material containing: a phosphonic acid derivative or a catechol derivative; a polymer containing, as a constituent monomer, a compound selected from the group consisting of alkyleneimines, vinylamines, allylamines, lysine, protamine, and diallyldimethylammonium chloride; and an anionic compound containing a sulfur atom and having anticoagulant activity; the polymer being covalently bound to the phosphonic acid derivative or the catechol derivative, the phosphonic acid derivative or the catechol derivative being bound to the metallic material through a phosphonic acid group or a catechol group thereof, wherein the abundance ratio of nitrogen atoms to the abundance of total atoms as measured by X-ray photoelectron spectroscopy (XPS) on the surface is 4.0 to 13.0 atomic percent.

Abstract: A double-weave vascular prosthesis includes an inner layer that contacts a flow of blood, and an outer layer in contact with the inner layer and having an inner layer-covering rate C (%) of 15%?C?75% defined by formula (1): C=[{(W1×D1+W2×D2)×25.4?W1×W2×D1 ×D2}/(25.4×25.4)]×100??(1), where D1 is a warp density (ends/25.4 mm) of the outer layer, D2 is a weft density (picks/25.4 mm) of the outer layer, W1 is an apparent width (mm) of a warp yarn of the outer layer, and W2 is an apparent width (mm) of a weft yarn of the outer layer, and the apparent width of each yarn is determined as a mean of measurement values for the widths of randomly selected five threads exposed on a surface of the woven structure.

Abstract: An artificial blood vessel includes a tubular woven fabric composed of a multifilament yarn A including a first polyester and a multifilament yarn B including a second polyester, and has an inner diameter of 8 mm or less and a layer thickness of 50 ?m or more and 250 ?m or less, wherein the multifilament yarn A has a single fiber fineness of 1.0 dtex or more and a total fineness of 33 dtex or less, the multifilament yarn B has a single fiber fineness of 0.08 dtex or less and a total fineness of 66 dtex or less, and the multifilament yarn B forms loops on an inner wall surface of the tubular woven fabric.

Abstract: An antithrombogenic material includes a coating material containing: a polymer containing, as a constituent monomer, a compound selected from the group consisting of alkyleneimines, vinylamines, allylamines, lysine, protamine and diallyldimethylammonium chloride; and an anionic compound containing a sulfur atom and having anticoagulant activity; and a base material whose surface is coated with the coating material; wherein the polymer is covalently bound to the base material; and an abundance ratio of nitrogen atoms to an abundance of total atoms as measured by X-ray photoelectron spectroscopy (XPS) on a surface of the base material is 6.0 to 12.0 atomic percent.

Abstract: A double-weave vascular prosthesis includes an inner layer that contacts a flow of blood, and an outer layer in contact with the inner layer and having an inner layer-covering rate C (%) of 15%?C?75% defined by formula (1): C=[{(W1×D1+W2×D2)×25.4?W1×W2×D1×D2}/(25.4×25.4)]×100 ??(1), where D1 is a warp density (ends/25.4 mm) of the outer layer, D2 is a weft density (picks/25.4 mm) of the outer layer, W1 is an apparent width (mm) of a warp yarn of the outer layer, and W2 is an apparent width (mm) of a weft yarn of the outer layer, and the apparent width of each yarn is determined as a mean of measurement values for the widths of randomly selected five threads exposed on a surface of the woven structure.

Abstract: An antithrombogenic material includes: a coating material containing a skeletal structure composed of a polymer, a skeletal structure composed of 4-(aminomethyl)benzenecarboxyimidamide or benzene amidine, and a skeletal structure composed of methoxybenzenesulfonic acid amide; and a base material whose surface is coated with the coating material; wherein the coating material is covalently bound to the base material, and the peak abundance ratio of the carbonyl-derived component in the total component of the C1s peak as measured by X-ray photoelectron spectroscopy on the surface is not less than 1.0 atomic percent.

Abstract: An artificial blood vessel is a tubular fabric including a fiber layer containing an ultrafine fiber(s) and an ultrafine fiber layer in the inside of the fiber layer, the ultrafine fiber layer being composed of an ultrafine fiber(s) having a fiber diameter(s) of not less than 10 nm and not more than 3 ?m, wherein a quaternary ammonium group-containing polymer having alkyl groups each of a carbon number 10 or less is covalently bound to the ultrafine fiber(s); heparin is ionically bound to the quaternary ammonium group-containing polymer; and the residual heparin activity after washing with physiological saline at 37° C. for 30 minutes is 20 mIU/cm2 or more.

Abstract: An artificial blood vessel is composed of a cylindrical multiple-woven fabric structure allowing only a small amount of blood leakage and can achieve both antithrombogenicity and cellular affinity. The artificial blood vessel includes a cylindrical fabric structure in which a cylindrical fabric whose inside contacts blood is arranged, wherein the cylindrical fabric is a fabric prepared by interlacing a plurality of warp yarns and a plurality of weft yarns with each other into a cylindrical shape; the warp yarns and the weft yarns constituting the cylindrical fabric include a multifilament yarn having a single yarn fineness of not more than 0.50 dtex, and are bound to an antithrombogenic material; the antithrombogenic material forms an antithrombogenic material layer having a thickness of 1 to 600 nm inside the cylindrical fabric; and the water permeability under conditions where a pressure of 16 kPa is applied to the inner surface is less than 300 mL/cm2/min.

Abstract: An antithrombogenic material includes a coating material containing: a polymer containing, as a constituent monomer, a compound selected from the group consisting of alkyleneimines, vinylamines, allylamines, lysine, protamine and diallyldimethylammonium chloride; and an anionic compound containing a sulfur atom and having anticoagulant activity; and a base material whose surface is coated with the coating material; wherein the polymer is covalently bound to the base material; and an abundance ratio of nitrogen atoms to an abundance of total atoms as measured by X-ray photoelectron spectroscopy (XPS) on a surface of the base material is 6.0 to 12.0 atomic percent.

Abstract: An artificial blood vessel is a tubular fabric including a fiber layer containing an ultrafine fiber(s) and an ultrafine fiber layer in the inside of the fiber layer, the ultrafine fiber layer being composed of an ultrafine fiber(s) having a fiber diameter(s) of not less than 10 nm and not more than 3 ?m, wherein a quaternary ammonium group-containing polymer having alkyl groups each of a carbon number 10 or less is covalently bound to the ultrafine fiber(s); heparin is ionically bound to the quaternary ammonium group-containing polymer; and the residual heparin activity after washing with physiological saline at 37° C. for 30 minutes is 20 mIU/cm2 or more.

Abstract: An artificial blood vessel promotes intimal formation after indwelling, and is capable of maintaining antithrombogenicity during the intimal formation and maintaining its patency for a long time. The artificial blood vessel is a tubular fabric including a fiber layer containing an ultrafine fiber(s) and an ultrafine fiber layer in the inside of the fiber layer, the ultrafine fiber layer being composed of an ultrafine fiber(s) having a fiber diameter(s) of 10 nm to 3 ?m, wherein an antithrombin agent having a polymer chain other than heparin is covalently bound to the ultrafine fiber via the polymer chain, and the thrombin activity inhibition rate on the fiber surface at 37° C. is not less than 60%.

Abstract: An artificial blood vessel includes a tubular woven fabric composed of a multifilament yarn A including a first polyester and a multifilament yarn B including a second polyester, and has an inner diameter of 8 mm or less and a layer thickness of 50 ?m or more and 250 ?m or less, wherein the multifilament yarn A has a single fiber fineness of 1.0 dtex or more and a total fineness of 33 dtex or less, the multifilament yarn B has a single fiber fineness of 0.08 dtex or less and a total fineness of 66 dtex or less, and the multifilament yarn B forms loops on an inner wall surface of the tubular woven fabric.

Abstract: An instrument captures free thrombi by inhibiting blood coagulation reaction at the stage of primary hemostasis, in which platelets are involved, and at the stage of coagulation thrombus formation, in which blood coagulation factors are involved, thereby securely capturing free thrombi and extending the available time of the instrument.