Patents by Inventor Yuker Wang

Yuker Wang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for synthesizing pools of probes
    Patent number: 11274327
    Abstract: Compositions, methods and kits are disclosed for synthesizing and amplifying pools of probes using precursor oligonucleotides. In some aspects the precursor is amplified and nicking enzymes are used to separate the full length probes from the amplification products. The methods enable the preparation of single stranded DNA probes of defined sequence and length that are suitable for use in target detection assays.
    Type: Grant
    Filed: October 17, 2019
    Date of Patent: March 15, 2022
    Inventors: Yuker Wang, Keith W. Jones, Ronald J. Sapolsky
  • METHODS FOR SYNTHESIZING POOLS OF PROBES
    Publication number: 20200109427
    Abstract: Compositions, methods and kits are disclosed for synthesizing and amplifying pools of probes using precursor oligonucleotides. In some aspects the precursor is amplified and nicking enzymes are used to separate the full length probes from the amplification products. The methods enable the preparation of single stranded DNA probes of defined sequence and length that are suitable for use in target detection assays.
    Type: Application
    Filed: October 17, 2019
    Publication date: April 9, 2020
    Inventors: Yuker Wang, Keith W. Jones, Ronald J. Sapolsky
  • Methods for synthesizing pools of probes
    Patent number: 10513722
    Abstract: Compositions, methods and kits are disclosed for synthesizing and amplifying pools of probes using precursor oligonucleotides. In some aspects the precursor is amplified and nicking enzymes are used to separate the full length probes from the amplification products. The methods enable the preparation of single stranded DNA probes of defined sequence and length that are suitable for use in target detection assays.
    Type: Grant
    Filed: May 6, 2016
    Date of Patent: December 24, 2019
    Inventors: Yuker Wang, Keith W. Jones, Ronald J. Sapolsky
  • Methods and kits for joining fragmented nucleic acids together
    Patent number: 10119161
    Abstract: Methods and kits for joining fragmented nucleic acid sequences together are provided, including performing an amplifying step including contacting a sample suspected of including a fragmented target nucleic acid with a pair of external primers and a pair of self-complementary internal primers, and generating a full length target nucleic acid. The methods can include performing an amplifying step, a hybridizing step, and a detecting step. Furthermore, kits are provided that are designed for the detection of a target nucleic acid sequence.
    Type: Grant
    Filed: December 10, 2015
    Date of Patent: November 6, 2018
    Assignee: Roche Molecular Systems, Inc.
    Inventors: Stephen G. Will, Yuker Wang
  • METHODS AND KITS FOR JOINING FRAGMENTED NUCLEIC ACIDS TOGETHER
    Publication number: 20170166953
    Abstract: Methods and kits for joining fragmented nucleic acid sequences together are provided, including performing an amplifying step including contacting a sample suspected of including a fragmented target nucleic acid with a pair of external primers and a pair of self-complementary internal primers, and generating a full length target nucleic acid. The methods can include performing an amplifying step, a hybridizing step, and a detecting step. Furthermore, kits are provided that are designed for the detection of a target nucleic acid sequence.
    Type: Application
    Filed: December 10, 2015
    Publication date: June 15, 2017
    Inventors: Stephen G. Will, Yuker Wang
  • METHODS FOR SYNTHESIZING POOLS OF PROBES
    Publication number: 20160348142
    Abstract: Compositions, methods and kits are disclosed for synthesizing and amplifying pools of probes using precursor oligonucleotides. In some aspects the precursor is amplified and nicking enzymes are used to separate the full length probes from the amplification products. The methods enable the preparation of single stranded DNA probes of defined sequence and length that are suitable for use in target detection assays.
    Type: Application
    Filed: May 6, 2016
    Publication date: December 1, 2016
    Inventors: Yuker Wang, Keith W. Jones, Ronald J. Sapolsky
  • Methods for synthesizing pools of probes
    Patent number: 9359640
    Abstract: Compositions, methods and kits are disclosed for synthesizing and amplifying pools of probes using precursor oligonucleotides. In some aspects the precursor is amplified and nicking enzymes are used to separate the full length probes from the amplification products. The methods enable the preparation of single stranded DNA probes of defined sequence and length that are suitable for use in target detection assays.
    Type: Grant
    Filed: May 7, 2014
    Date of Patent: June 7, 2016
    Assignee: Affymetrix, Inc.
    Inventors: Yuker Wang, Keith W. Jones, Ronald J. Sapolsky
  • METHODS FOR SYNTHESIZING POOLS OF PROBES
    Publication number: 20150004600
    Abstract: Compositions, methods and kits are disclosed for synthesizing and amplifying pools of probes using precursor oligonucleotides. In some aspects the precursor is amplified and nicking enzymes are used to separate the full length probes from the amplification products. The methods enable the preparation of single stranded DNA probes of defined sequence and length that are suitable for use in target detection assays.
    Type: Application
    Filed: May 7, 2014
    Publication date: January 1, 2015
    Applicant: Affymetrix, Inc.
    Inventors: Yuker Wang, Keith W. Jones, Ronald J. Sapolsky
  • Methods for synthesizing pools of probes
    Patent number: 8759036
    Abstract: Compositions, methods and kits are disclosed for synthesizing and amplifying pools of probes using precursor oligonucleotides. In some aspects the precursor is amplified and nicking enzymes are used to separate the full length probes from the amplification products. The methods enable the preparation of single stranded DNA probes of defined sequence and length that are suitable for use in target detection assays.
    Type: Grant
    Filed: March 21, 2012
    Date of Patent: June 24, 2014
    Assignee: Affymetrix, Inc.
    Inventors: Yuker Wang, Keith Jones, Ronald J. Sapolsky
  • Methods for Synthesizing Pools of Probes
    Publication number: 20130072390
    Abstract: Compositions, methods and kits are disclosed for synthesizing and amplifying pools of probes using precursor oligonucleotides. In some aspects the precursor is amplified and nicking enzymes are used to separate the full length probes from the amplification products. The methods enable the preparation of single stranded DNA probes of defined sequence and length that are suitable for use in target detection assays.
    Type: Application
    Filed: March 21, 2012
    Publication date: March 21, 2013
    Applicant: AFFYMETRIX, INC.
    Inventors: Yuker Wang, Keith Jones, Ronald J. Sapolsky