Patents by Inventor Yuki HAYAMI

Yuki HAYAMI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Anti-human CD69 antibody, and use thereof for medical purposes
    Patent number: 10865247
    Abstract: The present invention provides an antibody that specifically binds to human CD69, has an activity to suppress allergic inflammation, and has cross-reactivity with mouse CD69. In addition, the present invention provides an antibody having high binding affinity for human CD69 and an activity to suppress allergic inflammations. The antibody of the present invention can be a human antibody.
    Type: Grant
    Filed: February 20, 2020
    Date of Patent: December 15, 2020
    Assignees: GeneFrontier Corporation, National University Corporation Chiba University
    Inventors: Kanehisa Kojoh, Akira Miyakoshi, Shizue Katoh, Kumiko Tsuihiji, Yuki Hayami, Mikiko Nakamura, Toshinori Nakayama, Chiaki Iwamura
  • ANTI-HUMAN CD69 ANTIBODY, AND USE THEREOF FOR MEDICAL PURPOSES
    Publication number: 20200199235
    Abstract: The present invention provides an antibody that specifically binds to human CD69, has an activity to suppress allergic inflammation, and has cross-reactivity with mouse CD69. In addition, the present invention provides an antibody having high binding affinity for human CD69 and an activity to suppress allergic inflammations. The antibody of the present invention can be a human antibody.
    Type: Application
    Filed: February 20, 2020
    Publication date: June 25, 2020
    Applicants: GeneFrontier Corporation, National University Corporation Chiba University
    Inventors: Kanehisa Kojoh, Akira Miyakoshi, Shizue Katoh, Kumiko Tsuihiji, Yuki Hayami, Mikiko Nakamura, Toshinori Nakayama, Chiaki Iwamura
  • Anti-ADAM28 antibody for treating cancer
    Patent number: 10556967
    Abstract: The present invention provides an antibody that specifically binds to human ADAM28, inhibits enzyme activity of human ADAM28, and has an activity to suppress metastasis of a cancer cell that expresses human ADAM28. The antibody of the present invention can be a human antibody.
    Type: Grant
    Filed: November 16, 2017
    Date of Patent: February 11, 2020
    Assignees: GENEFRONTIER CORPORATION, KEIO UNIVERSITY
    Inventors: Akira Miyakoshi, Rena Matsumoto, Shizue Katoh, Yuki Hayami, Satsuki Mochizuki, Masayuki Shimoda, Yasunori Okada
  • ANTI-HUMAN CD69 ANTIBODY, AND USE THEREOF FOR MEDICAL PURPOSES
    Publication number: 20190233521
    Abstract: The present invention provides an antibody that specifically binds to human CD69, has an activity to suppress allergic inflammation, and has cross-reactivity with mouse CD69. In addition, the present invention provides an antibody having high binding affinity for human CD69 and an activity to suppress allergic inflammations. The antibody of the present invention can be a human antibody.
    Type: Application
    Filed: October 5, 2018
    Publication date: August 1, 2019
    Applicants: GeneFrontier Corporation, National University Corporation Chiba University
    Inventors: Kanehisa KOJOH, Akira MIYAKOSHI, Shizue KATOH, Kumiko TSUIHIJI, Yuki HAYAMI, Mikiko NAKAMURA, Toshinori NAKAYAMA, Chiaki IWAMURA
  • ANTI-ADAM28 ANTIBODY FOR TREATING CANCER
    Publication number: 20180155448
    Abstract: The present invention provides an antibody that specifically binds to human ADAM28, inhibits enzyme activity of human ADAM28, and has an activity to suppress metastasis of a cancer cell that expresses human ADAM28. The antibody of the present invention can be a human antibody.
    Type: Application
    Filed: November 16, 2017
    Publication date: June 7, 2018
    Applicants: GENEFRONTIER CORPORATION, KEIO UNIVERSITY
    Inventors: Akira MIYAKOSHI, Rena MATSUMOTO, Shizue KATOH, Yuki HAYAMI, Satsuki MOCHIZUKI, Masayuki SHIMODA, Yasunori OKADA
  • Anti-ADAM28 antibody for treating cancer
    Patent number: 9845364
    Abstract: The present invention provides an antibody that specifically binds to human ADAM28, inhibits enzyme activity of human ADAM28, and has an activity to suppress metastasis of a cancer cell that expresses human ADAM28. The antibody of the present invention can be a human antibody.
    Type: Grant
    Filed: October 1, 2013
    Date of Patent: December 19, 2017
    Assignees: GeneFrontier Corporation, Keio University
    Inventors: Akira Miyakoshi, Rena Matsumoto, Shizue Katoh, Yuki Hayami, Satsuki Mochizuki, Masayuki Shimoda, Yasunori Okada
  • Composition for synthesizing protein with reduced lipopolysaccharide contamination, method for producing protein using said composition
    Patent number: 9617533
    Abstract: According to the present invention, a composition possessing cell-free protein synthesis activity with reduced contaminating lipopolysaccharide, and a method for producing a protein using the same are provided. When ribosome display is performed using the composition and method for protein production of the present invention, the background that is caused by non-specific binding is reduced, so that a nucleic acid that encodes the desired polypeptide can be selected with high accuracy and high efficiency.
    Type: Grant
    Filed: September 25, 2015
    Date of Patent: April 11, 2017
    Assignees: GeneFrontier Corporation, The Univeristy of Tokyo
    Inventors: Takashi Kanamori, Yuki Hayami, Kanehisa Kojoh, Takuya Ueda, Kumiko Tsuihiji, Tomoe Fuse, Mikiko Nakamura, Shizue Kato
  • COMPOSITION FOR SYNTHESIZING PROTEIN WITH REDUCED LIPOPOLYSACCHARIDE CONTAMINATION, METHOD FOR PRODUCING PROTEIN USING SAID COMPOSITION
    Publication number: 20160010079
    Abstract: According to the present invention, a composition possessing cell-free protein synthesis activity with reduced contaminating lipopolysaccharide, and a method for producing a protein using the same are provided. When ribosome display is performed using the composition and method for protein production of the present invention, the background that is caused by non-specific binding is reduced, so that a nucleic acid that encodes the desired polypeptide can be selected with high accuracy and high efficiency.
    Type: Application
    Filed: September 25, 2015
    Publication date: January 14, 2016
    Inventors: Takashi KANAMORI, Yuki HAYAMI, Kanehisa KOJOH, Takuya UEDA, Kumiko TSUIHIJI, Tomoe FUSE, Mikiko NAKAMURA, Shizue KATO
  • Composition for synthesizing protein with reduced lipopolysaccharide contamination, method for producing protein using said composition
    Patent number: 9175327
    Abstract: According to the present invention, a composition possessing cell-free protein synthesis activity with reduced contaminating lipopolysaccharide, and a method for producing a protein using the same are provided. When ribosome display is performed using the composition and method for protein production of the present invention, the background that is caused by non-specific binding is reduced, so that a nucleic acid that encodes the desired polypeptide can be selected with high accuracy and high efficiency.
    Type: Grant
    Filed: May 3, 2011
    Date of Patent: November 3, 2015
    Assignees: GeneFrontier Corporation, The University of Tokyo
    Inventors: Takashi Kanamori, Yuki Hayami, Kanehisa Kojoh, Takuya Ueda, Kumiko Tsuihiji, Tomoe Fuse, Mikiko Nakamura, Shizue Kato
  • ANTI-ADAM28 ANTIBODY FOR TREATING CANCER
    Publication number: 20150274840
    Abstract: The present invention provides an antibody that specifically binds to human ADAM28, inhibits enzyme activity of human ADAM28, and has an activity to suppress metastasis of a cancer cell that expresses human ADAM28. The antibody of the present invention can be a human antibody.
    Type: Application
    Filed: October 1, 2013
    Publication date: October 1, 2015
    Inventors: Akira Miyakoshi, Rena Matsumoto, Shizue Katoh, Yuki Hayami, Satsuki Mochizuki, Masayuki Shimoda, Yasunori Okada
  • ANTI-HUMAN CD69 ANTIBODY, AND USE THEREOF FOR MEDICAL PURPOSES
    Publication number: 20150118237
    Abstract: The present invention provides an antibody that specifically binds to human CD69, has an activity to suppress allergic inflammation, and has cross-reactivity with mouse CD69. In addition, the present invention provides an antibody having high binding affinity for human CD69 and an activity to suppress allergic inflammations. The antibody of the present invention can be a human antibody.
    Type: Application
    Filed: April 23, 2013
    Publication date: April 30, 2015
    Inventors: Kanehisa Kojoh, Akira Miyakoshi, Shizue Katoh, Kumiko Tsuihiji, Yuki Hayami, Mikiko Nakamura, Toshinori Nakayama, Chiaki Iwamura
  • COMPOSITION FOR SYNTHESIZING PROTEIN WITH REDUCED LIPOPOLYSACCHARIDE CONTAMINATION, METHOD FOR PRODUCING PROTEIN USING SAID COMPOSITION
    Publication number: 20120231496
    Abstract: According to the present invention, a composition possessing cell-free protein synthesis activity with reduced contaminating lipopolysaccharide, and a method for producing a protein using the same are provided. When ribosome display is performed using the composition and method for protein production of the present invention, the background that is caused by non-specific binding is reduced, so that a nucleic acid that encodes the desired polypeptide can be selected with high accuracy and high efficiency.
    Type: Application
    Filed: May 3, 2011
    Publication date: September 13, 2012
    Applicants: THE UNIVERSITY OF TOKYO, GENEFRONTIER CORPORATION
    Inventors: Takashi KANAMORI, Yuki HAYAMI, Kanehisa KOJOH, Takuya UEDA, Kumiko TSUIHIJI, Tomoe FUSE, Mikiko NAKAMURA, Shizue KATO