Patents by Inventor Yukihiro Sugita

Yukihiro Sugita has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pigment epithelium-derived factor: characterization of its novel biological activity and sequences encoding and expressing the protein and methods of use
    Patent number: 5840686
    Abstract: Nucleic acids encoding the neurotrophic protein known as pigment epithelium-derived factor (PEDF), a truncated version of PEDF referred to as rPEDF, and equivalent proteins, vectors comprising such nucleic acids, host cells into which such vectors have been introduced, recombinant methods for producing PEDF, rPEDF, and equivalent proteins, the rPEDF protein and equivalent proteins of rPEDF and PEDF -BP, -BX and BA, and the PEDF protein produced by recombinant methodsEffects and uses of these variants on 1) neuronal differentiation (neurotrophic effect) 2) neuron survival (neuronotrophic effect) and 3) glial inhibition (gliastatic effect) are described.
    Type: Grant
    Filed: June 7, 1994
    Date of Patent: November 24, 1998
    Assignee: The United States of America as represented by the Department of Health and Human Services
    Inventors: Gerald J. Chader, Sofia Patricia Becerra, Joan P. Schwartz, Takayuki Taniwaki, Yukihiro Sugita