Patents by Inventor Yukio Dobashi

Yukio Dobashi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Genetically modified
    Patent number: 9902978
    Abstract: The present invention provides a means for producing butanol in butanol fermentation with high efficiency. The present invention relates to a genetically modified microorganism of Clostridium saccharoperbutylacetonicum, and a method for producing butanol using the microorganism.
    Type: Grant
    Filed: February 28, 2014
    Date of Patent: February 27, 2018
    Assignee: NIPPON SHOKUBAI CO., LTD.
    Inventors: Yukio Dobashi, Masaharu Mukoyama, Eita Ichige, Masahiro Nakanosho, Shunichi Nakayama
  • GENETICALLY MODIFIED CLOSTRIDIUM SACCHAROPERBUTYLACETONICUM
    Publication number: 20160053285
    Abstract: The present invention provides a means for producing butanol in butanol fermentation with high efficiency. The present invention relates to a genetically modified microorganism of Clostridium saccharoperbutylacetonicum, and a method for producing butanol using the microorganism.
    Type: Application
    Filed: February 28, 2014
    Publication date: February 25, 2016
    Inventors: Yukio DOBASHI, Masaharu MUKOYAMA, Eita ICHIGE, Masahiro NAKANOSHO, Shunichi NAKAYAMA
  • Method for enzymatically producing an optically active cyanohydrin
    Patent number: 7078225
    Abstract: The present invention relates to an enzyme reaction method which comprises performing an enzyme reaction, using an immobilized enzyme having a water content of 10% by weight or more as an enzyme and using an organic solvent substantially immiscible with water as a reaction solvent, under such conditions that a liquid phase forms a homogeneous system without phase separation although it is saturated with water or an aqueous buffer; a method for performing an enzyme reaction using an aldehyde compound as a substrate, which comprises removing a carboxylic acid compound contained in an aldehyde compound by subjecting the aldehyde compound to an alkaline treatment before starting the enzyme reaction; a method for performing an enzyme reaction using an aldehyde compound as a substrate, which comprises reducing a carboxylic acid compound content in the aldehyde compound to 0.
    Type: Grant
    Filed: June 1, 2001
    Date of Patent: July 18, 2006
    Assignee: Nippon Shokubai Co., Ltd.
    Inventors: Hisashi Semba, Yukio Dobashi
  • Enzyme reaction method and a method for enzymatically producing an optically active cyanohydrin
    Publication number: 20050089977
    Abstract: The present invention relates to an enzyme reaction method which comprises performing an enzyme reaction, using an immobilized enzyme having a water content of 10% by weight or more as an enzyme and using an organic solvent substantially immiscible with water as a reaction solvent, under such conditions that a liquid phase forms a homogeneous system without phase separation although it is saturated with water or an aqueous buffer; a method for performing an enzyme reaction using an aldehyde compound as a substrate, which comprises removing a carboxylic acid compound contained in an aldehyde compound by subjecting the aldehyde compound to an alkaline treatment before starting the enzyme reaction; a method for performing an enzyme reaction using an aldehyde compound as a substrate, which comprises reducing a carboxylic acid compound content in the aldehyde compound to 0.
    Type: Application
    Filed: November 15, 2004
    Publication date: April 28, 2005
    Inventors: Hisashi Semba, Yukio Dobashi
  • Method for producing ?-hydroxycarboxylic acid
    Patent number: 6864389
    Abstract: The present invention relates to: a method for producing ?-hydroxycarboxylic acid, which comprises hydrolyzing cyanohydrin in the presence of a hydrocarbon solvent; a method for producing optically active ?-hydroxycarboxylic acid, which comprises: producing optically active cyanohydrin by performing a reaction between a carbonyl compound and hydrogen cyanide, using a solvent comprising at least one organic solvent selected from a group consisting of an alcoholic solvent, an ester solvent, an ethereal solvent and a carboxylic solvent; removing said organic solvent from said reaction solvent; and hydrolyzing the remaining reaction mixture without isolating optically active cyanohydrin; a method for producing optically active ?-hydroxycarboxylic acid, which comprises hydrolyzing optically active cyanohydrin, using at most 10 equivalents of mineral acid relative to said optically active cyanohydrin under the condition that maximum temperature when reacting is 90° C.
    Type: Grant
    Filed: June 1, 2001
    Date of Patent: March 8, 2005
    Assignee: Nippon Shokubai Co., Ltd.
    Inventors: Norimasa Okuda, Hisashi Semba, Yukio Dobashi
  • Immobilized euphorbiaceae, poaceae or olacaeae s-hydroxynitrile lyase
    Patent number: 6709847
    Abstract: The present invention relates to a method for synthesizing optically active cyanohydrin. An immobilized enzyme is used in the invention, in which (S)-hydroxynitrile lyase is immobilized in a carrier comprising a porous inorganic material.
    Type: Grant
    Filed: January 12, 2001
    Date of Patent: March 23, 2004
    Assignee: Nippon Shokubai Co., Ltd.
    Inventors: Hisashi Semba, Yukio Dobashi
  • Method for producing alpha-hydroxycarboxylic acid
    Publication number: 20030171614
    Abstract: The present invention relates to:
    Type: Application
    Filed: June 1, 2001
    Publication date: September 11, 2003
    Applicant: Nippon Shokubai Co., Ltd.
    Inventors: Norimasa Okuda, Hisashi Semba, Yukio Dobashi
  • Method for synthesizing an optically active cyanohydrin
    Publication number: 20020064840
    Abstract: The present invention relates to a method for synthesizing optically active cyanohydrin. An immobilized enzyme is used in the invention, in which (S)-hydroxynitrile lyase is immobilized in a carrier comprising a porous inorganic material.
    Type: Application
    Filed: January 12, 2001
    Publication date: May 30, 2002
    Applicant: NIPPON SHOKUBAI CO., LTD.
    Inventors: Hisashi Semba, Yukio Dobashi
  • Enzyme reaction method and a method for enzymatically producing an optically active cyanohydrin
    Publication number: 20020006646
    Abstract: The present invention relates to an enzyme reaction method which comprises performing an enzyme reaction, using an immobilized enzyme having a water content of 10% by weight or more as an enzyme and using an organic solvent substantially immiscible with water as a reaction solvent, under such conditions that a liquid phase forms a homogeneous system without phase separation although it is saturated with water or an aqueous buffer; a method for performing an enzyme reaction using an aldehyde compound as a substrate, which comprises removing a carboxylic acid compound contained in an aldehyde compound by subjecting the aldehyde compound to an alkaline treatment before starting the enzyme reaction; a method for performing an enzyme reaction using an aldehyde compound as a substrate, which comprises reducing a carboxylic acid compound content in the aldehyde compound to 0.
    Type: Application
    Filed: June 1, 2001
    Publication date: January 17, 2002
    Applicant: Nippon Shokubai Co., Ltd.
    Inventors: Hisashi Semba, Yukio Dobashi
  • Method of producing 1-menthyl- &agr;-D-glucopyranoside
    Patent number: 6277602
    Abstract: A method of producing 1-menthyl-&agr;-D-glucopyranoside is provided, wherein microorganisms capable of producing 1-menthol glycoside from 1-menthol are added to sugars and 1-menthol. Bacteria selected from the group consisting of Xanthomonas species, Stenotrophomonas species and Arthrobacter species may be used as the microorganisms.
    Type: Grant
    Filed: November 30, 1998
    Date of Patent: August 21, 2001
    Assignee: Lotte Co., Ltd.
    Inventors: Shoji Usami, Kohtaro Kirimura, Hiroyuki Nakagawa, Yukio Dobashi, Masaaki Yoshiyama, Susumu Shimura, Yoshio Ito