Abstract: The present invention relates to a pharmaceutical composition for preventing or treating hypertrophic scars. The present inventors have found that the inhibition of expression of TXNDC5, PRRC1, S100A11, Galectin 1, Filamin A, eIF-5A, Annexin A2, and FABP5 can be a new target for improving and treating hypertrophic scars. In the present invention, TXNDC5-, PRRC1-, S100A11-, Galectin 1-, Filamin A-, eIF-5A-, Annexin A2-, and FABP5-specific siRNAs were constructed to determine the probability of treating the hypertrophic scars. As a result, the knockdown of the protein or a gene encoding the protein induces apoptosis in the hypertrophic scars and reduces collagen expression, which can be very useful in treating wounds.

Abstract: The present invention relates to a biomarker for predicting responsiveness to an anticancer agent and a use thereof, and more particularly, to: a marker composition for predicting responsiveness to atezolizumab, avelumab, or durvalumab, the marker composition comprising at least one gene selected from the group consisting of armadillo repeat-containing X-linked protein 1 (ARMCX1), serine/threonine-protein kinase D1 (PRKD1), and tyrosine kinase 2 (TYK2), or protein(s) encoded by the at least one gene; a composition for predicting responsiveness; a kit comprising the composition; and a method for providing information for predicting responsiveness. Gene markers according to the present invention are analyzed using patient-derived formalin-fixed paraffin-embedded tissues, and thus do not require the separate collection of samples, and the therefore convenient to analyze.

Abstract: There is provided an additive for secondary battery electrolyte, containing aluminum silicate. The aluminum silicate has a particle size of 200 nm to 20 ?m. The aluminum silicate has a mass ratio of 60 to 70 wt % of oxygen (O), 0.1 to 2.0 wt % of aluminum (Al), and 25 to 35 wt % of silicon (Si). The aluminum silicate has a surface area of 50 to 1,000 m2/g. The aluminum silicate has a pore size of 0.1 to 20 nm.

Abstract: An object of the present disclosure is to implement a coloring pattern with a low moisture content on an electrode substrate to thereby improve display reliability and lifetime as well as vivid colors. That is, since when the moisture content is 50 ppm or more, it may cause a reduction in luminance and lifetime due to pixel shrinkage, in order to minimize the moisture content after completion of the post-baking process, the generation of moisture in the panel state is minimized by generating sufficient heat and time in the post-baking step, by including the colorant of the present disclosure.

Abstract: There is provided an additive, containing magnesium silicate, for a secondary battery electrolyte and a preparation method therefor. The magnesium silicate has a mass ratio of 50 to 70 wt % of oxygen (O), 5 to 20 wt % of magnesium (Al), and 15 to 35 wt % of silicon (Si). The magnesium silicate has a surface area of 50 to 500 m2/g. The magnesium silicate has a pore size of 0.1 to 20 nm.

Abstract: A semiconductor memory device includes a memory bank arranged into first through nth split regions containing at least one memory cell sub-array within each split region, and first through nth global input/output (GIO) split lines electrically coupled to the first through nth split regions. First through n-lth connection control transistors are provided, which have gate terminals responsive to respective connection control signals. The first connection control transistor is configured to electrically short the first and second GIO split lines together when enabled by a corresponding connection control signal, and the n-1th connection control transistor is configured to electrically short the n-1th and nth GIO split lines together when enabled by a corresponding connection control signal. A GIO sense amplifier is provided, which is electrically coupled to the memory bank.

Abstract: There are provided a display device and a method of fabricating a display device. The display device includes: a substrate including a first surface and a second surface opposite to the first surface; a display element layer disposed on the first surface of the substrate, and a panel bottom member disposed on the second surface of the substrate. The panel bottom member includes: a light-blocking layer including a first base resin and light-blocking particles dispersed in the first base resin; a buffer layer including a second base resin; and a thermal protection member including a thermal protection material. A profile of the light-blocking layer conforms to a profile of the buffer layer in a plan view, and a surface of the light-blocking layer and a surface of the buffer layer are in direct contact with each other.

Abstract: The present disclosure provides an organic light emitting diode including a first electrode; a second electrode facing the first electrode; and an emitting material layer including a first compound and a second compound positioned between the first and second electrodes, wherein the first compound includes a hexagonal-ring moiety including one boron atom, one oxygen atom and four carbon atoms, and the second compound includes a hexagonal-ring moiety including one boron atom, one nitrogen atom and four carbon atoms, and an organic light emitting device including the organic light emitting diode.

Abstract: An apparatus for estimating a camera pose according to an embodiment of the present disclosure includes a similar image searcher, a clusterer, and an estimator. The similar image searcher searches for a plurality of images similar to an input image, from among a plurality of previously-stored images, based on the input image. The clusterer creates a cluster including at least some similar images meeting predetermined conditions, from among the plurality of similar images, based on viewpoint data tagged to each of the plurality of similar images. The estimator estimates a pose of a camera that has generated the input image, based on the cluster.

Abstract: A sensor integration module for detecting vehicle interior information and an operation method thereof are provided. The sensor integration module includes: a first sensor enabled based on first operation information and providing a sensing result as first sensing information; a second sensor enabled based on second operation information and providing a sensing result as second sensing information; a first communication device that transmits and receives information with electronic devices in a vehicle; and a controller that generates the first and second operation information for selectively enabling the first and second sensors based on information provided from the first communication device and provides the first communication device with the result determined based on the first and second sensing information.

Abstract: An electronic pen includes a signal generator, a power supply, and a resonance circuit. The signal generator is configured to generate a signal. The power supply is configured to supply power to the signal generator. The resonance circuit is configured to generate a current based on the signal and emit a magnetic field based on the current.

Abstract: Provided is a composition for surface treatment of a steel sheet, the composition having excellent resistance to an acid, such as sulfuric acid, and to a coated steel sheet to which the composition for surface treatment is applied, wherein the composition for surface treatment comprises 30-50% wt % of colloidal silica containing 5-20 nm-sized silica, 40-60% wt % of silane containing three or more alkoxy groups, 5-15 wt % of an acrylate-based organic monomer, 0.01-1 wt % of an acid, and 1-15 wt % of a solvent.

Abstract: Skin hydration is necessary to maintain the epidermal barrier, minimize adverse environmental influences, and reduce cell stress. Provided herein are compounds, such as compounds of Formula (I), and pharmaceutically and cosmetically acceptable salts thereof, and compositions, methods, and uses that may be used for skin hydration. Also reported herein is a scalable method for synthesizing compounds of Formula (I). The compounds provided herein are responsible for improved skin penetration and/or retention and are therefore useful for the treatment and/or prevention of various diseases, disorders, or conditions to protect human skin.

Abstract: A battery includes a housing defining a sealed chamber, a battery pack positioned within the sealed chamber, and a shape memory alloy member that is adapted to axially compress the volume within the sealed chamber to pressurize the sealed chamber to an optimal pressure, and to automatically allow axial expansion of the volume of the sealed chamber in response to an increase of the pressure within the sealed chamber to maintain the pressure within the sealed chamber at the optimal pressure.

Abstract: A cathode for a lithium secondary battery includes a cathode current collector, and a cathode active material layer formed on the cathode current collector. The cathode active material layer includes cathode active material particles. The cathode active material particles include a lithium metal oxide particle containing nickel and having a mole fraction of cobalt of 0.02 or less among all elements except lithium and oxygen.

Abstract: A semiconductor memory device is provided which is capable of adaptively controlling bias and a method of operating the same. The semiconductor memory device includes: a memory cell area including a plurality of first transistors to which a first bias voltage is applied; and a peripheral circuit area which overlaps the memory cell area in a first direction and includes a plurality of second transistors to which a second bias voltage controlled differently from the first bias voltage is applied.

Abstract: Integrated circuit devices and methods of forming the same are provided. The methods may include providing a substrate structure including a substrate, a bottom insulator and a semiconductor region between the substrate and the bottom insulator, the semiconductor region extending in a first direction; forming first and second preliminary transistor structures on the bottom insulator, wherein and the bottom insulator may include first and second portions that the first and second preliminary transistor structures respectively overlap, and a third portion between the first and second portions; replacing the third portion of the bottom insulator with a bottom semiconductor layer; forming a source/drain region between the first and second preliminary transistor structures; replacing the substrate and the semiconductor region with a backside insulator; forming a power contact in the backside insulator, wherein the source/drain region may overlap the power contact; and forming a power rail.

Abstract: A display device including a display panel having a folding area and a bending area, a support member disposed on a surface of the display panel and including a plurality of openings formed in the folding area, an elastic member disposed on a surface of the support member and overlapping the openings in the folding area, and a first adhesive member disposed between the support member and the elastic member.

Abstract: The present invention relates to a botulinum toxin freeze-dried dosage form composition storable for a long time, comprising botulinum toxin, protamine sulfate, an isotonic agent and a buffer agent, and a botulinum toxin freeze-dried dosage form according to the present invention lowers the inactivation rate of botulinum toxin during freeze-drying, can maintain the stability of botulinum toxin for longer than a conventional botulinum toxin freeze-dried dosage form, forms a uniform particle size so that the effect exhibited at the site of administration is the same and can prevent the side effect in which an excessive toxin administration effect is exhibited only at some sites.

Abstract: Determining a semiconductor device manufacturing parameter may include determining an EPM (electrical measurement parameters) group that has a correlation in a baseline EPM dataset including EPMs of a device manufactured under a baseline condition, deriving principal components (PCs) corresponding to main correlation axes between EPMs in the EPM group, deriving a PC-based dataset including a baseline PC dataset and a conditional split PC dataset by converting the baseline EPM dataset and a conditional split EPM dataset measured from devices manufactured under conditional splits into a PC domain, determining, using the PC-based dataset, respective PCs which are effectively changed by the conditional splits, obtaining split variation information of the conditional splits, extracting an optimal point capable of optimizing a figure of merit of a semiconductor device within a range of the PC-based dataset, and deriving information for process feedback for realizing the optimal point using the split variation infor