Abstract: Disclosed herein are oral care compositions comprising: a) one or more pyrophosphate compounds, wherein the total concentration of pyrophosphate compounds in the composition is 0.5 wt % to 1.5 wt %, based on the weight of the oral care composition; b) one or more thickening gums, wherein the total concentration of thickening gums in the composition is 1.25 wt % to 1.6 wt %, based on the weight of the oral care composition; and c) a metal ion source.

Abstract: The disclosure is directed to processes and methods of reducing bloating and breakage of containers and packaging that house oral care compositions. Also contemplated are products and formulations that are produced or obtained from the processes and methods described herein.

Abstract: A topical preparation containing vitamin K1 and a preparation method thereof are provided. The topical preparation includes the following components in weight percentage: 0.01-5% of vitamin K1, 0.1-25% of a transdermal enhancer and 70-99% of a matrix for the topical preparation. The transdermal enhancer is composed of urea, menthol and Eucalyptus oil in a mass ratio of (5-6):(2-3):(1-3). The topical preparation containing vitamin K1 can be used to treat moderate and severe skin toxicity caused by anti-tumor drugs related to epidermal growth factor receptor (EGFR), can effectively treat diseases such as acne-like rash, pruritus, red swelling, dry skin and mucositis caused by EGFR-related anti-tumor drugs, and can ensure the continued treatment with anti-EGFR targeting drugs. It can increase the possibility of vitamin K1 reaching focus sites in the dermal layer through the stratum corneum, and can rapidly alleviate moderate and severe skin diseases caused by EGFR-related anti-tumor drugs.

Abstract: A method for performing machine learning process performed by at least one computing device, the method including: continuously collecting prediction data; continuously collecting real results of the prediction data; generating updated training samples based on the collected prediction data and corresponding real results thereof and continuously obtaining updated machine learning models by using the updated training samples, according to a configured model updating scheme; and selecting an online machine learning model for providing an online prediction service from among the machine learning models according to a configured model application scheme, and in response to a prediction service request including prediction data, providing a predicted result for the prediction data included in the prediction service request by using the online machine learning model.

Abstract: Described herein are oral care compositions comprising—in relevant part—an effective amount of inulin. Methods of making and using these compositions are also described.

Abstract: This invention relates to oral care compositions comprising a basic amino acid or salt thereof, a sugar alcohol, and an optional fluoride source, wherein the oral care composition is in an amount effective to inhibit a pH reduction consequent to bacterial glycolysis in the oral cavity; and to methods of using and of making these compositions.

Abstract: An oral care composition and methods for the same are disclosed herein. The oral care composition may include an orally acceptable vehicle, an anionic surfactant, and a nonionic surfactant. The anionic surfactant may include a C6-C18 fatty acid glutamate or a salt thereof, and the nonionic surfactant may include a C6-C18 alkyl polyglucoside. A weight ratio of the nonionic surfactant to the anionic surfactant may be from about 0.25:1 to about 9:1, or from about 1.8:1 to about 2.2:1.

Abstract: The invention provides oral care compositions, for example a dentifrice or mouthwash, comprising zinc phosphate, wherein the zinc phosphate is added to the dentifrice or mouthwash as a preformed salt; as well as methods of making and using the same.

Abstract: This invention relates to oral care compositions with improved foaming properties which comprise a basic amino acid, an abrasive and a taurate surfactant, as well as to methods of using these compositions. Optionally, the oral care compositions further comprise an alkyl polyglucoside.

Abstract: An oral care composition and methods for the same are disclosed herein. The oral care composition may include an orally acceptable vehicle, an anionic surfactant, and a nonionic surfactant. The anionic surfactant may include a C6-C18 fatty acid glutamate or a salt thereof, and the nonionic surfactant may include a C6-C18 alkyl polyglucoside. A weight ratio of the nonionic surfactant to the anionic surfactant may be from about 0.25:1 to about 9:1, or from about 1.8:1 to about 2.2:1.

Abstract: A topical preparation containing vitamin K1 and a preparation method thereof are provided. The topical preparation includes the following components in weight percentage: 0.01-5% of vitamin K1, 0.1-25% of a transdermal enhancer and 70-99% of a matrix for the topical preparation. The transdermal enhancer is composed of urea, menthol and eucalyptus oil in a mass ratio of (5-6):(2-3):(1-3). The topical preparation containing vitamin K1 can be used to treat moderate and severe skin toxicity caused by anti-tumor drugs related to epidermal growth factor receptor (EGFR), can effectively treat diseases such as acne-like rash, pruritus, red swelling, dry skin and mucositis caused by EGFR-related anti-tumor drugs, and can ensure the continued treatment with anti-EGFR targeting drugs. It can increase the possibility of vitamin K1 reaching focus sites in the dermal layer through the stratum corneum, and can rapidly alleviate moderate and severe skin diseases caused by EGFR-related anti-tumor drugs.

Abstract: According to one aspect of the invention, there is provided a method of forming a film with a lenticular lens array, the method comprising providing a substrate; providing a mold having a plurality of nano-scale to micro-scale cavities that form the lenticular lens array on the substrate; having the mold contact the substrate; and forming the lenticular lens array by allowing portions of the substrate to partially fill the plurality of cavities.

Abstract: The present invention provides compositions and methods to enhance cutaneous wound healing in subjects afflicted with, or at risk for, a pulmonary infection and/or a pulmonary injury. More specifically, the embodiments of the present invention relate to using fibrin carrier as a vehicle to topically deliver one or more chemokine onto a cutaneous wound so as to accelerate wound healing.

Abstract: The present invention relates to oral composition and the method of preparation and use of such composition for inhibiting, reducing, and/or disrupting oral biofilm. The composition comprises a stabilizing matrix, a cationic biocide, and a peroxide source.

Abstract: This invention relates to oral care compositions, for example comprising a salt of a basic amino acid having a pH in solution of less than 7.5, an abrasive having a pH in solution of less than 7.5, and a fluoride ion source, and an acid selected from the group consisting of: a carboxylic acid (e.g., citric acid, lactic acid, glycolic acid, acetic acid, succinic acid, or fumaric acid), and an inorganic acid, wherein the inorganic acid is not phosphoric acid or sulfuric acid (e.g.

Abstract: Oral care compositions and methods for the same are disclosed. The oral care composition may include an orally acceptable vehicle, and one or more surfactants. The one or more surfactants may include an N-alkyl-N-acylglucamine. The oral care composition may further include an amino acid and one or more abrasives. The method for treating or reducing dentinal hypersensitivity may include contacting the oral care composition with surfaces of the teeth.

Abstract: An oral care composition and methods for the same are disclosed herein. The oral care composition may include an orally acceptable vehicle, an anionic surfactant, and a nonionic surfactant. The anionic surfactant may include a C6-C18 fatty acid glutamate or a salt thereof, and the nonionic surfactant may include a C6-C18 alkyl polyglucoside. A weight ratio of the nonionic surfactant to the anionic surfactant may be from about 0.25:1 to about 9:1, or from about 1.8:1 to about 2.2:1.

Abstract: Disclosed herein is an oral care composition comprising at least one abrasive and a charcoal agent, wherein the charcoal agent is present in an amount ranging from about 0.02% to about 4% by weight based on the total weight of the oral care composition. Further disclosed herein are methods of making an oral care composition comprising at least one abrasive and at least one charcoal agent wherein the charcoal agent is present in an amount ranging from about 0.02% to about 4% by weight based on the total weight of the oral care composition, as well as methods of whitening teeth and/or cleaning the teeth comprising contacting the teeth with an oral care composition as disclosed herein.