Abstract: The invention provides a hydrophilized polydiorganosiloxane vinylic crosslinker which comprises (1) a polydiorganosiloxane polymer chain comprising dimethylsiloxane units and hydrophilized siloxane units each having one methyl substituent and one monovalent C4-C40 organic radical substituent having two to six hydroxyl groups, wherein the molar ratio of the hydrophilized siloxane units to the dimethylsiloxane units is from about 0.035 to about 0.15, and (2) two terminal (meth)acryloyl groups. The hydrophilized polydiorganosiloxane vinylic crosslinker has a number average molecular weight of from about 3000 Daltons to about 80,000 Daltons. The present invention is also related to a silicone hydrogel contact lens, which comprises repeating units derived from a hydrophilized polydiorganosiloxane vinylic crosslinker of the invention.

Abstract: The invention provides a method for imaging and thickness determination of coatings on coated contact lenses. The method comprises selectively staining a negatively-charged-groups-containing coating over the lens body of a coated contact lens by immersing the coated contact lens in an aqueous solution comprising a fluorescently-labeled polycationic polymer and having a pH of from about 6.5 to 8.0; orthogonally cutting the selectively-stained coated contact lens; and determining the thickness of the coating on the coated contact lens. In addition, the invention provides a method for selecting a candidate coating material comprising negatively charged groups for applying a coating with a desired thickness onto silicone hydrogel contact lenses and for optimizing a coating process for producing coated silicone hydrogel contact lenses with a desired thickness coating thereon.

Abstract: Disclosed herein is a waterborne polyurethane-epoxy resin-based primer composition and its preparation method. Further disclosed herein is a primer layer obtained from curing the waterborne polyurethane-epoxy resin-based primer composition on substrates as well as a method of curing the primer composition on substrates.

Abstract: The present invention discloses a 400 MPa corrosion-resistant steel bar and a production method thereof. The steel bar includes the following chemical ingredients: 9.5-10.4% of Cr, 1.0-1.2% of Mo, 0.3-0.6% of Mn, 0.01-1% of Ni, 0.01-0.5% of Cu, at most 0.014% of C, at most 0.004% of N, 0.01-0.05% of Nb, 0.2-0.6% of Si, and the balance of Fe, where Cr+Mo+0.5Mn+0.35Ni+0.25Cu is 11.1-12.2%, and C+N+0.3Si+Mn+1.8Nb is 0.4-0.8%.

Abstract: A display panel driving method, a display device and a driving device are provided. The method obtains a standard driving voltage value of a target pixel when a subject display content is being displayed and a target compression unit corresponding to the target pixel, determines a target compensation curve parameter from compressed de-Mura data corresponding to the target compression unit according to the standard driving voltage value, determines an effective driving voltage value of the target pixel when the subject content is being displayed according to a position information where the target pixel is in the target compression unit and the target compensation curve parameter, and drives the display panel according to the effective driving voltage. This method could correctly identify the corresponding decompression data and thus the decompressed data could be close to the actual data. This raises the decompression accuracy of decompressing the de-Mura data.

Abstract: The present application relates to a protein-drug conjugate, containing an antigen binding protein portion and a drug conjugate portion. The antigen binding protein portion comprises one or more antigen binding fragments, and at least two linker peptides are directly or indirectly connected to the antigen binding fragments. The two linker peptides can each independently contain a first cysteine Cys1 and a second cysteine Cys2. The drug conjugate portion is covalently bonded on Cys1. The present application further relates to a preparation method for the protein-drug conjugate, and a use for the protein-drug conjugate in preventing or treating tumors or other diseases.

Abstract: The present application discloses a display device brightness compensation look-up table obtaining method. The method includes a parameter reading step, an initial grayscale brightness detection step, a compensation region brightness detection step, a compensation data obtaining step, and a compensation look-up table generation step. The above method solves a technical issue that conventional demura technologies cannot uniform brightness of the display panel to result in poor quality of the display panel.

Abstract: Provided are an antigen binding protein capable of binding to PD-1 and a fusion protein thereof, and corresponding preparation method therefor and the use thereof. The fusion protein is capable of targeting PD-1 and CD73.

Abstract: Described herein is a method for producing photochromic contact lenses, in particular, photochromic silicone hydrogel contact lenses. The method comprises a step of cast molding of a lens-forming composition including an iniferter to form an unprocessed contact lens having iniferter moieties covalently incorporated into its polymer matrix and a step of iniferter-induced graft-polymerization of a photochromic vinylic monomer to the polymer matrix only in its central region which is circular and concentric with the central axis of the unprocessed contact lens. The obtained photochromic contact lens has a central pupillary region that only can undergo a reversible color change upon exposure to UV/HEVL-radiation.

Abstract: This application discloses a signal processing method and an apparatus. The method includes: A transmit device generates a PPDU, and sends the PPDU; and a receive device receives the PPDU, and processes M sequences carried in the PPDU. The PPDU shown in this application includes a first field, the first field is used for carrying M sequences, the M sequences correspond to M space-time streams, one sequence corresponds to one space-time stream, and M is a positive integer. According to the method provided in this application, sequence sending efficiency can be effectively improved.

Abstract: The present invention generally relates to inherently wettable silicone hydrogel contact lenses having relatively high oxygen permeability, relatively high equilibrium water content and relatively low elastic modulus. The present invention is also related to a method for making such inherently wettable silicone hydrogel contact lenses.

Abstract: The invention is generally related to an insert for being embedded in a silicone hydrogel contact lens. The insert is made of a crosslinked materials which are rigid in dry state at room temperature (from about 22° C. to about 26° C.), have a high oxygen permeability and a high refractive index in fully hydrated state, and can become softer at a temperature great than 32° C. Such materials are useful for making inserts in embedded contact lenses for correcting corneal astigmatism, presbyopia, and color blindness lenses and for imparting photochromic characteristics to the lenses. The invention is also related to a method for making embedded silicone hydrogel contact lenses comprising an insert of the invention therein and to embedded silicone hydrogel contact lenses comprising an insert of the invention therein.

Abstract: An unit narrow board glue application device and method suitable for high-frequency hot pressing of solid wood edge glued panel is disclosed, including a transverse chain feeding device, a longitudinal roller feeding device and a gluing device. The transverse chain feeding device includes a fixed chain transport mechanism and a movable chain transport mechanism. The longitudinal roller feeding device includes the lifting power roller assembly, the longitudinal feed roller assembly and the pneumatic compression roller assemblies. The gluing device includes a glue pump, a glue application head, and a pneumatic slide table. The front end face of the hollow structure glue application head has a number of small round holes for glue liquid discharge and horizontal glue guiding grooves. The disclosure has a high degree of automation, can give full play to the efficiency of the high-frequency hot press, and is conducive to the intelligent manufacturing of solid wood furniture.

Abstract: A virtual device management system for creating and implementing virtual devices and associated methods are provided herein. The system presents to a user a list of devices available for combining to create the virtual device. When the system receives from the user a selection of two or more devices that the user wishes to combine to create the virtual device, the system presents to the user a list of available functions that can be performed by the virtual device based on the selected devices. The system then receives from the user a selection of one or more functions and configures the virtual device to perform the selected functions. The system can also be configured to present, via a user interface via a mobile application running on a user device, a plurality of virtual devices with predetermined functionalities that are created by detecting the various connected devices within an IoT network.

Abstract: The invention relates to a pad printing instrument comprising an ink supply system capable of control the temperature, viscosity and colorant concentration of an ink in an ink cup. Such controls are achieved by continuously adding and mixing a cold ink having a composition identical to the ink in the ink cup but having a lower temperature. The continuous addition of a small amount of a cold ink into the ink cup could compensate heat generated by the friction between the ink cup and a cliché and could minimize the evaporation of a diluent in the ink and change in the concentration of colorants in the ink and ink viscosity. The invention also relates to use of a pad printing instrument comprising an ink supply system of the invention for producing colored hydrogel or silicone hydrogel contact lenses.

Abstract: Methods and systems provide for providing video-based chapter generation for a communication session. In one embodiment, the system receives a transcript and video content of a communication session between participants, the transcript including timestamps for a number of utterances associated with speaking participants; processes the video content to extract one or more pieces of textual content visible within the frames of the video content; segments frames of the video content into a number of contiguous topic segments; determines a title for each topic segment from one or more of: the transcript, and the extracted textual content; assigns a category label for each topic segment from a prespecified list of category labels; and transmits, to one or more client devices, the list of topic segments with determined title and assigned category label for each of the merged topic segments.

Abstract: The invention is generally related to a method for producing, in a relatively efficient and consistent manner, embedded or hybrid silicone hydrogel contact lenses, and also to unprocessed embedded or hybrid silicone hydrogel contact lenses, according to conventional cast-molding technologies. A method of the invention involve use of a polymeric non-reactive diluent in preparing a polymerizable composition for forming the silicone hydrogel material of the unprocessed embedded or hybrid silicone hydrogel contact lens, which is cast-molded with a lens mold. The unprocessed cast-molded embedded or hybrid silicone hydrogel contact lens has no or a minimal water-swelling degree, so that lens distortion or delamination during the hydration of the unprocessed embedded or hybrid silicone hydrogel contact lens.

Abstract: A method of making an electrical connector which includes an insulative housing having a tongue with an upper and lower surfaces, a plurality of contacts having respective contacting portions exposed to the upper and lower surfaces of the tongue and having two outermost upper or lower contacts, and a shielding member situated between the upper and lower surfaces of the tongue and overlapping the two outermost upper or lower contacts along a vertical direction perpendicular to the upper and lower surfaces of the tongue is characterized by the steps of: forming the plurality of contacts from a first carrier; forming the shielding member from a second carrier to have the two discrete shielding plates; stacking the first carrier and the second carrier; and molding the plurality of contacts and the two discrete shielding plates with an insulator in one shot.

Abstract: Described herein is a method for producing a contact lens comprising a central photochromic zone that has a diameter of about 13 mm or less and is concentric with the central axis of the contact lens. The method comprises: applying, in the center of the molding surface of a male mold half, a drop (having a volume of about 5 ?L or less) of a first polymerizable fluid composition containing at least one photochromic compound and a relatively-high molecular weight polysiloxane vinylic crosslinker for increasing the viscosity and adhesion on the molding surface of the male mold half; dosing a second polymerizable fluid composition in a female mold hald; closing the female mold hald with the male mold half with the drop thereon to form a molding assembly; and curing the second polymerizable fluid composition and the drop of the first polymerizable fluid composition in the molding assembly.

Abstract: The present disclosure provides a method in a Network Exposure Function, NEF, entity for facilitating provision of Location Service, LCS. The method includes: receiving from an Application Function, AF, entity a monitoring event subscription message requesting for location reporting of a current location of a terminal device; transmitting a monitoring event configuration request to configure location reporting on an Access and Mobility Management Function, AMF, entity; receiving from the AMF entity a monitoring event indication containing an indication of a cell in which the terminal device is currently located; transmitting to an LCS node a request for the current location of the terminal device; receiving from the LCS node the current location of the terminal device; and transmitting to the AF entity a monitoring event subscription response message containing the current location of the terminal device.