Patents by Inventor Yunbing Wang

Yunbing Wang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Bioabsorbable scaffold with particles providing delayed acceleration of degradation
    Patent number: 8709070
    Abstract: Methods of controlling the degradation profile of a biodegradable stent scaffolding are disclosed. A bioabsorbable scaffold having a plurality of particles incorporated into the scaffolding that accelerate the absorption of the scaffolding after an induction time during degradation is disclosed.
    Type: Grant
    Filed: May 10, 2011
    Date of Patent: April 29, 2014
    Assignee: Abbott Cardiovascular Systems Inc.
    Inventors: Yunbing Wang, James Oberhauser
  • POST ELECTRON BEAM CONDITIONING OF POLYMERIC MEDICAL DEVICES
    Publication number: 20140110885
    Abstract: Methods are disclosed for conditioning a polymeric stent after sterilization, and/or after crimping and before packaging, such that the properties of the polymeric stent fall within a narrower range of values. The stent is exposed to a controlled temperature at or above ambient for a period of time after radiation sterilization and/or after crimping and before sterilization. As a result, the polymeric stent properties, particularly radial strength and number-average molecular weight of the polymer of the polymeric stent, fall within a narrower range.
    Type: Application
    Filed: December 23, 2013
    Publication date: April 24, 2014
    Applicant: Abbott Cardiovascular Systems Inc.
    Inventors: Yunbing Wang, Xiao Ma, Fuh-Wei Tang, Ni Ding
  • Biodegradable stent with enhanced fracture toughness
    Publication number: 20140114394
    Abstract: Stents and methods of manufacturing a stents with enhanced fracture toughness are disclosed.
    Type: Application
    Filed: October 9, 2013
    Publication date: April 24, 2014
    Applicant: Abbott Cardiovascular Systems Inc.
    Inventors: David C. Gale, Bin Huang, Timothy A. Limon, Vincent J. Gueriguian, Anthony J. Abbate, Klaus Kleine, Stephen Schaible, Jonathan P. Durcan, Thierry Glauser, Bethany Steichen, James Oberhauser, Manish Gada, Lothar Kleiner, Mary Beth Kossuth, Yunbing Wang, Daniel Castro, David Wrolstad
  • Method to minimize chain scission and monomer generation in processing of poly(L-lactide) stent
    Patent number: 8703038
    Abstract: Methods of fabricating an implantable medical devices such as stents made from biodegradable polymers are disclosed that reduce or minimize chain scission and monomer generation during processing steps. The method includes processing a poly(L-lactide) resin having an number average molecular weight between 150 to 200 kD in an extruder in a molten state. A poly(L-lactide) tube is formed from the processed resin and a stent is fabricated from the tube. The number average molecular weight of the poly(L-lactide) of the stent after sterilization is 70 to 100 kD.
    Type: Grant
    Filed: July 19, 2013
    Date of Patent: April 22, 2014
    Assignee: Abbott Cardiovascular Systems Inc.
    Inventors: Yunbing Wang, James Oberhauser
  • Biodegradable stent with enhanced fracture toughness
    Publication number: 20140107762
    Abstract: Stents and methods of manufacturing a stents with enhanced fracture toughness are disclosed.
    Type: Application
    Filed: October 9, 2013
    Publication date: April 17, 2014
    Applicant: Abbott Cardiovascular Systems Inc.
    Inventors: David C. Gale, Bin Huang, Timothy A. Limon, Vincent J. Gueriguian, Anthony J. Abbate, Klaus Kleine, Stephen Schaible, Jonathan P. Durcan, Thierry Glauser, Bethany Steichen, James Oberhauser, Manish Gada, Lothar Kleiner, Mary Beth Kossuth, Yunbing Wang, Daniel Castro, David Wrolstad
  • Biodegradable stent with enhanced fracture toughness
    Publication number: 20140107761
    Abstract: Stents and methods of manufacturing a stents with enhanced fracture toughness are disclosed.
    Type: Application
    Filed: October 9, 2013
    Publication date: April 17, 2014
    Applicant: Abbott Cardiovascular Systems Inc.
    Inventors: David C. Gale, Bin Huang, Timothy A. Limon, Vincent J. Gueriguian, Anthony J. Abbate, Klaus Kleine, Stephen Schaible, Jonathan P. Durcan, Thierry Glauser, Bethany Steichen, James Oberhauser, Manish Gada, Lothar Kleiner, Mary Beth Kossuth, Yunbing Wang, Daniel Castro, David Wrolstad
  • Method of Uniform Crimping and Expansion of Medical Devices
    Publication number: 20140096357
    Abstract: A medical device-includes a scaffold crimped to a catheter having an expansion balloon. The scaffold is crimped to the balloon by a process that includes one or more balloon pressurization steps. The balloon pressurization steps are selected to enhance scaffold retention to the balloon, maintain a relatively uniform arrangement of balloon folds about the inner surface of the crimped scaffold so that the scaffold expands in a uniform manner when the balloon is inflated, and to avoid any possible over-stretching of balloon material.
    Type: Application
    Filed: October 4, 2012
    Publication date: April 10, 2014
    Applicant: Abbott Cardiovascular Systems Inc.
    Inventor: Yunbing Wang
  • IMPLANTABLE MEDICAL DEVICE MADE FROM AN AMORPHOUS OR VERY LOW CRYSTALLINITY POLYMER CONSTRUCT
    Publication number: 20140084515
    Abstract: Methods of fabricating a polymeric implantable device with improved fracture toughness through annealing, nucleating agents, or both are disclosed herein. A polymeric construct that is completely amorphous or that has a very low crystallinity is annealed with no or substantially no crystal growth to increase nucleation density. Alternatively, the polymer construct includes nucleating agent. The crystallinity of the polymer construct is increased with a high nucleation density through an increase in temperature, deformation, or both. An implantable medical device, such as a stent, can be fabricated from the polymer construct after the increase in crystallinity.
    Type: Application
    Filed: September 16, 2013
    Publication date: March 27, 2014
    Applicant: Abbott Cardiovascular Systems Inc.
    Inventors: Yunbing Wang, Lothar W. Kleiner
  • IMPLANTABLE MEDICAL DEVICES FABRICATED FROM BRANCHED POLYMERS
    Publication number: 20140081417
    Abstract: Stent scaffolds comprising branched biocompatible polymers are disclosed.
    Type: Application
    Filed: November 19, 2013
    Publication date: March 20, 2014
    Applicant: Abbott Cardiovascular Systems Inc.
    Inventors: Yunbing Wang, David C. Gale, Bin Huang, Mikael O. Trollsas, Thierry Glauser, Florian Ludwig
  • STENT RETAINED ON A BALLOON CATHETER
    Publication number: 20140052235
    Abstract: A balloon is inflated from a collapsed configuration, then deflated. A polymeric stem is then disposed over the deflated balloon and the stent crimped to the balloon.
    Type: Application
    Filed: October 21, 2013
    Publication date: February 20, 2014
    Applicant: Abbott Cardiovascular Systems Inc.
    Inventors: Yunbing Wang, Gregory Kilinski, Luis Vazquez
  • IMPLANTABLE MEDICAL DEVICES FABRICATED FROM BRANCHED POLYMERS
    Publication number: 20140046006
    Abstract: Implantable medical devices fabricated from branched polymers are disclosed.
    Type: Application
    Filed: July 12, 2013
    Publication date: February 13, 2014
    Applicant: Abbott Cardiovascular Systems Inc.
    Inventors: Yunbing Wang, David C. Gale, Bin Huang, Mikael O. Trollsas, Thierry Glauser, Florian Ludwig
  • METHODS TO INCREASE FRACTURE RESISTANCE OF A DRUG-ELUTING MEDICAL DEVICE
    Publication number: 20140044860
    Abstract: Methods for increasing the fracture resistance of a polymer stent's drug-polymer coating and scaffolding including applying a coating and crimping using techniques that increase the resistance to fracture in the coating layer and scaffolding and scaffolding.
    Type: Application
    Filed: October 15, 2013
    Publication date: February 13, 2014
    Applicant: Abbott Cardiovascular Systems Inc.
    Inventors: Dan Castro, Yunbing Wang
  • METHODS FOR CRIMPING A POLYMERIC STENT ONTO A DELIVERY BALLOON
    Publication number: 20140033506
    Abstract: A medical device—includes a polymer stent crimped to a catheter having an expansion balloon. The stent is crimped to the balloon by a process that includes heating the stent to a temperature below the polymer's glass transition temperature to improve stent retention without adversely affecting the mechanical characteristics of the stent when later deployed to support a body lumen.
    Type: Application
    Filed: September 19, 2013
    Publication date: February 6, 2014
    Applicant: Abbott Cardiovascular Systems Inc.
    Inventors: Kevin F. Jow, Arlene Sucy Yang, Yunbing Wang, Kathleen W. Yan
  • BIOABSORBABLE SCAFFOLDS MADE FROM COMPOSITES
    Publication number: 20140039603
    Abstract: Bioabsorbable scaffolds made at least in part of a poly(L-lactide)-based composite are disclosed. The composite includes poly(4-hydroxybutyrate) or poly(L-lactide)-b-polycaprolactone block copolymer, which increases the fracture toughness or fracture resistance of the scaffold. The composite can further include bioceramic particles, L-lactide monomer, or both dispersed throughout the composite. The bioceramic particles improve the radial strength and stiffness of the scaffold. The L-lactide monomer is used to control the absorption rate of the scaffold.
    Type: Application
    Filed: September 30, 2013
    Publication date: February 6, 2014
    Applicant: Abbott Cardiovascular Systems Inc.
    Inventor: Yunbing Wang
  • SHAPE MEMORY BIORESORBABLE POLYMER PERIPHERAL SCAFFOLDS
    Publication number: 20140025161
    Abstract: Bioabsorbable scaffolds having high crush recoverability, high fracture resistance, and reduced or no recoil due to self expanding properties at physiological conditions are disclosed. The scaffolds are made from a random copolymer of PLLA and a rubbery polymer such as polycaprolactone.
    Type: Application
    Filed: July 23, 2012
    Publication date: January 23, 2014
    Applicant: ABBOTT CARDIOVASCULAR SYSTEMS INC.
    Inventors: John S. Stankus, Hugh Zhao, Mikael Trollsas, Syed Faiyaz Ahmed Hossainy, Michael H. Ngo, Yunbing Wang, Benny Serna
  • POLYMER-BIOCERAMIC COMPOSITE IMPLANTABLE MEDICAL DEVICE WITH DIFFERENT TYPES OF BIOCERAMIC PARTICLES
    Publication number: 20140018907
    Abstract: Implantable medical devices fabricated from polymer/bioceramic composites with different types of bioceramic particles are disclosed.
    Type: Application
    Filed: July 1, 2013
    Publication date: January 16, 2014
    Applicant: Abbott Cardiovascular Systems Inc.
    Inventors: Yunbing WANG, David C. GALE, Syed F.A. HOSSAINY
  • REDUCING CRIMPING DAMAGE TO A POLYMER SCAFFOLD
    Publication number: 20140013575
    Abstract: A medical device includes a polymer scaffold crimped to a catheter having an expansion balloon. The scaffold is crimped to the catheter by a multi-step process for increasing scaffold-catheter yield following a crimping sequence. Damage reduction during a crimping sequence includes modifying blades of a crimper, adopting a multi-step crimping sequence, and inflating a supporting balloon to support the scaffold during crimping.
    Type: Application
    Filed: September 11, 2013
    Publication date: January 16, 2014
    Applicant: Abbott Cardiovascular Systems Inc.
    Inventors: Yunbing Wang, Luis Vazquez, Hung T. Nguyen, Scott H. Mueller, Kathleen Yan
  • REDUCING CRIMPING DAMAGE TO A POLYMER SCAFFOLD
    Publication number: 20140008007
    Abstract: A medical device includes a polymer scaffold crimped to a catheter having an expansion balloon. The scaffold is crimped to the catheter by a multi-step process for increasing scaffold-catheter yield following a crimping sequence. Damage reduction during a crimping sequence includes modifying blades of a crimper, adopting a multi-step crimping sequence, and inflating a supporting balloon to support the scaffold during crimping.
    Type: Application
    Filed: September 11, 2013
    Publication date: January 9, 2014
    Applicant: Abbott Cardiovascular Systems Inc.
    Inventors: Yunbing Wang, Luis Vazquez, Hung T. Nguyen, Scott H. Mueller, Kathleen Yan
  • STENTS INCLUDING POLY(L-LACTIDE) FORMULATIONS THAT MINIMIZE MOLECULAR WEIGHT DROP DURING PROCESSING
    Publication number: 20140012365
    Abstract: A stent scaffolding including a polymer formulation comprising PLLA and polymandelide is disclosed. The polymandelide reduces the molecular weight drop during processing, particularly during sterilization. The stent scaffolding can further include one or more additional stabilizing agents that additionally reduce the molecular weight drop during processing.
    Type: Application
    Filed: September 9, 2013
    Publication date: January 9, 2014
    Applicant: Abbott Cardiovascular Systems Inc.
    Inventors: Byron Lambert, Yunbing Wang, James Oberhauser
  • Post electron beam conditioning of polymeric medical devices
    Patent number: 8613880
    Abstract: Methods are disclosed for conditioning a polymeric stent after sterilization, and/or after crimping and before packaging, such that the properties of the polymeric stent fall within a narrower range of values. The stent is exposed to a controlled temperature at or above ambient for a period of time after radiation sterilization and/or after crimping and before sterilization. As a result, the polymeric stent properties, particularly radial strength and number-average molecular weight of the polymer of the polymeric stent, fall within a narrower range.
    Type: Grant
    Filed: April 25, 2011
    Date of Patent: December 24, 2013
    Assignee: Abbott Cardiovascular Systems Inc.
    Inventors: Yunbing Wang, Xiao Ma, Fuh-Wei Tang, Ni Ding