Patents by Inventor Yunde Zhao

Yunde Zhao has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • System for site-specific modification of ALS gene using CRISPR-Cas9 system for production of herbicide-resistant rice and use of same
    Patent number: 10988774
    Abstract: The present invention discloses a system for site-specific modification of ALS gene by a CRISPR-Cas9 system to produce herbicide-resistant rice, and uses thereof. The system for site-specific modification in a plant genome of the present invention comprises a vector for site-specific modification in a plant genome and a donor DNA; wherein the vector for site-specific modification in a plant genome comprises a Cas9 protein expression cassette, gRNA expression cassettes and a donor DNA; the gRNA expression cassettes encode two gRNAs targeting two target sites of a target DNA of a plant of interest, respectively; the target DNA has a fragment to be site-specifically modified which is positioned between the two target site.
    Type: Grant
    Filed: March 25, 2016
    Date of Patent: April 27, 2021
    Assignee: INSTITUTE OF CROP SCIENCES, CHINESE ACADEMY OF AGRICULTURAL SCIENCES
    Inventors: LanQin Xia, YongWei Sun, YunDe Zhao, YouZhi Ma, ChuanYin Wu, Xin Zhang
  • GENE EDITING AND TRANSGENE FREE MUTANT PLANTS
    Publication number: 20200048646
    Abstract: The disclosure provides compositions and methods to transform and edit the genome of plants and to measure heritable genetic modifications.
    Type: Application
    Filed: March 7, 2018
    Publication date: February 13, 2020
    Inventor: Yunde Zhao
  • SYSTEM FOR SITE-SPECIFIC MODIFICATION OF ALS GENE USING CRISPR-CAS9 SYSTEM FOR PRODUCTION OF HERBICIDE-RESISTANT RICE AND USE OF SAME
    Publication number: 20190085356
    Abstract: The present invention discloses a system for site-specific modification of ALS gene by a CRISPR-Cas9 system to produce herbicide-resistant rice, and uses thereof. The system for site-specific modification in a plant genome of the present invention comprises a vector for site-specific modification in a plant genome and a donor DNA; wherein the vector for site-specific modification in a plant genome comprises a Cas9 protein expression cassette, gRNA expression cassettes and a donor DNA; the gRNA expression cassettes encode two gRNAs targeting two target sites of a target DNA of a plant of interest, respectively; the target DNA has a fragment to be site-specifically modified which is positioned between the two target site.
    Type: Application
    Filed: March 25, 2016
    Publication date: March 21, 2019
    Inventors: LanQin XIA, YongWei SUN, YunDe ZHAO, YouZhi MA, ChuanYin WU, Xin ZHANG
  • Expression of flavin-containing monoxygenases in plants
    Patent number: 6455760
    Abstract: The present invention provides methods for using enhanced expression of nucleotide sequences encoding a flavin-containing monooxygenase (FMO) and suitable homologs thereof, to elicit desired traits, study biochemical pathways, and oxidize xenobiotics in plants.
    Type: Grant
    Filed: November 16, 2000
    Date of Patent: September 24, 2002
    Assignee: The Salk Institute of Biological Studies
    Inventors: Yunde Zhao, Joanne Chory, Christian Fankhauser, Detlef Weigel, John Cashman