Abstract: A compound, as represented by formula I, as a TLR7 agonist, a method for preparing the compound, and the use of the compound in treating diseases mediated by the TLR7 agonist are provided. Studies on the activity of a human-derived receptor, a TLR7 agonist, show that compounds have a strong agonistic effect on the human-derived receptor, TLR7, and can be used as a foreground compound for treating diseases mediated by the TLR7 agonist.

Abstract: A centralized cooperative positioning method includes: caching measurements of nodes in multiple time slices up to the current time slice; calculating location information of the nodes in the multiple time slices to obtain trajectory of the nodes in the multiple time slices; performing initial state estimations of the nodes based on measurements of a single time slice; and using the initial state estimations as initial solution values, performing the joint time-space processing on the measurements of the nodes in the multiple time slices based on trajectory constraints, to obtain a state estimation of each node at the current time slice, in which the state estimation includes an estimated value of a location of the node.

Abstract: A secondary battery comprises a secondary battery assembly, the secondary battery assembly comprises an electric cell assembly, a transfer conductor and an insulation plate, wherein the electric cell assembly comprises at least two electric cells arranged side by side, and each electric cell has a tab extending from the top surface of the electric cell. The transfer conductor is provided with a transfer conductor tab assembly part. The insulation plate is located between the electric cell assembly and the transfer conductor, and the insulation plate is provided with a plate tab matching part, wherein, the folded tab passes through the plate tab matching part of the base plate and the transfer conductor tab assembly part in turn, and then is welded with the transfer conductor. The secondary battery of the application features short tabs, good battery performance, high safety, high assembly efficiency and low cost.

Abstract: The top cover structure for a secondary battery includes: an insulating plate, provided with a lower through hole penetrating up and down; a top cover plate located on the top of the insulating plate, provided with an upper through hole interconnected with the lower through hole and penetrating up and down; a conductor, passing through the upper through hole and the lower through hole and fixedly connecting with the top cover plate and the insulating plate, and the conductor is provided with an intersecting hole penetrating through the conductor. An intersecting hole penetrating through the conductor is provided on the conductor, so that the conductor can not only connect and conduct the secondary battery from the outside to the inside of the secondary battery, but also can conveniently inject or replenish liquid into the secondary battery through the intersecting hole, thereby improving the production efficiency of the secondary battery.

Abstract: A top cover for a power battery including a top cover plate, a first post, a first fastener, a second post, a first sealing member, and an insulation plate.

Abstract: A centralized cooperative positioning method includes: caching measurements of nodes in multiple time slices up to the current time slice; calculating location information of the nodes in the multiple time slices to obtain trajectory of the nodes in the multiple time slices; performing initial state estimations of the nodes based on measurements of a single time slice; and using the initial state estimations as initial solution values, performing the joint time-space processing on the measurements of the nodes in the multiple time slices based on trajectory constraints, to obtain a state estimation of each node at the current time slice, in which the state estimation includes an estimated value of a location of the node.

Abstract: The present disclosure provides a method and an electronic device for obtaining location information. Available measurement of a target node and multi-hop nodes in multiple consecutive time slices is obtained. A prediction is performed on the unavailable measurement due to the transmission delay to obtain prediction information. Location information of these nodes in the multiple time slices is obtained based on state variables of the target node and multi-hop nodes in the current time slice and mobility constraints, for reconstructing the trajectory information of these nodes. State information of these nodes in the current time slice is initially estimated based on available measurement to obtain initial state estimation in the current time slice. State estimation of these nodes in the current time slice is obtained by jointly processing the available measurement and the prediction information based on the trajectory constraints and the initial state estimation.

Abstract: The present disclosure provides a method and an electronic device for obtaining location information. Available measurement of a target node and multi-hop nodes in multiple consecutive time slices is obtained. A prediction is performed on the unavailable measurement due to the transmission delay to obtain prediction information. Location information of these nodes in the multiple time slices is obtained based on state variables of the target node and multi-hop nodes in the current time slice and mobility constraints, for reconstructing the trajectory information of these nodes. State information of these nodes in the current time slice is initially estimated based on available measurement to obtain initial state estimation in the current time slice. State estimation of these nodes in the current time slice is obtained by jointly processing the available measurement and the prediction information based on the trajectory constraints and the initial state estimation.

Abstract: A pixel driving circuit, a driving method, an organic light emitting display panel and a display device, including: a data writing module, a storage module, at least one first light emitting device, a first driving module corresponding to the respective first light emitting device one-to-one, at least one second light emitting device, and a second driving module corresponding to the respective second light emitting device one-to-one.

Abstract: The invention discloses a pixel driving circuit, a driving method, an organic light emitting display panel and a display device. The pixel driving circuit comprises a data writing module (1), a memory module (2), at least one first light emitting device (D1), a first driving module (3) which corresponds to the various first light emitting devices (D1) one by one, at least one second light emitting device (D2) and a second driving module (4) which corresponds to the various second light emitting devices (D2) one by one. Through mutual cooperation of each module, the voltage of a node can be switched between a positive value and a negative value by virtue of a simple structure, so that performances of the first driving module (3) and the second driving module (4) are recovered, and then the influence on the stability and the service life of the display panel due to performance offset of the first driving module (3) and the second driving module (4) is relieved.