Abstract: A system and method for mental workload measurement and analysis are disclosed, which measure time intervals between saccades in eye movements. These intervals, called Inter Saccadic Intervals (ISI), characterize different levels of mental workload during operator performance, such as for MRO (Operator of Robot Manipulator). The device can include sensors for measuring oculometric potentials from the human face, an amplifier for amplifying measured potentials, an analog-to-digital (A/D) converter for generating digital output signals relating to the measured potentials, and a digital computer for continually measuring the electrooculogramic potential, extracting the saccades, calculating ISIS, and then determining quantitative criteria of mental workload based on the ISIS.