Abstract: The present invention is directed to the combination therapy of cancer with a BRAF inhibitor and a MEK inhibitor, as well as uses and pharmaceutical compositions thereof.

Abstract: A support of a sole structure includes a base disposed in a middle region in a foot width direction and having an upper surface which follows a plantar surface of a wearer's foot, and upper and lower supports continuous with a side portion of the base on a medial side in the foot width direction. The upper support has an upper surface that is continuous with the side portion of the base such that the upper surface of the upper support, together with the upper surface of the base, follows the plantar surface. The lower support is continuous with the side portion of the base so as to be located under the upper support, and has a corrugated shape having peaks and valleys alternating with each other in a longitudinal direction along the side portion of the base.

Abstract: Disclosed is a sole structure for shoes, which includes a lower midsole. The lower midsole includes a medial-side midsole portion which extends in a medial side portion of a heel region supporting a heel of a wearer's foot, and a lateral-side midsole portion which extends in a lateral side portion of the heel region, and which faces, and is spaced apart from, the medial-side midsole portion in a foot width direction. The lateral-side midsole portion includes supports which are arranged adjacent to each other in a longitudinal direction with a gap interposed therebetween and which support the wearer's heel, and a coupling portion which is provided in the gap, and couples the adjacent supports to each other to reduce displacement or twist in the foot width direction occurring between the adjacent supports.

Abstract: A support of a sole structure includes a base disposed in a middle region in a foot width direction and having an upper surface which follows a plantar surface of a wearer's foot, and upper and lower supports continuous with a side portion of the base on a medial side in the foot width direction. The upper support has an upper surface that is continuous with the side portion of the base such that the upper surface of the upper support, together with the upper surface of the base, follows the plantar surface. The lower support is continuous with the side portion of the base so as to be located under the upper support, and has a corrugated shape having peaks and valleys alternating with each other in a longitudinal direction along the side portion of the base.

Abstract: Disclosed is a sole structure for shoes, which includes a lower midsole. The lower midsole includes a medial-side midsole portion which extends in a medial side portion of a heel region supporting a heel of a wearer's foot, and a lateral-side midsole portion which extends in a lateral side portion of the heel region, and which faces, and is spaced apart from, the medial-side midsole portion in a foot width direction. The lateral-side midsole portion includes supports which are arranged adjacent to each other in a longitudinal direction with a gap interposed therebetween and which support the wearer's heel, and a coupling portion which is provided in the gap, and couples the adjacent supports to each other to reduce displacement or twist in the foot width direction occurring between the adjacent supports.

Abstract: A method for manufacturing a magnetic head, includes forming, on a non-magnetic film, a main magnetic pole film with a body portion and a write magnetic pole portion continuous with the body portion, and etching the non-magnetic film such that an undercut is formed around the body portion and beneath the write magnetic pole portion. The undercut penetrates beneath the write magnetic pole portion in a track width direction. The method includes wet etching the non-magnetic film beneath the main magnetic pole film at the undercut, the undercut being at least partially filled with an organic filler. The method also includes, after removal of the organic filler, covering at least both sides of the write magnetic pole portion with a magnetic gap film, and forming a write shield film adjacent to the magnetic gap film. The undercut forms a hollow in the non-magnetic film underlying the write magnetic pole portion.

Abstract: A camera system includes an image capture section, a positioning section that performs positioning and a control section that controls the positioning section. The control section causes at least one operation of the positioning section and the control section to transition to a power saving mode, while the image capture section continues a predetermined operation.

Abstract: The present invention relates to a method for manufacturing a perpendicular recording magnetic head, more particularly, to a method for manufacturing a main magnetic pole film with a wrap-around structure. After the main magnetic pole film with a body portion of a large plane area and a write magnetic pole portion continuous with the body portion and elongated in a plane area is formed on one face of a non-magnetic film, the one face of the non-magnetic film is etched. Then, it also includes the step of further etching the one face of the non-magnetic film with an undercut, which is caused by the etching around the body portion and beneath the write magnetic pole portion, being at least partially filling with an organic filler.