Patents by Inventor Yutaka Mukaida

Yutaka Mukaida has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5140020
    Abstract: Disclosed herein are a derivative of dihydroxybenzamide represented by the formula(I): ##STR1## wherein (1) R.sup.1 represents a hydrogen atom or a lower alkyl group and R.sup.2 represents a straight chain-alkyl group of 4 to 12 carbon atoms, a branched chain-alkyl group of 4 to 12 carbon atoms, a cyclo-alkyl group of 4 to 12 carbon atoms, ##STR2## wherein n is an integer of 1 to 6, or a pyridyl group which is substituted or unsubstituted, or (2) R.sup.1 and R.sup.2 are cyclized to make a heterocycle containing amino group represented by the formula ##STR3## wherein X represents a nitrogen atom or a methine and Y represents a hydrogen atom, an alkyl group of 1 to 6 carbon atoms or a phenyl group, and a pharmaceutical composition containing the same.
    Type: Grant
    Filed: June 20, 1991
    Date of Patent: August 18, 1992
    Assignee: Kureha Kagatu Kogyo Kabushiki Kaisha
    Inventors: Hitoshi Takita, Sakuo Noda, Yutaka Mukaida, Kazuyoshi Inada, Mari Toji, Fumihiko Kimura, Toyohiko Nitta, Kohju Watanabe, Kiyonori Umekawa, Hidetoshi Kobayashi
  • Patent number: 4997850
    Abstract: The present invention discloses a method for treating a patient suffering from osteoarthritis comprising administering a physiologically effective amount of pharmaceutical composition containing at least one compound, as an active ingredient, represented by the formula (I): ##STR1## wherein R represents a hydrogen atom or an acyl group; X represents a CHO group, a COOH group, a physiologically acceptable salt thereof or a CH(OR').sub.2 group wherein R' represents an acyl group.
    Type: Grant
    Filed: April 12, 1990
    Date of Patent: March 5, 1991
    Assignee: Kureha Kagaku Kogyo Kabushiki Kaisha
    Inventors: Fumihiko Kimura, Yutaka Mukaida, Koju Watanabe
  • Patent number: 4841097
    Abstract: Disclosed herein are dialkanoyloxybenzylidene dialkanoate represented by the formula ##STR1## wherein X.sup.1 and X.sup.2 represent respectively alkanoyloxy group and a pharmaceutical composition in dosage unit form which comprises a dosage effective for the treatment of inflammatory disease of the dialkanoyloxybenzylidene dialkanoate as an active ingredient thereof.
    Type: Grant
    Filed: April 13, 1988
    Date of Patent: June 20, 1989
    Assignee: Kureha Kagaku Kogyo Kabushiki Kaisha
    Inventors: Hitoshi Takita, Fumihiko Kimura, Sakuo Noda, Yutaka Mukaida, Toyohiko Nitta, Hidetoshi Kobayashi
  • Patent number: 4758591
    Abstract: Disclosed herein are dialkanoyloxybenzylidene dialkanoate represented by the formula, ##STR1## wherein X.sup.1 and X.sup.2 represent respectively alkanoyloxy group and a pharmaceutical composition in dosage unit form which comprises a dosage effective for the treatment of inflammatory disease of the dialkanoyloxybenzylidene dialkanoate as an active ingredient thereof.
    Type: Grant
    Filed: December 13, 1984
    Date of Patent: July 19, 1988
    Assignee: Kureha Kagaku Kogyo Kabushiki Kaisha
    Inventors: Hitoshi Takita, Fumihiko Kimura, Sakuo Noda, Yutaka Mukaida, Toyohiko Nitta
  • Patent number: 4725598
    Abstract: Disclosed herein are a derivative of dihydroxybenzamide represented by the formula(I): ##STR1## wherein (1) R.sup.1 represents a hydrogen atom or a lower alkyl group and R.sup.2 represents a straight chain-alkyl group of 4 to 12 carbon atoms, a branched chain-alkyl group of 4 to 12 carbon atoms, a cyclo-alkyl group of 4 to 12 carbon atoms, ##STR2## wherein n is an integer of 1 to 6, or a pyridyl group which is substituted or unsubstituted, or (2) R.sup.1 and R.sup.2 are cyclized to make a heterocycle containing amino group represented by the formula ##STR3## wherein X represents a nitrogen atom or a methine and Y represents a hydrogen atom, an alkyl group of 1 to 6 carbon atoms or a phenyl group, and a pharmaceutical composition containing the same.
    Type: Grant
    Filed: December 8, 1986
    Date of Patent: February 16, 1988
    Assignee: Kureha Kagaku Kogyo Kabushiki Kaisha
    Inventors: Hitoshi Takita, Sakuo Noda, Yutaka Mukaida, Kazuyoshi Inada, Mari Toji, Fumihiko Kimura, Toyohiko Nitta, Kohju Watanabe, Kiyonori Umekawa, Kobayashi, Hidetoshi
  • Patent number: 4578404
    Abstract: Disclosed herein are a pharmaceutical composition for treating nephritis, comprising at least one compound selected from the group consisting of the derivatives of N-(dihdyroxybenzylidene)amino acid, represented by the formula (I): ##STR1## wherein R represents an alkylene group having one to five carbon atoms, a phenylene group or ##STR2## the pharmaceutically acceptable salts and esters thereof, and a pharmaceutically acceptable carrier therefor, and the method for treating nephritis.
    Type: Grant
    Filed: April 6, 1984
    Date of Patent: March 25, 1986
    Assignee: Kureha Kagaku Kogyo Kabushiki Kaisha
    Inventors: Hitoshi Takita, Sakuo Noda, Yutaka Mukaida, Hidetoshi Kobayashi
  • Patent number: 4464396
    Abstract: A novel compound of 4-[N-(hydroxybenzyl)aminomethyl]-cyclohexane-1-carboxylic acid represented by the general formula (I): ##STR1## wherein n is an integer of 1 to 3, or a salt or an ester thereof which has specific pharmacological activities, a method for preparing the derivative and a pharmacological composition in dosage unit form comprising the derivative as an active ingredient are disclosed herein.
    Type: Grant
    Filed: November 10, 1982
    Date of Patent: August 7, 1984
    Assignee: Kureha Kagaku Kogyo Kabushiki Kaisha
    Inventors: Hitoshi Takita, Yutaka Mukaida, Sakuo Noda, Hidetoshi Kobayashi
  • Patent number: 4409240
    Abstract: A novel derivative of dihydroxybenzoic acid represented by the formula (I) ##STR1## wherein R represents ##STR2## or a salt or an ester thereof which has specific pharmacological activities, a method for preparing thereof and a pharmaceutical composition comprising thereof as an active ingredient are provided.
    Type: Grant
    Filed: February 16, 1982
    Date of Patent: October 11, 1983
    Assignee: Kureha Kagaku Kogyo Kabushiki Kaisha
    Inventors: Hitoshi Takita, Yutaka Mukaida, Sakuo Noda, Hidetoshi Kobayashi
  • Patent number: 4387102
    Abstract: A novel compound of 4-[N-(3',4'-methylenedioxybenzylidene) aminomethyl]cyclohexane-1-carboxylic acid or a pharmaceutically acceptable salt or an C.sub.1 -C.sub.4 alkyl ester thereof which has specific pharmacologic activities, a method for preparing thereof and a pharmaceutical composition comprising thereof as an active ingredient are provided.
    Type: Grant
    Filed: December 17, 1981
    Date of Patent: June 7, 1983
    Assignee: Kureha Kagaku Kogyo Kabushiki Kaisha
    Inventors: Hitoshi Takita, Sakuo Noda, Yutaka Mukaida, Hidetoshi Kobayashi
  • Patent number: 4382955
    Abstract: A novel compound of 4-[N-(3',4'-dihydroxybenzylidene) aminomethyl]cyclohexane-1-carboxylic acid or a salt or an ester thereof which has specific pharmacologic activities, a method for preparing thereof and a pharmaceutical composition comprising thereof as an active ingredient are provided.
    Type: Grant
    Filed: May 26, 1981
    Date of Patent: May 10, 1983
    Assignee: Kureha Kagaku Kogyo Kabushiki Kaisha
    Inventors: Hitoshi Takita, Yutaka Mukaida, Sakuo Noda, Hidetoshi Kobayashi
  • Patent number: 4377594
    Abstract: A novel compound of 4-[N-(substituted-benzylidene)aminomethyl]cyclohexane-1-carboxylic acid or a salt or an ester thereof which has specific pharmacologic activities, a method for preparing thereof and a pharmaceutical composition comprising thereof as an active ingredient are provided.
    Type: Grant
    Filed: May 26, 1981
    Date of Patent: March 22, 1983
    Assignee: Kureha Kagaku Kogyo Kabushiki Kaisha
    Inventors: Hitoshi Takita, Yutaka Mukaida, Sakuo Noda, Hidetoshi Kobayashi
  • Patent number: 4369253
    Abstract: Disclosed is a method for producing the high-quality mycelia of the Basidiomycetes from culture thereof by promoting growth of the fungus as well as differentiation of the cells and attendant organization thereof by adding to the culture medium a straight chain saturated aliphatic alcohol with a catbon number within a specified range of 26 to 36 carbon atoms.
    Type: Grant
    Filed: March 24, 1981
    Date of Patent: January 18, 1983
    Assignee: Kureha Kagaku Kogyo Kabushiki Kaisha
    Inventors: Hitoshi Takita, Toshihiko Wada, Yutaka Mukaida, Satoru Enomoto, Akiyoshi Nakajima, Azuma Okubo
  • Patent number: 4294770
    Abstract: Disclosed herein is a process for preparing a normal long chain alkanoic acid having 26 to 36 carbon atoms, in which a trihalogenomethane is added to a normal alpha-olefin having 25 to 35 carbon atoms in the presence of a radical initiator and then the thus formed 1,1,1-trihalogenoalkane is hydrolyzed with an alkali to convert into the normal long chain alkanoic acid.
    Type: Grant
    Filed: February 15, 1980
    Date of Patent: October 13, 1981
    Assignee: Kureha Kagaku Kogyo Kabushiki Kaisha
    Inventors: Hitoshi Takita, Yutaka Mukaida, Satoru Enomoto
  • Patent number: 4277633
    Abstract: The palladium complex disclosed herein is bis[tri(ortho-tolyl)phosphine] :palladium which is produced by reacting a palladium salt with tri(ortho-tolyl)phosphine and reducing the resultant bis[tri(ortho-tolyl)phosphine] palladium salt with an alcoholic alkali. This complex is useful as a catalyst for the production of 1,3-diene oligomers.
    Type: Grant
    Filed: July 12, 1979
    Date of Patent: July 7, 1981
    Assignee: Kureha Kagaku Kogyo Kabushiki Kaisha
    Inventors: Satoru Enomoto, Hisayuki Wada, Sadao Nishita, Yutaka Mukaida, Mikiro Yanaka, Hitoshi Takita
  • Patent number: 4196135
    Abstract: The palladium complex disclosed herein is bis[tri(orthotolyl)phosphine] palladium which is produced by reacting a palladium salt with tri(ortho-tolyl)phosphine and reducing the resultant bis[tri(ortho-tolyl)phosphine] palladium salt with an alcoholic alkali. This complex is useful as a catalyst for the production of 1,3-diene oligomers.
    Type: Grant
    Filed: May 10, 1978
    Date of Patent: April 1, 1980
    Assignee: Kureha Kagaku Kogyo Kabushiki Kaisha
    Inventors: Satoru Enomoto, Hisayuki Wada, Sadao Nishita, Yutaka Mukaida, Mikiro Yanaka, Hitoshi Takita
  • Patent number: 4140663
    Abstract: An air drying high solid coating composition containing 90% or more of solid components and consisting of (1) 95 - 50 parts by weight of low viscosity alkyd resin having an oil length of 60 or higher and a viscosity of Z.sub.4 or lower, (II) 5 - 50 parts by weight of 1,1-bis-(1'-methyl-2'-vinyl-4',6'-heptadienoxy)-alkane, and if necessary, (III) other components such as pigments, organic solvents and additives. The coating composition is quite effective in the prevention of air pollution and the saving of resources.
    Type: Grant
    Filed: September 28, 1977
    Date of Patent: February 20, 1979
    Assignee: Kureha Chemical Industry Co., Ltd.
    Inventors: Satoru Enomoto, Yutaka Mukaida, Mikiro Yanaka, Sadao Nishita, Hisayuki Wada, Hitoshi Takita
  • Patent number: 4069211
    Abstract: A composition including a diisocyanate and 1-methyl-2-vinyl-4,6-heptadienol. This composition is capable of curing in air at room temperature after aging in a dry nitrogen atmosphere.
    Type: Grant
    Filed: June 28, 1976
    Date of Patent: January 17, 1978
    Assignee: Kureha Kagaku Kogyo Kabushiki Kaisha
    Inventors: Sadao Nishita, Satoru Enomoto, Hisayuki Wada, Yutaka Mukaida, Mikiro Yanaka, Hitoshi Takita
  • Patent number: 4028387
    Abstract: Reaction of (1-methyl-2-vinyl)4,6-heptadiene-1-ol with butadiene and carbon monoxide in the presence of a catalyst comprising palladium compounds and phosphine compounds provides a novel substance of (1-methyl-2-vinyl)4,6-heptadienyl-3,8-nonadienoate. This product can be made into a polymer at temperatures of 100.degree. to 250.degree. C.
    Type: Grant
    Filed: September 10, 1975
    Date of Patent: June 7, 1977
    Assignee: Kureha Kagaku Kogyo Kabushiki Kaisha
    Inventors: Satoru Enomoto, Hitoshi Takita, Hisayuki Wada, Yutaka Mukaida, Mikiro Yanaka
  • Patent number: 4025475
    Abstract: High solid type alkyd resin compositions comprising 90 to 10 percent by weight of alkyd resin and 10 to 90 percent by weight of (1-methyl-2-vinyl)4,6-heptadienyl-3,8-nonadienoate and compositions prepared, if necessary, by adding bodying agents, driers and/or a small amount of thinner.
    Type: Grant
    Filed: September 10, 1975
    Date of Patent: May 24, 1977
    Assignee: Kureha Kagaku Kogyo Kabushiki Kaisha
    Inventors: Satoru Enomoto, Hitoshi Takita, Hisayuki Wada, Yutaka Mukaida, Mikiro Yanaka
  • Patent number: 4021390
    Abstract: An alkyd resin composition including an alkyd resin and a 1,1-bis(1'-methyl-2'-vinyl-4',6'-heptadienoxy)alkane, useful as non-solvent type paint.
    Type: Grant
    Filed: June 17, 1976
    Date of Patent: May 3, 1977
    Assignee: Kureha Kagaku Kogyo Kabushiki Kaisha
    Inventors: Satoru Enomoto, Yutaka Mukaida, Mikiro Yanaka, Sadao Nishita, Hisayuki Wada, Hitoshi Takita