Patents by Inventor Yuxin Qian

Yuxin Qian has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Cefazolin sodium pentahydrate crystal and its molecular assembly preparation method
    Patent number: 8178521
    Abstract: The present invention relates to cefazolin sodium pentahydrate crystal and a method for assembly and preparation of the crystal molecule. The cefazolin sodium pentahydrate crystal molecule contains five water molecules, orthorhombic system, space group of C222(1), in which sodium ion is bonded to the cefazolin molecule with a coordinate bond. The method for assembly and preparation of cefazolin sodium pentahydrate crystal molecule are: adding a solvent to a reactor equipped with a jacket, adding cefazolin acid and a sodium salt, heating until the reaction solution is clear, stirring continuously, adjusting pH, upon the completion of the reaction, transferring the liquid into a jacketed crystallizer, adding crystal seeds or nucleating spontaneously, controlling cooling, slowly adding a antisolvent.
    Type: Grant
    Filed: September 15, 2006
    Date of Patent: May 15, 2012
    Assignees: Tianjin University, Shenzhen Gosun Pharmaceutical Co., Ltd.
    Inventors: Jingkang Wang, Yuxin Qian, Meijing Zhang, Jiehua Wu, Zhan'ao Yang
  • Cefazolin Sodium Pentahydrate Crystal and Its Molecular Assembly Preparation Method
    Publication number: 20090299056
    Abstract: The present invention relates to cefazolin sodium pentahydrate crystal and a method for assembly and preparation of the crystal molecule. The cefazolin sodium pentahydrate crystal molecule contains five water molecules, orthorhombic system, space group of C222(1), in which sodium ion is bonded to the cefazolin molecule with a coordinate bond. The method for assembly and preparation of cefazolin sodium pentahydrate crystal molecule are: adding a solvent to a reactor equipped with a jacket, adding cefazolin acid and a sodium salt, heating until the reaction solution is clear, stirring continuously, adjusting pH, upon the completion of the reaction, transferring the liquid into a jacketed crystallizer, adding crystal seeds or nucleating spontaneously, controlling cooling, slowly adding a antisolvent.
    Type: Application
    Filed: September 15, 2006
    Publication date: December 3, 2009
    Inventors: Jingkang Wang, Yuxin Qian, Meijing Zhang, Jiehua Wu, Zhan'ao Yang