Abstract: A landing gear includes structural parts arranged to connect a wheel to a structure of an aircraft, each structural part including two or more interfaces for connection to one or more other of the structural parts or to the structure of the aircraft and two or more webs which extend so as to face one another while delimiting between them a free space and which connect the two interfaces in order to transmit the forces from one to the other.

Abstract: An actuator includes a body and at least a first offset connection port that is connected to the body by a first duct projecting from the body. The first connection port is mechanically connected to the body at least by first and second struts. The first strut and the second strut extend from the first connection port, respectively, to a first segment of the body and to a second segment of the body that is axially spaced apart from the first segment. An undercarriage includes such an actuator as its locking or unlocking actuator.

Abstract: A landing gear includes structural parts arranged to connect a wheel to a structure of an aircraft, each structural part including two or more interfaces for connection to one or more other of the structural parts or to the structure of the aircraft and two or more webs which extend so as to face one another while delimiting between them a free space and which connect the two interfaces in order to transmit the forces from one to the other.

Abstract: A method of additive manufacturing including defining contiguous portions over a ceiling of a cavity of a part, including a central portion defined entirely by first edges, and peripheral portions defined by second edges and by a portion of a frontier of the ceiling. Defining a capital by facets that bear against the first edges and that converge towards an apex, and defining a slender support that extends from the capital to a cavity floor while being centered on the apex. For each peripheral portion, defining a capital by facets that bear against the second edges and that converge towards a terminal edge extending in a plane that is normal to a wall of the cavity, and defining a rib support that extends in the normal plane between the terminal edge and a wall of the cavity. Manufacturing the part including the cavity while making the supports and capitals.

Abstract: A ceiling of a cavity is provided with contiguous portions, including a central portion defined entirely by edges, and peripheral portions defined by edges and by a portion of a frontier of the ceiling. For the central portion, a capital is defined by facets that bear against the central portion edges and converge towards an apex, and a slender support column is centered on the apex and extends from the capital to a floor of the cavity. For each peripheral portion, a capital is defined by facets that bear against the peripheral portion edges and converge towards a terminal edge extending in a plane normal to a wall of the cavity, and a support rib extends in the normal plane between the terminal edge of the capital and a wall of the cavity. The method includes manufactured the part while making the above-defined supports and capitals by additive manufacturing.

Abstract: The invention relates to a system for the rotational decoupling of shafts, in particular drive shafts. The invention also relates to a generator protection system on a connection between a generator and a gas turbine engine. FIG. 1C illustrates the shaft-decoupling system in the decoupled position.

Abstract: Drive equipment for rotating by friction an aircraft wheel equipped with a drive track and mounted to turn about an axis (X) on an axle of an aircraft undercarriage. The equipment comprise a base (22), a slide (24) mounted on the base on a sliding axis extending in a radial direction (R1, R1), a support (26) pivotable on the slide on an axis parallel to the rotation axis of the wheel; two rollers (21) rotatable on rotation axes parallel to the pivot axis; a central shaft (28) mounted for rotation on the support and being in engagement with the two rollers to provide their rotation; and an actuator (23A, 23B, 30) for moving the slide and the support between a disengagement position with the rollers distant from the wheel drive track and an engagement position with the rollers are held in contact with the drive track of the wheel.

Abstract: The invention relates to a system for the rotational decoupling of shafts, in particular drive shafts. The invention also relates to a generator protection system on a connection between a generator and a gas turbine engine. FIG. 1C illustrates the shaft-decoupling system in the decoupled position.

Abstract: The present invention relates to the Transferrin (Tf) or an active fragment thereof for use in the treatment of retinal detachment and/or for use in the treatment of retinal detachment related to other diseases.

Abstract: Treatment of a disease associated with retinal degenerative disorder. The present invention relates to human Transferrin or an active fragment thereof for use in the treatment of a disease associated with retinal degenerative disorder.

Abstract: Drive equipment for rotating by friction an aircraft wheel equipped with a drive track and mounted to turn about an axis (X) on an axle of an aircraft undercarriage. The equipment comprise a base (22), a slide (24) mounted on the base on a sliding axis extending in a radial direction (R1, R1), a support (26) pivotable on the slide on an axis parallel to the rotation axis of the wheel; two rollers (21) rotatable on rotation axes parallel to the pivot axis; a central shaft (28) mounted for rotation on the support and being in engagement with the two rollers to provide their rotation; and an actuator (23A, 23B, 30) for moving the slide and the support between a disengagement position with the rollers distant from the wheel drive track and an engagement position with the rollers are held in contact with the drive track of the wheel.

Abstract: Treatment of a disease associated with retinal degenerative disorder. The present invention relates to human Transferrin or an active fragment thereof for use in the treatment of a disease associated with retinal degenerative disorder.

Abstract: The present invention provides a device and a method for the enhanced retinal delivery of nucleic acid therapeutics utilizing iontophoresis to evoke a transient elongation of the Müller Cells of a mammalian eye. The enhanced retinal deposition can be achieved by either a topical application, subconjunctival, or an intravitreal injection of the nucleic acid composition followed by, preceded by, or administered simultaneously with the iontophoretic application. The present invention thus provides a particularly advantageous method for the treatment of ocular diseases comprising the in vivo administration of a nucleic acid capable of alleviating the symptoms of a disease, the delivery of the nucleic acid being enhanced by using iontophoresis. This method can be applied particularly to the diseases of the retina resulting from an alteration of a gene expression and/or the over-expression of particular growth factors.

Abstract: The present invention provides a method for enhancing the in vivo delivery of chimeric oligonucleotides, containing for example DNA/2′OMeRNA, into cells of a plant, an animal or a human, comprising a step of applying topically to or injecting into a tissue, or tissue adjacent to a tissue, containing said cells, a composition comprising said chimeric oligonucleotide, followed by, preceded by, or simultaneously to a step of transferring said chimeric oligonucleotide into said cells by iontophoresis, and relates to a gene therapy method comprising the iontophorically transfer of a chimeric oligonucleotide DNA/2′OMeRNA. The present invention is also directed to particular chimeric oligonucleotides DNA/2′OMeRNA capable of inducing or inhibiting the expression of a specific gene involved in eye function by inducing or reverting a mutation in that specific gene, and their use as therapeutic composition for preventing or treating ocular diseases.

Abstract: A conjugate of a polypeptide reactive with a fibroblast growth factor receptor and a cytotoxic agent is used for inhibiting the proliferation of epithelial lens cells, especially following extracapsular cataract surgery.

Abstract: A conjugate of a polypeptide reactive with a fibroblast growth factor receptor and a cytotoxic agent is used for inhibiting the proliferation of epithelial lens cells, especially following extracapsular cataract surgery.

Abstract: A priority processor (1) and a non-priority processor (20) cooperatively access a common memory (30) by means of an address multiplexer (40) which memory and multiplexer are controlled by a control unit (60). The priority processor issues data strobe (DSSN), clock (CLK) and write control (WSN) signals to the control unit to which the non-polarity processor also issues various memory access request signals. By forming a preparation signal (DSSN=0), the priority processor, through the control unit, claims the memory for a memory access cycle if a prior memory access request by the non-priority processor occurred less than about a clock cycle earlier.

Abstract: A process for stimulating the growth of epidermis cells.The epidermis cells are contacted with an aqueous saline extract (RE) of ocular tissues. The process is especially applied for human epidermis cells.Application to the study of chromosomes of the human epidermis cell, particularly for the detection of natural or induced chromosome anomalies, and to the production of grafts, and especially autografts, usable on man, for example in the treatment of burns, cosmetic and diagnostic products.

Abstract: A process for stimulating the growth of human epidermal cells, applications of said process and products applying the said process.A process for stimulating the growth of epidermis cells.The epidermis cells are contacted with an aqueous saline extract (RE) of ocular tissues. The process is especially applied for human epidermis cells.Application to the study of chromosomes of the human epidermis cell, particularly for the detection of natural or induced chromosome anomalies, and to the production of grafts, and especially autografts, usable on man, for example in the treatment of burns, cosmetic and diagnostic products.

Abstract: A composition and a method for regenerating wounded or damaged corneal epelium are described. The composition comprises an aqueous solution containing an effective amount of ocular extract RE. The RE is extracted from eye tissues, such as choroid, iris and vitreous as well as aqueous humor. The active extract is obtained by the treatment of bovine ocular tissues with a buffered aqueous saline solution at pH of about 7.2. For ophthalmological use, the RE extract is purified by precipitation with acetic acid and dialyzed against physiologic saline NaCl solution. Such a composition is shown to increase significantly the rate of healing of wounded corneal epithelium.