Patents by Inventor Yves Larcher
Yves Larcher has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20220106546Abstract: The invention is an automated advanced tissue engineering system that comprises a housing in which one or more tissue engineering modules are accommodated together with a central microprocessor that controls functioning of the tissue engineering modules. In one embodiment, the tissue engineering module comprises a housing supporting one or more bioreactor chamber assemblies and a fluid reservoir operationally engageable with the housing. The bioreactor chamber assemblies may be selected depending on the end product option desired and may include, for example, a cell therapy bioreactor chamber, a single implant bioreactor chamber and a multiple (mosaic) implant bioreactor chamber.Type: ApplicationFiled: December 15, 2021Publication date: April 7, 2022Inventors: Timothy J.N. SMITH, Sydney M. PUGH, Lowell MISENER, Guy ORAM, Rupert HAGG, Roberto TOMMASINI, Yves LARCHER
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Publication number: 20220049199Abstract: The invention is an automated advanced tissue engineering system that comprises a housing in which one or more tissue engineering modules are accommodated together with a central microprocessor that controls functioning of the tissue engineering modules. In one embodiment, the tissue engineering module comprises a housing supporting one or more bioreactor chamber assemblies and a fluid reservoir operationally engageable with the housing. The bioreactor chamber assemblies may be selected depending on the end product option desired and may include, for example, a cell therapy bioreactor chamber, a single implant bioreactor chamber and a multiple (mosaic) implant bioreactor chamber.Type: ApplicationFiled: October 28, 2021Publication date: February 17, 2022Inventors: Timothy J.N. SMITH, Sydney M. PUGH, Lowell MISENER, Guy ORAM, Rupert HAGG, Roberto TOMMASINI, Yves LARCHER
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Publication number: 20210269755Abstract: The invention provides systems, modules, bioreactor and methods for the automated culture, proliferation, differentiation, production and maintenance of tissue engineered products. In one aspect is an automated tissue engineering system comprising a housing, at least one bioreactor supported by the housing, the bioreactor facilitating physiological cellular functions and/or the generation of one or more tissue constructs from cell and/or tissue sources. A fluid containment system is supported by the housing and is in fluid communication with the bioreactor. One or more sensors are associated with one or more of the housing, bioreactor or fluid containment system for monitoring parameters related to the physiological cellular functions and/or generation of tissue constructs; and a microprocessor linked to one or more of the sensors. The systems, methods and products of the invention find use in various clinical and laboratory settings.Type: ApplicationFiled: March 25, 2021Publication date: September 2, 2021Inventors: Timothy J.N. Smith, Sydney M. Pugh, Martin R. Pecaric, Rupert Hagg, Roberto Tommasini, Yves Larcher, Lowell D. Misener
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Publication number: 20210047597Abstract: The invention provides systems, modules, bioreactor and methods for the automated culture, proliferation, differentiation, production and maintenance of tissue engineered products. In one aspect is an automated tissue engineering system comprising a housing, at least one bioreactor supported by the housing, the bioreactor facilitating physiological cellular functions and/or the generation of one or more tissue constructs from cell and/or tissue sources. A fluid containment system is supported by the housing and is in fluid communication with the bioreactor. One or more sensors are associated with one or more of the housing, bioreactor or fluid containment system for monitoring parameters related to the physiological cellular functions and/or generation of tissue constructs; and a microprocessor linked to one or more of the sensors. The systems, methods and products of the invention find use in various clinical and laboratory settings.Type: ApplicationFiled: October 16, 2020Publication date: February 18, 2021Inventors: Timothy, J.N. SMITH, Sydney M. PUGH, Martin R. PECARIC, Rupert HAGG, Roberto TOMMASINI, Yves LARCHER, Lowell D. MISENER
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Publication number: 20210032583Abstract: The invention is an automated advanced tissue engineering system that comprises a housing in which one or more tissue engineering modules are accommodated together with a central microprocessor that controls functioning of the tissue engineering modules. In one embodiment, the tissue engineering module comprises a housing supporting one or more bioreactor chamber assemblies and a fluid reservoir operationally engageable with the housing. The bioreactor chamber assemblies may be selected depending on the end product option desired and may include, for example, a cell therapy bioreactor chamber, a single implant bioreactor chamber and a multiple (mosaic) implant bioreactor chamber.Type: ApplicationFiled: September 4, 2020Publication date: February 4, 2021Inventors: Timothy J.N. SMITH, Sydney M. PUGH, Lowell MISENER, Guy ORAM, Rupert HAGG, Roberto TOMMASINI, Yves LARCHER
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Patent number: 10844338Abstract: The invention provides systems, modules, bioreactor and methods for the automated culture, proliferation, differentiation, production and maintenance of tissue engineered products. In one aspect is an automated tissue engineering system comprising a housing, at least one bioreactor supported by the housing, the bioreactor facilitating physiological cellular functions and/or the generation of one or more tissue constructs from cell and/or tissue sources. A fluid containment system is supported by the housing and is in fluid communication with the bioreactor. One or more sensors are associated with one or more of the housing, bioreactor or fluid containment system for monitoring parameters related to the physiological cellular functions and/or generation of tissue constructs; and a microprocessor linked to one or more of the sensors. The systems, methods and products of the invention find use in various clinical and laboratory settings.Type: GrantFiled: July 14, 2020Date of Patent: November 24, 2020Assignee: OCTANE BIOTECH INC.Inventors: Timothy J. N. Smith, Sydney M. Pugh, Martin R. Pecaric, Rupert Hagg, Roberto Tommasini, Yves Larcher, Lowell D. Misener
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Publication number: 20200362288Abstract: The invention provides systems, modules, bioreactor and methods for the automated culture, proliferation, differentiation, production and maintenance of tissue engineered products. In one aspect is an automated tissue engineering system comprising a housing, at least one bioreactor supported by the housing, the bioreactor facilitating physiological cellular functions and/or the generation of one or more tissue constructs from cell and/or tissue sources. A fluid containment system is supported by the housing and is in fluid communication with the bioreactor. One or more sensors are associated with one or more of the housing, bioreactor or fluid containment system for monitoring parameters related to the physiological cellular functions and/or generation of tissue constructs; and a microprocessor linked to one or more of the sensors. The systems, methods and products of the invention find use in various clinical and laboratory settings.Type: ApplicationFiled: July 14, 2020Publication date: November 19, 2020Inventors: Timothy J.N. SMITH, Sydney M. PUGH, Martin R. PECARIC, Rupert HAGG, Roberto TOMMASINI, Yves LARCHER, Lowell D. MISENER
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Patent number: 10723986Abstract: The invention provides systems, modules, bioreactor and methods for the automated culture, proliferation, differentiation, production and maintenance of tissue engineered products. In one aspect is an automated tissue engineering system comprising a housing, at least one bioreactor supported by the housing, the bioreactor facilitating physiological cellular functions and/or the generation of one or more tissue constructs from cell and/or tissue sources. A fluid containment system is supported by the housing and is in fluid communication with the bioreactor. One or more sensors are associated with one or more of the housing, bioreactor or fluid containment system for monitoring parameters related to the physiological cellular functions and/or generation of tissue constructs; and a microprocessor linked to one or more of the sensors. The systems, methods and products of the invention find use in various clinical and laboratory settings.Type: GrantFiled: December 30, 2016Date of Patent: July 28, 2020Assignee: OCTANE BIOTECH INC.Inventors: Timothy J. N. Smith, Sydney M. Pugh, Martin R. Pecaric, Rupert Hagg, Roberto Tommasini, Yves Larcher, Lowell D. Misener
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Patent number: 9783768Abstract: The automated cell culture arrangement according to the invention comprises at least one closed cell culture module with at least one bioreactor. The closed cell culture module is a closed system, which means that within the closed cell culture module a closed sterile environment can be maintained. The automated cell culture arrangement according to the invention, further comprises at least one pump for pumping liquids within the closed cell culture module and at least one additional tool module, which is configured or configurable to act upon or to monitor the contents of a bioreactor and is movable relative to the at least one closed cell culture module or it is movable relative to one or several components of the at least one closed cell culture module.Type: GrantFiled: April 20, 2011Date of Patent: October 10, 2017Assignee: Octane Biotech, Inc.Inventors: Yves Larcher, Rupert Hagg
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Patent number: 9701932Abstract: The invention provides systems, modules, bioreactor and methods for the automated culture, proliferation, differentiation, production and maintenance of tissue engineered products. In one aspect is an automated tissue engineering system comprising a housing, at least one bioreactor supported by the housing, the bioreactor facilitating physiological cellular functions and/or the generation of one or more tissue constructs from cell and/or tissue sources. A fluid containment system is supported by the housing and is in fluid communication with the bioreactor. One or more sensors are associated with one or more of the housing, bioreactor or fluid containment system for monitoring parameters related to the physiological cellular functions and/or generation of tissue constructs; and a microprocessor linked to one or more of the sensors. The systems, methods and products of the invention find use in various clinical and laboratory settings.Type: GrantFiled: May 31, 2013Date of Patent: July 11, 2017Assignee: Octane Biotech Inc.Inventors: Timothy J. N. Smith, Sydney M. Pugh, Martin R. Pecaric, Rupert Hagg, Roberto Tommasini, Yves Larcher, Lowell D. Misener
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Publication number: 20170175063Abstract: The invention provides systems, modules, bioreactor and methods for the automated culture, proliferation, differentiation, production and maintenance of tissue engineered products. In one aspect is an automated tissue engineering system comprising a housing, at least one bioreactor supported by the housing, the bioreactor facilitating physiological cellular functions and/or the generation of one or more tissue constructs from cell and/or tissue sources. A fluid containment system is supported by the housing and is in fluid communication with the bioreactor. One or more sensors are associated with one or more of the housing, bioreactor or fluid containment system for monitoring parameters related to the physiological cellular functions and/or generation of tissue constructs; and a microprocessor linked to one or more of the sensors. The systems, methods and products of the invention find use in various clinical and laboratory settings.Type: ApplicationFiled: December 30, 2016Publication date: June 22, 2017Inventors: Timothy, J.N. Smith, Sydney M. Pugh, Martin R. Pecaric, Rupert Hagg, Roberto Tommasini, Yves Larcher, Lowell D. Misener
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Publication number: 20170096627Abstract: The invention is an automated advanced tissue engineering system that comprises a housing in which one or more tissue engineering modules are accomodated together with a central microprocessor that controls functioning of the tissue engineering modules. In one embodiment, the tissue engineering module comprises a housing supporting one or more bioreactor chamber assemblies and a fluid reservoir operationally engageable with the housing. The bioreactor chamber assemblies may be selected depending on the end product option desired and may include, for example, a cell therapy bioreactor chamber, a single implant bioreactor chamber and a multiple (mosaic) implant bioreactor chamber.Type: ApplicationFiled: October 14, 2016Publication date: April 6, 2017Inventors: Timothy J.N. Smith, Sydney M. Pugh, Lowell Misener, Guy Oram, Rupert Hagg, Roberto Tommasini, Yves Larcher
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Patent number: 9534195Abstract: The invention provides systems, modules, bioreactor and methods for the automated culture, proliferation, differentiation, production and maintenance of tissue engineered products. In one aspect is an automated tissue engineering system comprising a housing, at least one bioreactor supported by the housing, the bioreactor facilitating physiological cellular functions and/or the generation of one or more tissue constructs from cell and/or tissue sources. A fluid containment system is supported by the housing and is in fluid communication with the bioreactor. One or more sensors a associated with one or more of the housing, bioreactor or fluid containment system for monitoring parameters related to the physiological cellular functions and/or generation of tissue constructs; and a microprocessor linked to one or more of the sensors. The systems, methods and products of the invention find use in various clinical and laboratory settings.Type: GrantFiled: May 31, 2013Date of Patent: January 3, 2017Assignee: Octane Biotech Inc.Inventors: Timothy J. N. Smith, Sydney M. Pugh, Martin R. Pecaric, Rupert Hagg, Roberto Tommasini, Yves Larcher, Lowell D. Misener
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Patent number: 9499780Abstract: The invention is an automated advanced tissue engineering system that comprises a housing in which one or more tissue engineering modules are accommodated together with a central microprocessor that controls functioning of the tissue engineering modules. In one embodiment, the tissue engineering module comprises a housing supporting one or more bioreactor chamber assemblies and a fluid reservoir operationally engageable with the housing. The bioreactor chamber assemblies may be selected depending on the end product option desired and may include, for example, a cell therapy bioreactor chamber, a single implant bioreactor chamber and a multiple (mosaic) implant bioreactor chamber.Type: GrantFiled: May 26, 2005Date of Patent: November 22, 2016Assignee: OCTANE BIOTECH INC.Inventors: Timothy J. N. Smith, Sydney M. Pugh, Lowell Misener, Guy Oram, Rupert Hagg, Roberto Tommasini, Yves Larcher
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Publication number: 20140193895Abstract: The invention provides systems, modules, bioreactor and methods for the automated culture, proliferation, differentiation, production and maintenance of tissue engineered products. In one aspect is an automated tissue engineering system comprising a housing, at least one bioreactor supported by the housing, the bioreactor facilitating physiological cellular functions and/or the generation of one or more tissue constructs from cell and/or tissue sources. A fluid containment system is supported by the housing and is in fluid communication with the bioreactor. One or more sensors are associated with one or more of the housing, bioreactor or fluid containment system for monitoring parameters related to the physiological cellular functions and/or generation of tissue constructs; and a microprocessor linked to one or more of the sensors. The systems, methods and products of the invention find use in various clinical and laboratory settings.Type: ApplicationFiled: May 31, 2013Publication date: July 10, 2014Inventors: Timothy J.N. Smith, Sydney M. Pugh, Martin R. Pecaric, Rupert Hagg, Roberto Tommasini, Yves Larcher, Lowell D. Misener
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Publication number: 20140186937Abstract: The invention provides systems, modules, bioreactor and methods for the automated culture, proliferation, differentiation, production and maintenance of tissue engineered products. In one aspect is an automated tissue engineering system comprising a housing, at least one bioreactor supported by the housing, the bioreactor facilitating physiological cellular functions and/or the generation of one or more tissue constructs from cell and/or tissue sources. A fluid containment system is supported by the housing and is in fluid communication with the bioreactor. One or more sensors are associated with one or more of the housing, bioreactor or fluid containment system for monitoring parameters related to the physiological cellular functions and/or generation of tissue constructs; and a microprocessor linked to one or more of the sensors. The systems, methods and products of the invention find use in various clinical and laboratory settings.Type: ApplicationFiled: May 31, 2013Publication date: July 3, 2014Applicant: Octane Biotech Inc.Inventors: Timothy J.N. Smith, Sydney M. Pugh, Martin R. Pacaric, Rupert Hagg, Roberto Tommasini, Yves Larcher, Lowell D. Misener
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Publication number: 20130210130Abstract: The automated cell culture arrangement according to the invention comprises at least one closed cell culture module with at least one bioreactor. The closed cell culture module is a closed system, which means that within the closed cell culture module a closed sterile environment can be maintained. The automated cell culture arrangement according to the invention, further comprises at least one pump for pumping liquids within the closed cell culture module and at least one additional tool module, which is configured or configurable to act upon or to monitor the contents of a bioreactor and is movable relative to the at least one closed cell culture module or it is movable relative to one or several components of the at least one closed cell culture module.Type: ApplicationFiled: April 20, 2011Publication date: August 15, 2013Applicant: Octane Biotech, Inc.Inventors: Yves Larcher, Rupert Hagg
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Patent number: 8492140Abstract: The invention provides systems, modules, bioreactor and methods for the automated culture, proliferation, differentiation, production and maintenance of tissue engineered products. In one aspect is an automated tissue engineering system comprising a housing, at least one bioreactor supported by the housing, the bioreactor facilitating physiological cellular functions and/or the generation of one or more tissue constructs from cell and/or tissue sources. A fluid containment system is supported by the housing and is in fluid communication with the bioreactor. One or more sensors are associated with one or more of the housing, bioreactor or fluid containment system for monitoring parameters related to the physiological cellular functions and/or generation of tissue constructs; and a microprocessor linked to one or more of the sensors. The systems, methods and products of the invention find use in various clinical and laboratory settings.Type: GrantFiled: April 8, 2003Date of Patent: July 23, 2013Assignee: Octane Biotech Inc.Inventors: Timothy J. N. Smith, Martin R. Pecaric, Sydney J. Pugh, Rupert Hagg, Roberto Tommasini, Yves Larcher, Lowell D. Misner
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Publication number: 20080113426Abstract: The invention is an automated advanced tissue engineering system that comprises a housing in which one or more tissue engineering modules are accomodated together with a central microprocessor that controls functioning of the tissue engineering modules. In one embodiment, the tissue engineering module comprises a housing supporting one or more bioreactor chamber assemblies and a fluid reservoir operationally engageable with the housing. The bioreactor chamber assemblies may be selected depending on the end product option desired and may include, for example, a cell therapy bioreactor chamber, a single implant bioreactor chamber and a multiple (mosaic) implant bioreactor chamber.Type: ApplicationFiled: May 26, 2005Publication date: May 15, 2008Applicant: MILLENIUM BIOLOGIX INCInventors: Timothy J.N. Smith, Sydney M. Pugh, Lowell Misener, Guy Oram, Rupert Hagg, Roberto Tommasini, Yves Larcher