Patents by Inventor Yves Molino

Yves Molino has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Peptide derivatives and use thereof as carriers for molecules in the form of conjugates
    Patent number: 9328143
    Abstract: The invention relates to peptide derivatives (peptides and pseudo-peptides) and use thereof as vectors for molecules of interest. The invention also relates to conjugates containing a peptide derivative of the invention bound to a molecule of interest. The peptides and prodrug conjugates of the invention can be used to vectorize molecules of pharmaceutical or diagnostic interest, such as, for example, therapeutic molecules, imaging or diagnostic agents, or molecular probes, across cell membranes, and notably to promote their transport across the blood-brain barrier (BBB).
    Type: Grant
    Filed: May 14, 2014
    Date of Patent: May 3, 2016
    Assignees: VECT-HORUS, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE DE LA MEDITERRANEE (AIX MARSEILLE II)
    Inventors: Michel Khrestchatisky, Marion David, Yves Molino, Patrick Vlieghe
  • Peptide derivatives, preparation and uses thereof
    Patent number: 8877716
    Abstract: The invention relates to peptide derivatives (peptides and pseudo-peptides) and the use thereof as vectors for molecules of interest. The invention also relates to conjugates containing a peptide derivative of the invention bound to a molecule of interest. The peptides of the invention can be used, in particular, to vectorize, generally in the form of prodrug conjugates, molecules of pharmaceutical or diagnostic interest such as, for example, therapeutic molecules, imaging or diagnostic agents, or molecular probes, across cell membranes of different tissues or organs, healthy or pathologic, and in particular to enable their transport across physiological barriers of the nervous system such as the Blood brain barrier (BBB), Blood-spinal cord barrier (BSCB), or Blood-retinal barrier (BRB).
    Type: Grant
    Filed: October 19, 2012
    Date of Patent: November 4, 2014
    Assignees: Vect-Horus, Centre National de la Recherche Scientifique, Universite D'Aix-Marseille
    Inventors: Patrick Vlieghe, Marion David, Yves Molino, Michel Khrestchatisky
  • PEPTIDE DERIVATIVES AND USE THEREOF AS CARRIERS FOR MOLECULES IN THE FORM OF CONJUGATES
    Publication number: 20140243499
    Abstract: The invention relates to peptide derivatives (peptides and pseudo-peptides) and use thereof as vectors for molecules of interest. The invention also relates to conjugates containing a peptide derivative of the invention bound to a molecule of interest. The peptides and prodrug conjugates of the invention can be used to vectorise molecules of pharmaceutical or diagnostic interest, such as, for example, therapeutic molecules, imaging or diagnostic agents, or molecular probes, across cell membranes, and notably to promote their transport across the blood-brain barrier (BBB).
    Type: Application
    Filed: May 14, 2014
    Publication date: August 28, 2014
    Applicants: Vect-Horus, Centre National De La Recherche Scientifique, Universite D'Aix Marseille
    Inventors: MICHEL KHRESTCHATISKY, MARION DAVID, YVES MOLINO, PATRICK VLIEGHE
  • Peptide derivatives and use thereof as carriers for molecules in the form of conjugates
    Patent number: 8729029
    Abstract: The invention relates to peptide derivatives (peptides and pseudo-peptides) and use thereof as vectors for molecules of interest. The invention also relates to conjugates containing a peptide derivative of the invention bound to a molecule of interest. The peptides and prodrug conjugates of the invention can be used to vectorise molecules of pharmaceutical or diagnostic interest, such as, for example, therapeutic molecules, imaging or diagnostic agents, or molecular probes, across cell membranes, and notably to promote their transport across the blood-brain barrier (BBB).
    Type: Grant
    Filed: October 20, 2009
    Date of Patent: May 20, 2014
    Assignees: Vect-Horus, Centre National de la Recherche Scientifique, Universite d'Aix-Marseille
    Inventors: Michel Khrestchatisky, Marion David, Yves Molino, Patrick Vlieghe