Patents by Inventor Yvonne Pearl Bovell

Yvonne Pearl Bovell has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for in vitro production of bone
    Publication number: 20010032016
    Abstract: The invention relates to a method for an vitro production of bone tissue, comprising the steps of:
    Type: Application
    Filed: June 8, 2001
    Publication date: October 18, 2001
    Applicant: Iso Tis N.V.
    Inventors: Clemens Antoni Van Blitterswijk, Joost Dick De Bruijn, Yvonne Pearl Bovell
  • Method for in vitro production of bone
    Patent number: 6299650
    Abstract: The invention relates to a method for in vitro production of bone tissue, comprising the steps of: (a) applying undifferentiated mammalian cells, in particular autologous marrow cells, on a substrate; (b) directly contacting said cells with a culture medium for a sufficient time to produce a continuous matrix; (c) removing the substrate with the matrix from the culture medium. The produced matrix can be used for joint prostheses, maxillofacial implants, special surgery devices, or bone fillers. The contacted culture medium can also be used for the production of active factors such as growth factors.
    Type: Grant
    Filed: July 21, 2000
    Date of Patent: October 9, 2001
    Assignee: IsoTis N.V.
    Inventors: Clemens Antoni Van Blitterswijk, Joost Dick De Bruijn, Yvonne Pearl Bovell
  • Device for tissue engineering bone
    Patent number: 6228117
    Abstract: A device for bone tissue engineering is described which comprises a scaffold material consisting of a bioactive, osteoconductive and bone-bonding segmented thermoplastic copolyester and cultured osteogenic or osteoprogenitor cells, especially bone cells.
    Type: Grant
    Filed: July 15, 1998
    Date of Patent: May 8, 2001
    Assignee: IsoTis B.V.
    Inventors: Joost Dick De Bruijn, Yvonne Pearl Bovell, Jennigje Van Den Brink, Clemens Antoni Van Blitterswijk
  • Method for in vitro production of bone
    Patent number: 6152964
    Abstract: The invention relates to a method for in vitro production of bone tissue, comprising the steps of:(a) applying undifferentiated mammalian cells, in particular autologous marrow cells, on a substrate;(b) directly contacting said cells with a culture medium for a sufficient time to produce a continuous matrix;(c) removing the substrate with the matrix from the culture medium.The produced matrix can be used for joint prostheses, maxillofacial implants, special surgery devices, or bone fillers. The contacted culture medium can also be used for the production of active factors such as growth factors.
    Type: Grant
    Filed: March 3, 1997
    Date of Patent: November 28, 2000
    Assignee: IsoTis B.V.
    Inventors: Clemens Antoni Van Blitterswijk, Joost Dick De Bruijn, Yvonne Pearl Bovell