Patents by Inventor Zachary Garo Armen
Zachary Garo Armen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Patent number: 11974574Abstract: Provided herein are methods and compositions for modulating the fitness of a host invertebrate (e.g., insect, mollusk, or nematode) by altering interactions between the host and one or more micoorganisms resident in the host. The invention features a composition including a modulating agent (e.g., a polypeptide, nucleic acid, small molecule, or combinations thereof) that can induce changes in the host's microbiota in a manner that modulates (e.g., increases or decreases) host fitness. The modulating agent described herein may modulate the fitness of a variety of invertebrates that are important for agriculture, commerce, and/or public health.Type: GrantFiled: February 23, 2018Date of Patent: May 7, 2024Assignee: Flagship Pioneering Innovations V, Inc.Inventors: Ignacio Martinez, Zachary Garo Armen, Barry Andrew Martin, Maier Steve Avendano Amado
-
Patent number: 11690387Abstract: Provided herein are methods and compositions for food and feed applications, e.g., for targeting one or more microorganisms resident in a host insect, the modulation resulting in an increase in the fitness of the host. The invention features a composition that includes a modulating agent (e.g., phage, peptide, small molecule, antibiotic, or combinations thereof) that can alter the host's microbiota in a manner that is beneficial to the host. By promoting favorable microbial levels, microbial activity, microbial metabolism, and/or microbial diversity, the modulating agent described herein may be used to increase the fitness of a variety of insects utilized in human food or animal feed industries.Type: GrantFiled: January 24, 2018Date of Patent: July 4, 2023Assignee: Flagship Pioneering Innovations V, Inc.Inventors: Ignacio Martinez, Zachary Garo Armen, Christine Cezar, Barry Andrew Martin, Maier Steve Avendano Amado
-
Patent number: 11350648Abstract: Provided herein are agents, compositions, and methods for agricultural use, e.g., for altering the level, activity, or metabolism of one or more microorganisms resident in a host nematode or arthropod (e.g., honeybee or silkworm), the alteration resulting in an increase in the fitness of the host. The invention features a composition that includes an agent (e.g., phage, peptide, small molecule, antibiotic, or combinations thereof) that can alter the host's microbiota in a manner that is beneficial to the host. By promoting favorable microbial levels, microbial activity, microbial metabolism, and/or microbial diversity, the agents described herein may be used to increase the fitness of a variety of beneficial nematodes or arthropods, such as bees and silkworms, utilized in agriculture and commerce.Type: GrantFiled: January 24, 2018Date of Patent: June 7, 2022Assignee: Flagship Pioneering Innovations V, Inc.Inventors: Ignacio Martinez, Zachary Garo Armen, Jonathan Friedlander, Christine Cezar, Barry Andrew Martin, Maier Steve Avendano Amado
-
Publication number: 20210360934Abstract: Provided herein are agents, compositions, and methods useful for animal health, e.g., for altering the level, activity, or metabolism of one or more microorganisms resident in a host insect (e.g., arthropod, e.g., insect, e.g., pathogen vector), the alteration resulting in a decrease in the fitness of the host. The invention features a composition that includes an agent (e.g., phage, peptide, small molecule, antibiotic, or combinations thereof) that can alter the host's microbiota in a manner that is detrimental to the host. By disrupting microbial levels, microbial activity, microbial metabolism, or microbial diversity, the agents described herein may be used to decrease the fitness of a variety of insects that carry vector-borne pathogens that cause disease in animals.Type: ApplicationFiled: December 2, 2020Publication date: November 25, 2021Inventors: Ignacio MARTINEZ, Zachary Garo ARMEN, Barry Andrew MARTIN, Maier Steve AVENDANO AMADO
-
Publication number: 20210275635Abstract: Provided herein are methods and compositions useful for human health, e.g., for targeting one or more microorganisms resident in a host insect (e.g., arthropod, e.g., insect, e.g., pathogen vector), the modulation resulting in a decrease in the fitness of the host. The invention features a composition that includes a modulating agent (e.g., phage, peptide, small molecule, antibiotic, or combinations thereof) that can alter the host's microbiota in a manner that is detrimental to the host. By disrupting microbial levels, microbial activity, microbial metabolism, or microbial diversity, the modulating agent described herein may be used to decrease the fitness of a variety of insects that carry vector-home pathogens that cause disease in humans.Type: ApplicationFiled: December 14, 2020Publication date: September 9, 2021Inventors: Ignacio MARTINEZ, Zachary Garo ARMEN, Christine CEZAR, Barry Andrew MARTIN, Maier Steve AVENDANO AMADO
-
Publication number: 20210195917Abstract: Provided herein are agents, compositions, and methods for agricultural use, e.g., for altering the level, activity, or metabolism of one or more microorganisms resident in a host nematode or arthropod (e.g., honeybee or silkworm), the alteration resulting in an increase in the fitness of the host. The invention features a composition that includes an agent (e.g., phage, peptide, small molecule, antibiotic, or combinations thereof) that can alter the host's microbiota in a manner that is beneficial to the host. By promoting favorable microbial levels, microbial activity, microbial metabolism, and/or microbial diversity, the agents described herein may be used to increase the fitness of a variety of beneficial nematodes or arthropods, such as bees and silkworms, utilized in agriculture and commerce.Type: ApplicationFiled: July 27, 2020Publication date: July 1, 2021Inventors: Ignacio MARTINEZ, Zachary Garo ARMEN, Jonathan FRIEDLANDER, Christine CEZAR, Barry Andrew MARTIN, Maier Steve AVENDANO AMADO
-
Publication number: 20200261536Abstract: Provided herein are methods and compositions useful for human health, e.g., for targeting one or more microorganisms resident in a host insect (e.g., arthropod, e.g., insect, e.g., pathogen vector), the modulation resulting in a decrease in the fitness of the host. The invention features a composition that includes a modulating agent (e.g., phage, peptide, small molecule, antibiotic, or combinations thereof) that can alter the host's microbiota in a manner that is detrimental to the host. By disrupting microbial levels, microbial activity, microbial metabolism, or microbial diversity, the modulating agent described herein may be used to decrease the fitness of a variety of insects that carry vector-bore pathogens that cause disease in humans.Type: ApplicationFiled: March 23, 2020Publication date: August 20, 2020Inventors: Ignacio MARTINEZ, Zachary Garo ARMEN, Christine CEZAR, Barry Andrew MARTIN, Maier Steve AVENDANO AMADO
-
Publication number: 20200128856Abstract: Provided herein are methods and compositions for food and feed applications, e.g., for targeting one or more microorganisms resident in a host insect, the modulation resulting in an increase in the fitness of the host. The invention features a composition that includes a modulating agent (e.g., phage, peptide, small molecule, antibiotic, or combinations thereof) that can alter the host's microbiota in a manner that is beneficial to the host. By promoting favorable microbial levels, microbial activity, microbial metabolism, and/or microbial diversity, the modulating agent described herein may be used to increase the fitness of a variety of insects utilized in human food or animal feed industries.Type: ApplicationFiled: January 24, 2018Publication date: April 30, 2020Applicant: Flagship Pioneering Innovations V, Inc.Inventors: Ignacio MARTINEZ, Zachary Garo ARMEN, Christine CEZAR, Barry Andrew MARTIN, Maier Steve AVENDANO AMADO
-
Publication number: 20200129565Abstract: Provided herein are agents, compositions, and methods for agricultural use, e.g., for altering the level, activity, or metabolism of one or more microorganisms resident in a host nematode or arthropod (e.g., honeybee or silkworm), the alteration resulting in an increase in the fitness of the host. The invention features a composition that includes an agent (e.g., phage, peptide, small molecule, antibiotic, or combinations thereof) that can alter the host's microbiota in a manner that is beneficial to the host. By promoting favorable microbial levels, microbial activity, microbial metabolism, and/or microbial diversity, the agents described herein may be used to increase the fitness of a variety of beneficial nematodes or arthropods, such as bees and silkworms, utilized in agriculture and commerce.Type: ApplicationFiled: January 24, 2018Publication date: April 30, 2020Applicant: Flagship Pioneering Innovations V, Inc.Inventors: Ignacio MARTINEZ, Zachary Garo ARMEN, Jonathan FRIEDLANDER, Christine CEZAR, Barry Andrew MARTIN, Maier Steve AVENDANO AMADO
-
Publication number: 20200060286Abstract: Provided herein are agents, compositions, and methods useful for animal health, e.g., for altering the level, activity, or metabolism of one or more microorganisms resident in a host insect (e.g., arthropod, e.g., insect, e.g., pathogen vector), the alteration resulting in a decrease in the fitness of the host. The invention features a composition that includes an agent (e.g., phage, peptide, small molecule, antibiotic, or combinations thereof) that can alter the host's microbiota in a manner that is detrimental to the host. By disrupting microbial levels, microbial activity, microbial metabolism, or microbial diversity, the agents described herein may be used to decrease the fitness of a variety of insects that carry vector-borne pathogens that cause disease in animals.Type: ApplicationFiled: January 24, 2018Publication date: February 27, 2020Applicant: Flagship Pioneering Innovations V, Inc.Inventors: Ignacio MARTINEZ, Zachary Garo ARMEN, Barry Andrew MARTIN, Maier Steve AVENDANO AMADO
-
Publication number: 20190387748Abstract: Provided herein are agents, compositions, and methods for agricultural pest control, e.g., for altering the level, activity, or metabolism of one or more microorganisms resident in a host insect (e.g., agricultural pest), the alteration resulting in a decrease in the fitness of the host. The invention features a composition including an agent (e.g., phage, peptide, small molecule, antibiotic, or combinations thereof) that can alter the host's microbiota in a manner that is detrimental to the host. By disrupting microbial levels, microbial activity, microbial metabolism, and/or microbial diversity, the agents described herein may decrease the fitness of a variety of insects that are considered agricultural pests.Type: ApplicationFiled: January 24, 2018Publication date: December 26, 2019Inventors: Ignacio MARTINEZ, Zachary Garo ARMEN, Barry Andrew MARTIN, Maier Steve AVENDANO AMADO
-
Publication number: 20190365853Abstract: Provided herein are methods and compositions useful for human health, e.g., for targeting one or more microorganisms resident in a host insect (e.g., arthropod, e.g., insect, e.g., pathogen vector), the modulation resulting in a decrease in the fitness of the host. The invention features a composition that includes a modulating agent (e.g., phage, peptide, small molecule, antibiotic, or combinations thereof) that can alter the host's microbiota in a manner that is detrimental to the host. By disrupting microbial levels, microbial activity, microbial metabolism, or microbial diversity, the modulating agent described herein may be used to decrease the fitness of a variety of insects that carry vector-borne pathogens that cause disease in humans.Type: ApplicationFiled: January 24, 2018Publication date: December 5, 2019Inventors: Ignacio MARTINEZ, Zachary Garo ARMEN, Christine CEZAR, Barry Andrew MARTIN, Maier Steve AVENDANO AMADO
-
Publication number: 20190367943Abstract: Provided herein are methods and compositions for modulating the fitness of a host invertebrate (e.g., insect, mollusk, or nematode) by altering interactions between the host and one or more micoorganisms resident in the host. The invention features a composition including a modulating agent (e.g., a polypeptide, nucleic acid, small molecule, or combinations thereof) that can induce changes in the host's microbiota in a manner that modulates (e.g., increases or decreases) host fitness. The modulating agent described herein may modulate the fitness of a variety of invertebrates that are important for agriculture, commerce, and/or public health.Type: ApplicationFiled: February 23, 2018Publication date: December 5, 2019Applicant: Flagship Pioneering Innovations V, Inc.Inventors: Ignacio MARTINEZ, Zachary Garo ARMEN, Barry Andrew MARTIN, Maier Steve AVENDANO AMADO
-
Publication number: 20190246647Abstract: Provided herein are methods and compositions for modulating the fitness of a host invertebrate (e.g., insect, mollusk, or nematode) by altering interactions between the host and one or more micoorganisms resident in the host. The invention features a composition including a modulating agent (e.g., a polypeptide, nucleic acid, small molecule, or combinations thereof) that can induce changes in the host's microbiota in a manner that modulates (e.g., increases or decreases) host fitness. The modulating agent described herein may modulate the fitness of a variety of invertebrates that are important for agriculture, commerce, and/or public health.Type: ApplicationFiled: April 30, 2019Publication date: August 15, 2019Inventors: Ignacio MARTINEZ, Zachary Garo ARMEN, Barry Andrew MARTIN, Maier Steve AVENDANO AMADO
-
Publication number: 20190216093Abstract: Provided herein are agents, compositions, and methods for agricultural pest control, e.g., for altering the level, activity, or metabolism of one or more microorganisms resident in a host insect (e.g., agricultural pest), the alteration resulting in a decrease in the fitness of the host. The invention features a composition including an agent (e.g., phage, peptide, small molecule, antibiotic, or combinations thereof) that can alter the host's microbiota in a manner that is detrimental to the host. By disrupting microbial levels, microbial activity, microbial metabolism, and/or microbial diversity, the agents described herein may decrease the fitness of a variety of insects that are considered agricultural pests.Type: ApplicationFiled: April 2, 2019Publication date: July 18, 2019Inventors: Ignacio MARTINEZ, Zachary Garo ARMEN, Barry Andrew MARTIN, Maier Steve AVENDANO AMADO
-
Publication number: 20190191741Abstract: Provided herein are agents, compositions, and methods for agricultural use, e.g., for altering the level, activity, or metabolism of one or more microorganisms resident in a host nematode or arthropod (e.g., honeybee or silkworm), the alteration resulting in an increase in the fitness of the host. The invention features a composition that includes an agent (e.g., phage, peptide, small molecule, antibiotic, or combinations thereof) that can alter the host's microbiota in a manner that is beneficial to the host. By promoting favorable microbial levels, microbial activity, microbial metabolism, and/or microbial diversity, the agents described herein may be used to increase the fitness of a variety of beneficial nematodes or arthropods, such as bees and silkworms, utilized in agriculture and commerce.Type: ApplicationFiled: March 1, 2019Publication date: June 27, 2019Inventors: Ignacio Martinez, Zachary Garo Armen, Jonathan Friedlander, Christine Cezar, Barry Andrew Martin, Maier Steve Avendano Amado