Abstract: Polypeptides, such as antibody molecules and TCR molecules, and methods of making the same, are disclosed. The polypeptides can be used to treat, prevent, and/or diagnose disorders.

Abstract: Systems and methods of the present disclosure enable automated roof planning using a processor. The processor receives a digital image of a roof of a structure and models each roof plane of the roof to generate a roof model. The processor determines dimensions of each roof plane based on the roof model. The processor retrieves roofing accessory data from a database, the roofing accessory data solar roofing accessory part identifiers and solar roofing accessory part performance characteristics for solar roofing accessories. The processor simulates multiple candidate roof layouts based on the dimensions of each roof plan and the solar roofing accessory parts and determines a utilization prediction for each candidate layout. Based on each utilization prediction, the processor determines a particular roof layout having selected solar roofing accessory parts, and generates a solar roof design, including a list of materials, for the particular roof layout.

Abstract: Systems and methods of the present disclosure enable automated roof planning using a processor. The processor receives a digital image of a roof of a structure and models each roof plane of the roof to generate a roof model. The processor determines dimensions of each roof plane based on the roof model. The processor retrieves roofing accessory data from a database, the roofing accessory data solar roofing accessory part identifiers and solar roofing accessory part performance characteristics for solar roofing accessories. The processor simulates multiple candidate roof layouts based on the dimensions of each roof plan and the solar roofing accessory parts and determines a utilization prediction for each candidate layout. Based on each utilization prediction, the processor determines a particular roof layout having selected solar roofing accessory parts, and generates a solar roof design, including a list of materials, for the particular roof layout.

Abstract: In various examples, a technique for monitoring sensor performance is disclosed that includes aggregating sensor data collected by a sensor into a plurality of statistics for a plurality of sectors corresponding to a two-dimensional (2D) plane representing a sensory field of the sensor. The techniques also include determining a performance of the sensor based on the plurality of statistics and historical sensor data or information associated with the sensor. The techniques further include transmitting, to one or more components, one or more indications of the performance of the sensor to cause the one or more components to perform one or more operations in view of or accounting for the performance of the sensor.

Abstract: In various examples, an obstacle detector is capable of tracking a velocity state of detected objects or obstacles using LiDAR data. For example, using LiDAR data alone, an iterative closest point (ICP) algorithm may be used to determine a current state of detected objects for a current frame and a Kalman filter may be used to maintain a tracked state of the one or more objects detected over time. The obstacle detector may be configured to estimate velocity for one or more detected objects, compare the estimated velocity to one or more previous tracked states for previously detected objects, determine that the detected objects corresponds to a certain previously detected object, and update the tracked state for the previously detected object with the estimated velocity.

Abstract: The disclosure herein describes controlling focal parameters of a head mounted display based on an estimated user age to account for increasing likelihood of presbyopia as user age increases. The head mounted display uses eye tracking sensors to collect ocular metric data associated with ocular features of a user's eye and a user age estimate is calculated based on analysis of the ocular metric data using a machine learning algorithm and an ocular metric data set. Further, a confidence value of the user age estimate is calculated based on the analysis of the ocular metric data. Then, focal parameters of the visual display of the head mounted display are controlled based on the user age estimate and confidence value. The described focal control method provides a seamless, automated way for a head mounted display system to adjust settings to provide a sharp, in-focus user experience for users of all ages.

Abstract: The disclosure herein describes controlling focal parameters of a head mounted display based on an estimated user age to account for increasing likelihood of presbyopia as user age increases. The head mounted display uses eye tracking sensors to collect ocular metric data associated with ocular features of a user's eye and a user age estimate is calculated based on analysis of the ocular metric data using a machine learning algorithm and an ocular metric data set. Further, a confidence value of the user age estimate is calculated based on the analysis of the ocular metric data. Then, focal parameters of the visual display of the head mounted display are controlled based on the user age estimate and confidence value. The described focal control method provides a seamless, automated way for a head mounted display system to adjust settings to provide a sharp, in-focus user experience for users of all ages.

Abstract: A mechanism for limiting vibration amplitudes in a pumping system includes a plurality of pendulum absorbers coupled with a carrier and each having a pivoting range. The pendulum absorbers each further include a first and a second contact surface that contacts an outer peripheral surface of the carrier at limit stop positions, and each having a shape that is conforming with a shape of the outer peripheral surface. The pumping system may be used for pumping liquid nitrogen.

Abstract: A mechanism for limiting vibration amplitudes in a pumping system includes a plurality of pendulum absorbers coupled with a carrier and each having a pivoting range. The pendulum absorbers each further include a first and a second contact surface that contacts an outer peripheral surface of the carrier at limit stop positions, and each having a shape that is conforming with a shape of the outer peripheral surface. The pumping system may be used for pumping liquid nitrogen.

Abstract: The present invention relates to methods and reagents for use in site-selective modification of proteins having lysine residues with functionalized peptides using a chemoenzymatic microbial transglutaminase-mediated reaction. The functionalized proteins may be used for study or therapeutic uses.

Abstract: The present invention relates to methods and reagents for use in site-selective modification of proteins having lysine residues with functionalized peptides using a chemoenzymatic microbial transglutaminase-mediated reaction. The functionalized proteins may be used for study or therapeutic uses.

Abstract: The present invention relates to methods and reagents for use in site-selective modification of proteins having lysine residues with functionalized peptides using a chemoenzymatic microbial transglutaminase-mediated reaction. The functionalized proteins may be used for study or therapeutic uses.