Patents by Inventor Zandrie Hofman

Zandrie Hofman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9682119
    Abstract: This invention relates to a pea-based protein mixture and use thereof in a liquid nutritional composition, in particular suitable for tube feeding, and further relates to the liquid nutritional composition for providing long-term complete enteral nutrition to patients in need thereof. More specifically, the pea-based protein mixture and the liquid nutritional composition comprising the pea-based protein mixture comprises more than 25 weight % and up to 80 weight % of vegetable protein comprising a source of intact pea protein and a source of intact soy protein. The invention relates further to a method for long-term enteral nutrition of patients in need thereof comprising administering an effective amount of the liquid nutritional composition comprising the pea-based protein mixture, in particular comprising a defined amount of intact pea protein and a second vegetable intact protein, other than pea protein.
    Type: Grant
    Filed: May 22, 2015
    Date of Patent: June 20, 2017
    Assignee: N.V. Nutricia
    Inventors: Zandrie Hofman, Rogier Daniël Van Anholt, Wynette Hermina Agnes Kiers, Thomas Ludwig, Claudia Catharina Maria Van Den Braak, Marianne Klebach
  • Publication number: 20150250851
    Abstract: This invention relates to a pea-based protein mixture and use thereof in a liquid nutritional composition, in particular suitable for tube feeding, and further relates to said liquid nutritional composition for providing long-term complete enteral nutrition to patients in need thereof. More specifically, the pea-based protein mixture and the liquid nutritional composition comprising said pea-based protein mixture comprises more than 25 weight % and up to 80 weight % of vegetable protein comprising a source of intact pea protein and a source of intact soy protein. The invention relates further to a method for long-term enteral nutrition of patients in need thereof comprising administering an effective amount of said liquid nutritional composition comprising said pea-based protein mixture, in particular comprising a defined amount of intact pea protein and a second vegetable intact protein, other than pea protein.
    Type: Application
    Filed: May 22, 2015
    Publication date: September 10, 2015
    Applicant: N.V. Nutricia
    Inventors: Zandrie HOFMAN, Rogier Daniel VAN ANHOLT, Wynette Hermina Agnes KIERS, Thomas LUDWIG, Claudia Catharina Maria VAN DEN BRAAK, Marianne KLEBACH
  • Patent number: 9066537
    Abstract: This invention relates to a pea-based protein mixture and use thereof in a liquid nutritional composition, in particular suitable for tube feeding, and further relates to said liquid nutritional composition for providing long-term complete enteral nutrition to patients in need thereof. More specifically, the pea-based protein mixture and the liquid nutritional composition comprising said pea-based protein mixture comprises more than 25 weight % and up to 80 weight % of vegetable protein comprising a source of intact pea protein and a source of intact soy protein. The invention relates further to a method for long-term enteral nutrition of patients in need thereof comprising administering an effective amount of said liquid nutritional composition comprising said pea-based protein mixture, in particular comprising a defined amount of intact pea protein and a second vegetable intact protein, other than pea protein.
    Type: Grant
    Filed: April 27, 2010
    Date of Patent: June 30, 2015
    Assignee: N.V. Nutricia
    Inventors: Zandrie Hofman, Rogier Daniël Van Anholt, Wynette Hermina Agnes Kiers, Thomas Ludwig, Claudia Catharina Maria Van Den Braak, Marianne Klebach
  • Patent number: 9044043
    Abstract: This invention relates to a balanced fat composition and use thereof in a liquid nutritional composition, in particular suitable for tube feeding. This invention further relates to said liquid nutritional composition for providing enteral nutrition to patients in need thereof, in particular for providing a complete enteral nutrition, in particular for providing a long-term enteral nutrition. More specifically, the balanced fat composition and the liquid nutritional composition comprising said balanced fat composition comprises specific amounts of linoleic acid (LA), alpha-linolenic acid (ALA), docosahexaenoic acid (DHA), eicosapentaenoic acid (EPA), at least one medium chain fatty acid (MCFA), and at least one mono-unsaturated fatty acid (MUFA). The invention relates further to a method for providing enteral nutrition to patients in need thereof comprising administering an effective amount of said liquid nutritional composition comprising the balanced fat composition according to the invention.
    Type: Grant
    Filed: December 7, 2010
    Date of Patent: June 2, 2015
    Assignee: N.V. NUTRICIA
    Inventors: Rogier Daniël van Anholt, Zandrie Hofman, Wynette Hermina Agnes Kiers
  • Patent number: 8835383
    Abstract: This invention relates to the coagulation of protein containing nutritional compositions in the upper gastro-intestinal tract, more in particular in the stomach and provides a method for reducing suchcoagulation.
    Type: Grant
    Filed: April 27, 2010
    Date of Patent: September 16, 2014
    Assignee: N.V. Nutricia
    Inventors: Thomas Ludwig, Claudia Catharina Maria van den Braak, Marianne Klebach, Zandrie Hofman
  • Patent number: 8618047
    Abstract: The invention is directed to liquid enteral nutritional compositions comprising a protein fraction comprising more than 25 weight % and up to 80 weight % of a vegetable protein comprising at least a source of pea protein, and a fat fraction comprising (a) 8 to 15 weight % of linoleic acid; (b) 3.0 to 6.0 weight % of a combination of alpha-linolenic acid, docosahexaenoic acid and eicosapentaenoic acid, wherein the amount of ALA is >2.5 weight % and the combined amount of DHA and EPA is ?2.5 weight %; (c) 10 to 20 weight % of at least one medium-chain fatty acid; and (d) 35 to 79 weight % of at least one mono-unsaturated fatty acid. The compositions provide for a healthy and balanced diet, which is well-tolerated and minimises clinical complications that are frequently associated with the administration of enteral nutrition in patients using tube feeding, especially with respect to a reduced gastric emptying.
    Type: Grant
    Filed: July 27, 2012
    Date of Patent: December 31, 2013
    Assignee: N.V. Nutricia
    Inventors: Zandrie Hofman, Rogier Daniël van Anholt, Wynette Hermina Agnes Kiers, Marianne Klebach, Marloes Heleen van Beusekom
  • Publication number: 20130023468
    Abstract: The invention is directed to liquid enteral nutritional compositions comprising a protein fraction comprising more than 25 weight % and up to 80 weight % of a vegetable protein comprising at least a source of pea protein, and a fat fraction comprising (a) 8 to 15 weight % of linoleic acid; (b) 3.0 to 6.0 weight % of a combination of alpha-linolenic acid, docosahexaenoic acid and eicosapentaenoic acid, wherein the amount of ALA is >2.5 weight % and the combined amount of DHA and EPA is ?2.5 weight %; (c) 10 to 20 weight % of at least one medium-chain fatty acid; and (d) 35 to 79 weight % of at least one mono-unsaturated fatty acid. The compositions provide for a healthy and balanced diet, which is well-tolerated and minimises clinical complications that are frequently associated with the administration of enteral nutrition in patients using tube feeding, especially with respect to a reduced gastric emptying.
    Type: Application
    Filed: July 27, 2012
    Publication date: January 24, 2013
    Inventors: Zandrie HOFMAN, Rogier Daniël VAN ANHOLT, Wynette Hermina Agnes KIERS, Marianne KLEBACH, Marloes Helleen VAN BEUSEKOM
  • Publication number: 20120309831
    Abstract: This invention relates to a balanced fat composition and use thereof in a liquid nutritional composition, in particular suitable for tube feeding. This invention further relates to said liquid nutritional composition for providing enteral nutrition to patients in need thereof, in particular for providing a complete enteral nutrition, in particular for providing a long-term enteral nutrition. More specifically, the balanced fat composition and the liquid nutritional composition comprising said balanced fat composition comprises specific amounts of linoleic acid (LA), alpha-linolenic acid (ALA), docosahexaenoic acid (DHA), eicosapentaenoic acid (EPA), at least one medium chain fatty acid (MCFA), and at least one mono-unsaturated fatty acid (MUFA). The invention relates further to a method for providing enteral nutrition to patients in need thereof comprising administering an effective amount of said liquid nutritional composition comprising the balanced fat composition according to the invention.
    Type: Application
    Filed: December 7, 2010
    Publication date: December 6, 2012
    Applicant: N.V. NUTRICIA
    Inventors: Rogier Daniël Van Anholt, Zandrie Hofman, Wynette Hermina Agnes Kiers
  • Publication number: 20120283180
    Abstract: This invention relates to a pea-based protein mixture and use thereof in a liquid nutritional composition, in particular suitable for tube feeding, and further relates to said liquid nutritional composition for providing long-term complete enteral nutrition to patients in need thereof. More specifically, the pea-based protein mixture and the liquid nutritional composition comprising said pea-based protein mixture comprises more than 25 weight % and up to 80 weight % of vegetable protein comprising a source of intact pea protein and a source of intact soy protein. The invention relates further to a method for long-term enteral nutrition of patients in need thereof comprising administering an effective amount of said liquid nutritional composition comprising said pea-based protein mixture, in particular comprising a defined amount of intact pea protein and a second vegetable intact protein, other than pea protein.
    Type: Application
    Filed: April 27, 2010
    Publication date: November 8, 2012
    Applicant: N.V. NUTRICIA
    Inventors: Zandrie Hofman, Rogier Daniël Van Anholt, Wynette Hermina Agnes Kiers, Thomas Ludwig, Claudia Catharina Maria Van Den Braak, Marianne Klebach
  • Publication number: 20120094901
    Abstract: This invention relates to the coagulation of protein containing nutritional compositions in the upper gastro-intestinal tract, more in particular in the stomach and provides a method for reducing such coagulation.
    Type: Application
    Filed: April 27, 2010
    Publication date: April 19, 2012
    Inventors: Thomas Ludwig, Claudia Catharina Mari van den Braak, Marianne Klebach, Zandrie Hofman
  • Publication number: 20110034376
    Abstract: The invention pertains to the use of a lipid-rich nutrition for the manufacture of a composition for the prevention and/or treatment of post-operative ileus. The lipid fraction inhibited IL-6 and TNF-? levels in peritoneal lavage fluid, and/or wherein the lipid fraction prevents influx of neutrophils in the intestinal muscularis following intestinal manipulation. The nutritional composition comprises at least a lipid fraction which accounts for 42 to 90%, preferably between 45 and 70% of the total energy of the composition. The lipid fraction preferably contains 8 to 50 wt % of phospholipids.
    Type: Application
    Filed: August 6, 2010
    Publication date: February 10, 2011
    Applicant: N.V. Nutricia
    Inventors: Tim Lubbers, Houkje Bouritius, Misha D.P. Luyer, Willem Andries Buurman, Johannes Wilhelmus Maria Greve, Zandrie Hofman
  • Publication number: 20070190064
    Abstract: Enteral compositions and use thereof, which compositions contain proteins and lipids, for the prevention and/or treatment of sepsis; the lipid fraction being particularly rich in phospholipids.
    Type: Application
    Filed: February 5, 2005
    Publication date: August 16, 2007
    Applicant: N.V. NUTRICIA
    Inventors: Gelske Speelmans, Adrianus Vriesema, Anita Vreugdenhil, Willem Buurman, Johannes Greve, Zandrie Hofman, Inge Kivit, Robert Hageman
  • Publication number: 20060270615
    Abstract: A preparation contains a) at least one substance having xanthine oxidase inhibiting properties; b) at least one substance having superoxide radical scavenging properties; c) at least one substance having peroxyl radical scavenging properties; These preparations are particularly suitable for treating damage caused by ischemia/reperfusion and oxidative stress, preventing multiple organ failure, treating subfertility and treating or preventing peri-operative complications
    Type: Application
    Filed: August 9, 2006
    Publication date: November 30, 2006
    Applicant: N.V. NUTRICIA
    Inventors: Klaske Van Norren, Eduard Van Hoorn, Hendrik Leuvenink, Zandrie Hofman
  • Publication number: 20040076692
    Abstract: The present invention relates to a preparation containing a) at least one substance having xanthine oxidase inhibiting properties; b) at least one substance having superoxide radical scavenging properties; c) at least one substance having peroxyl radical scavenging properties. These preparations are particularly suitable for treating damage casued by ischemia/reperfusion and oxidative stress, preventing multiple organ failure, treating subfertility and treating or preventing peri-operative complications.
    Type: Application
    Filed: January 15, 2003
    Publication date: April 22, 2004
    Inventors: Klaske Van Norren, Eduard Christiaan Van Hoorn, Hendrik Gerrit Derk Leuvenink, Zandrie Hofman