Patents by Inventor Zarghun Nazir

Zarghun Nazir has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods of producing molindone and its salts
    Patent number: 11117862
    Abstract: The present invention is directed towards novel methods of synthesis of molindone, synthesis of the intermediates of molindone, and high-purity compositions of molindone. In particular, the invention relates to the methods of synthesis of molindone through the Mannich reaction.
    Type: Grant
    Filed: April 30, 2020
    Date of Patent: September 14, 2021
    Assignee: Supernus Pharmaceuticals, Inc.
    Inventors: Martin Hanbauer, Zarghun Nazir, Peter Hildebrand, Attilia Figini, Likan Liang, Tiziano Fumagalli
  • METHODS OF PRODUCING MOLINDONE AND ITS SALTS
    Publication number: 20200262789
    Abstract: The present invention is directed towards novel methods of synthesis of molindone, synthesis of the intermediates of molindone, and high-purity compositions of molindone. In particular, the invention relates to the methods of synthesis of molindone through the Mannich reaction.
    Type: Application
    Filed: April 30, 2020
    Publication date: August 20, 2020
    Applicant: Supernus Pharmaceuticals, Inc.
    Inventors: Martin Hanbauer, Zarghun Nazir, Peter Hildebrand, Attilia Figini, Likan Liang, Tiziano Fumagalli
  • Methods of producing molindone and its salts
    Patent number: 10676432
    Abstract: The present invention is directed towards novel methods of synthesis of molindone, synthesis of the intermediates of molindone, and high-purity compositions of molindone. In particular, the invention relates to the methods of synthesis of molindone through the Mannich reaction.
    Type: Grant
    Filed: August 21, 2018
    Date of Patent: June 9, 2020
    Assignee: Supernus Pharmaceuticals, Inc.
    Inventors: Martin Hanbauer, Zarghun Nazir, Peter Hildebrand, Attilia Figini, Likan Liang, Tiziano Fumagalli
  • METHODS OF PRODUCING MOLINDONE AND ITS SALTS
    Publication number: 20190218179
    Abstract: The present invention is directed towards novel methods of synthesis of molindone, synthesis of the intermediates of molindone, and high-purity compositions of molindone. In particular, the invention relates to the methods of synthesis of molindone through the Mannich reaction.
    Type: Application
    Filed: August 21, 2018
    Publication date: July 18, 2019
    Applicant: Supernus Pharmaceuticals, Inc.
    Inventors: Martin HANBAUER, Zarghun NAZIR, Peter HILDEBRAND, Attilia FIGINI, Likan LIANG, Tiziano FUMAGALLI
  • Methods of producing molindone and its salts
    Patent number: 10081595
    Abstract: The present invention is directed towards novel methods of synthesis of molindone, synthesis of the intermediates of molindone, and high-purity compositions of molindone. In particular, the invention relates to the methods of synthesis of molindone through the Mannich reaction.
    Type: Grant
    Filed: October 3, 2017
    Date of Patent: September 25, 2018
    Assignee: Supernus Pharmaceuticals, Inc.
    Inventors: Martin Hanbauer, Zarghun Nazir, Peter Hildebrand, Attilia Figini, Likan Liang, Tiziano Fumagalli
  • METHODS OF PRODUCING MOLINDONE AND ITS SALTS
    Publication number: 20180029982
    Abstract: The present invention is directed towards novel methods of synthesis of molindone, synthesis of the intermediates of molindone, and high-purity compositions of molindone. In particular, the invention relates to the methods of synthesis of molindone through the Mannich reaction.
    Type: Application
    Filed: October 3, 2017
    Publication date: February 1, 2018
    Applicant: Supernus Pharmaceuticals, Inc.
    Inventors: Martin HANBAUER, Zarghun NAZIR, Peter HILDEBRAND, Attilia FIGINI, Likan LIANG, Tiziano FUMAGALLI
  • Methods of producing molindone and its salts
    Patent number: 9802893
    Abstract: The present invention is directed towards novel methods of synthesis of molindone, synthesis of the intermediates of molindone, and high-purity compositions of molindone. In particular, the invention relates to the methods of synthesis of molindone through the Mannich reaction.
    Type: Grant
    Filed: November 30, 2016
    Date of Patent: October 31, 2017
    Assignee: Supernus Pharmaceuticals, Inc.
    Inventors: Martin Hanbauer, Zarghun Nazir, Peter Hildebrand, Attilia Figini, Likan Liang, Tiziano Fumagalli
  • METHODS OF PRODUCING MOLINDONE AND ITS SALTS
    Publication number: 20170101377
    Abstract: The present invention is directed towards novel methods of synthesis of molindone, synthesis of the intermediates of molindone, and high-purity compositions of molindone. In particular, the invention relates to the methods of synthesis of molindone through the Mannich reaction.
    Type: Application
    Filed: November 30, 2016
    Publication date: April 13, 2017
    Applicant: Supernus Pharmaceuticals, Inc.
    Inventors: Martin HANBAUER, Zarghun NAZIR, Peter HILDEBRAND, Attilia FIGINI, Likan LIANG, Tiziano FUMAGALLI
  • Methods of producing molindone and its salts
    Patent number: 9562011
    Abstract: The present invention is directed towards novel methods of synthesis of molindone, synthesis of the intermediates of molindone, and high-purity compositions of molindone. In particular, the invention relates to the methods of synthesis of molindone through the Mannich reaction.
    Type: Grant
    Filed: January 29, 2015
    Date of Patent: February 7, 2017
    Assignee: Supernus Pharmaceuticals, Inc.
    Inventors: Martin Hanbauer, Zarghun Nazir, Peter Hildebrand, Attilia Figini, Likan Liang, Tiziano Fumagalli
  • METHODS OF PRODUCING MOLINDONE AND ITS SALTS
    Publication number: 20150141645
    Abstract: The present invention is directed towards novel methods of synthesis of molindone, synthesis of the intermediates of molindone, and high-purity compositions of molindone. In particular, the invention relates to the methods of synthesis of molindone through the Mannich reaction.
    Type: Application
    Filed: January 29, 2015
    Publication date: May 21, 2015
    Inventors: Martin HANBAUER, Zarghun NAZIR, Peter HILDEBRAND, Attilia FIGINI, Likan LIANG, Tiziano FUMAGALLI
  • Methods of producing molindone and its salts
    Patent number: 8957206
    Abstract: The present invention is directed towards novel methods of synthesis of molindone, synthesis of the intermediates of molindone, and high-purity compositions of molindone. In particular, the invention relates to the methods of synthesis of molindone through the Mannich reaction.
    Type: Grant
    Filed: March 15, 2013
    Date of Patent: February 17, 2015
    Assignee: Supernus Pharmaceuticals Inc.
    Inventors: Martin Hanbauer, Zarghun Nazir, Peter Hildebrand, Attilia Figini, Likan Liang, Tiziano Fumagalli
  • METHODS OF PRODUCING MOLINDONE AND ITS SALTS
    Publication number: 20140081020
    Abstract: The present invention is directed towards novel methods of synthesis of molindone, synthesis of the intermediates of molindone, and high-purity compositions of molindone. In particular, the invention relates to the methods of synthesis of molindone through the Mannich reaction.
    Type: Application
    Filed: March 15, 2013
    Publication date: March 20, 2014
    Inventors: Martin Hanbauer, Zarghun Nazir, Peter Hildebrand, Attilia Figini, Likan Liang, Tiziano Fumagalli
  • Process for the preparation of an enantiomeric trisubstituted 3,4-dihydro-isoquinoline derivative
    Patent number: 8314238
    Abstract: The present invention relates to a process for the preparation of the compound of formula (7) which process comprises the hydrogenation of the compound of formula (4) using bis[chloro-1,5-cyclooctadiene-iridium], (S)-i-dicyclohexylphosphino-2-[(S)-?-(dimethylamino)-2-(dicyclohexylphosphino)benzyl]-ferrocene as a catalyst.
    Type: Grant
    Filed: December 23, 2008
    Date of Patent: November 20, 2012
    Assignee: Actelion Pharmaceuticals Ltd.
    Inventors: Erhard Bappert, Andreas Hendrikus Maria De Vries, Doris Domin, Matthias Helms, Christoph Imboden, Zarghun Nazir, Wolfgang Skranc, Felix Spindler, Michael Stanek, Wilhelm Tschebull, Gerardus Karel Maria Verzijl
  • Trisubstituted 3,4-dihydro-1H-isoquinolin compound, process for its preparation, and its use
    Patent number: 8247560
    Abstract: The present invention relates to the compound of formula 7*acetate (see below), a process for its preparation, and its use
    Type: Grant
    Filed: July 2, 2009
    Date of Patent: August 21, 2012
    Assignee: Actelion Pharmaceuticals Ltd.
    Inventors: Maria Andreas Hendrikus De Vries, Doris Domin, Matthias Helms, Christoph Imboden, Ralph Koberstein, Zarghun Nazir, Wolfgang Skranc, Michael Stanek, Wilhelm Tschebull, Maria Gerardus Karel Verzijl, Jurgen Stichler
  • PROCESS FOR THE PREPARATION OF AN ENANTIOMERIC TRISUBSTITUTED 3,4-DIHYDRO-ISOQUINOLINE DERIVATIVE
    Publication number: 20100305325
    Abstract: The present invention relates to a process for the preparation of the compound of formula (7) which process comprises the hydrogenation of the compound of formula (4) using bis[chloro-1,5-cyclooctadiene-iridium], (S)-i-dicyclohexylphosphino-2-[(S)-?-(dimethylamino)-2-(dicyclohexylphosphino)benzyl]-ferrocene as a catalyst.
    Type: Application
    Filed: December 23, 2008
    Publication date: December 2, 2010
    Inventors: Erhard Bappert, Andreas Hendrikus Maria De Vries, Doris Domin, Matthias Helms, Christoph Imboden, Zarghun Nazir, Wolfgang Skranc, Felix Spindler, Michael Stanek, Wilhelm Tschebull, Gerardus Karel Maria Verzijl
  • TRISUBSTITUTED 3,4-DIHYDRO-1H-ISOQUINOLIN COMPOUND, PROCESS FOR ITS PREPARATION, AND ITS USE
    Publication number: 20100010226
    Abstract: The present invention relates to the compound of formula 7*acetate (see below), a process for its preparation, and its use
    Type: Application
    Filed: July 2, 2009
    Publication date: January 14, 2010
    Inventors: Maria Andreas Hendrikus De Vries, Doris Domin, Matthias Helms, Chistoph Imboden, Ralph Koberstein, Zarghun Nazir, Wolfgang Skranc, Michael Stanek, Wilhelm Tschebull, Maria Gerardus Karel Verzijl, Jürgen Stichler