Patents by Inventor Zdena Kozlova

Zdena Kozlova has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Hydrogel-based prosthetic device for replacing at least a part of the nucleus of a spinal disc
    Patent number: 7204897
    Abstract: The present invention is a prosthetic for replacement of at least a part of the nucleus of a intravertebral disc. The prosthetic device is composed of at least two essentially parallel soft layers of an elastically deformable hydrogel and at least one rigid layer, the rigid layer having less compressibility than the soft layers, being adjacent to the soft layers, parallel to them, and firmly attached to them. In some embodiments, the soft layers have the same thickness and composition. Typically, the prosthesis has more than one rigid layer and these rigid layers have the same thickness and composition. The number of soft layers is usually one more than the number of rigid layers, with, e.g., at least three soft layers.
    Type: Grant
    Filed: April 23, 2004
    Date of Patent: April 17, 2007
    Assignee: Replication Medical, Inc.
    Inventors: Vladimir A. Stoy, Petr Stehlicek, Zdena Kozlova, Tomas Drunecky
  • Hydrogel-based prosthetic device for replacing at least a part of the nucleus of a spinal disc
    Publication number: 20050171611
    Abstract: The present invention is a prosthetic for replacement of at least a part of the nucleus of a intravertebral disc. The prosthetic device is composed of at least two essentially parallel soft layers of an elastically deformable hydrogel and at least one rigid layer, the rigid layer having less compressibility than the soft layers, being adjacent to the soft layers, parallel to them, and firmly attached to them. In some embodiments, the soft layers have the same thickness and composition. Typically, the prosthesis has more than one rigid layer and these rigid layers have the same thickness and composition. The number of soft layers is usually one more than the number of rigid layers, with, e.g., at least three soft layers.
    Type: Application
    Filed: April 23, 2004
    Publication date: August 4, 2005
    Inventors: Vladimir Stoy, Petr Stehlicek, Zdena Kozlova, Tomas Drunecky
  • Hydrogel-based prosthetic device for replaceing at least a part of the nucleus of a spinal disc
    Patent number: 6726721
    Abstract: The present invention is a prosthetic for replacement of at least a part of the nucleus of a intravertebral disc. The prosthetic device is composed of at least two essentially parallel soft layers of an elastically deformable hydrogel and at least one rigid layer, the rigid layer having less compressibility than the soft layers, being adjacent to the soft layers, parallel to them, and firmly attached to them. In some embodiments, the soft layers have the same thickness and composition. Typically, the prosthesis has more than one rigid layer and these rigid layers have the same thickness and composition. The number of soft layers is usually one more than the number of rigid layers, with, e.g., at least three soft layers.
    Type: Grant
    Filed: May 10, 2001
    Date of Patent: April 27, 2004
    Assignee: Replication Medical Inc.
    Inventors: Vladimir A. Stoy, Petr Stehlicek, Zdena Kozlova, Tomas Drunecky
  • Method of making synthetic hydrophilic polymers and products resulting therefrom
    Patent number: 6617390
    Abstract: The present invention involves a method of making a multiblock copolymer containing two or more types of sequences of derivatives of acrylic acid with at least one derivative being acrylic acid salt and at least one being acrylamide. The method includes: (e) in sequence, a first step being a catalytic reaction of nitrile groups in polyacrylonitrile dissolved in an inorganic aqueous solvent of polyacrylonitrile; and, (f) at least one subsequent step being at least one catalytic reaction of nitrile groups in absence of polyacrylonitrile solvents. The present invention also pertains to the products resulting from the method.
    Type: Grant
    Filed: July 11, 2002
    Date of Patent: September 9, 2003
    Assignee: Replication Medical, Inc.
    Inventors: Vladimer A. Stoy, Petr Stehlicek, Zdena Kozlova, Tomas Drunecky
  • Hydrogel-based prosthetic device for replaceing at least a part of the nucleus of a spinal disc
    Publication number: 20030055506
    Abstract: The present invention is a prosthetic for replacement of at least a part of the nucleus of a intravertebral disc. The prosthetic device is composed of at least two essentially parallel soft layers of an elastically deformable hydrogel and at least one rigid layer, the rigid layer having less compressibility than the soft layers, being adjacent to the soft layers, parallel to them, and firmly attached to them. In some embodiments, the soft layers have the same thickness and composition. Typically, the prosthesis has more than one rigid layer and these rigid layers have the same thickness and composition. The number of soft layers is usually one more than the number of rigid layers, with, e.g., at least three soft layers.
    Type: Application
    Filed: May 10, 2001
    Publication date: March 20, 2003
    Inventors: Vladimir A. Stoy, Petr Stehlicek, Zdena Kozlova, Tomas Drunecky
  • Method of making synthetic hydrophilic polymers and products resulting therefrom
    Publication number: 20020193531
    Abstract: The present invention involves a method of making a multiblock copolymer containing two or more types of sequences of derivatives of acrylic acid with at least one derivative being acrylic acid salt and at least one being acrylamide.
    Type: Application
    Filed: July 11, 2002
    Publication date: December 19, 2002
    Applicant: REPLICATION MEDICAL, INC.
    Inventors: Vladimir A. Stoy, Petr Stehlicek, Zdena Kozlova, Tomas Drunecky
  • Method of making synthetic hydrophilic polymers and products resulting therefrom
    Patent number: 6451922
    Abstract: The present invention involves a method of making a multiblock copolymer containing two or more types of sequences of derivatives of acrylic acid with at least one derivative being acrylic acid salt and at least one being acrylamide. The method includes: (e) in sequence, a first step being a catalytic reaction of nitrile groups in polyacrylonitrile dissolved in an inorganic aqueous solvent of polyacrylonitrile; and, (f) at least one subsequent step being at least one catalytic reaction of nitrile groups in absence of polyacrylonitrile solvents.The present invention also pertains to the products resulting from the method.
    Type: Grant
    Filed: April 19, 2001
    Date of Patent: September 17, 2002
    Assignee: Replication Medical, Inc.
    Inventors: Vladimer A. Stoy, Petr Stehlicek, Zdena Kozlova, Tomas Drunecky
  • Method of making synthetic hydrophilic polymers and products resulting therefrom
    Publication number: 20010044502
    Abstract: The present invention involves a method of making a multiblock copolymer containing two or more types of sequences of derivatives of acrylic acid with at least one derivative being acrylic acid salt and at least one being acrylamide.
    Type: Application
    Filed: April 19, 2001
    Publication date: November 22, 2001
    Applicant: Replication Medical, Inc.
    Inventors: Vladimir A. Stoy, Petr Stehlicek, Zdena Kozlova, Tomas Drunecky