Abstract: An oligopeptide with lipid-lowering activity, a preparation method and an application thereof are provided, belonging to the field of biotechnology. The amino acid sequence of the oligopeptide with lipid-lowering activity is shown in SEQ ID NO: 1. The preparation method includes the following steps: (1) hydrolyzing a loach protein with proteases to obtain an enzymatic hydrolysis product; (2) separating the enzymatic hydrolysis product using an ultrafiltration membrane, and taking a component with a molecular weight less than 3 kilodalton (kDa); and (3) filtering and separating the component with the molecular weight less than 3 kDa by Sephadex G-15 to obtain the oligopeptide. The oligopeptide is derived from the loach protein and has the characteristics of high safety, high efficiency, and wide sources.

Abstract: The present disclosure relates to combination therapies containing one or more PARP inhibitors and one or more angiogenesis inhibitor. Also described herein are therapeutic uses of such combination therapies for treating various disorders and conditions. The combination therapies and uses thereof can be useful for preventing tumor cell growth, preventing tumor metastasis, inducing an immune response or enhancing an immune response.

Abstract: The present invention provides methods of treatment for cancer through combination therapy with an agent that inhibits programmed death-1 protein (PD-1) signaling and an agent that inhibits poly[ADP-ribose] polymerase (PARP) signaling.

Abstract: The present invention provides methods of treatment for cancer(s) through combination therapy with an agent that inhibits poly [ADP-ribose] polymerase (PARP) signaling and an agent that regulates activity within the tumor microenvironment.

Abstract: The present invention provides methods of treatment for cancer(s) through combination therapy with an agent that inhibits poly [ADP-ribose] polymerase (PARP) signaling and an agent that regulates activity within the tumor microenvironment.

Abstract: The present disclosure relates to combination therapies containing one or more PARP inhibitors and one or more angiogenesis inhibitor. Also described herein are therapeutic uses of such combination therapies for treating various disorders and conditions. The combination therapies and uses thereof can be useful for preventing tumor cell growth, preventing tumor metastasis, inducing an immune response or enhancing an immune response.

Abstract: The present invention provides methods of treatment for cancer through combination therapy with an agent that inhibits programmed death-1 protein (PD-1) signaling and an agent that inhibits poly [ADP-ribose] polymerase (PARP) signaling.

Abstract: A self-calibrating transceiver includes a baseband processor, a receiver chain comprising an amplifier and a digital front end (DFE), and a transmitter chain, and a calibration control state machine. The state machine stores amplifier gain steps and is in communication with the transmitter chain, the receiver chain, and the baseband processor. The state machine can set a receiver chain frequency at a predefined frequency and set a transmitter chain frequency to be offset relative to the receiver chain frequency. For each of the amplifier gain steps, the state machine can set a gain of the receiver chain and set a power of the transmitter chain. The baseband processor can measure an RSSI and transmit the measured RSSI to the state machine. The state machine can determine a digital gain compensation value based on the one or more measured RSSIs and apply the determined digital gain compensation value.

Abstract: A self-calibrating transceiver includes a baseband processor, a receiver chain comprising an amplifier and a digital front end (DFE), and a transmitter chain, and a calibration control state machine. The state machine stores amplifier gain steps and is in communication with the transmitter chain, the receiver chain, and the baseband processor. The state machine can set a receiver chain frequency at a predefined frequency and set a transmitter chain frequency to be offset relative to the receiver chain frequency. For each of the amplifier gain steps, the state machine can set a gain of the receiver chain and set a power of the transmitter chain. The baseband processor can measure an RSSI and transmit the measured RSSI to the state machine. The state machine can determine a digital gain compensation value based on the one or more measured RSSIs and apply the determined digital gain compensation value.

Abstract: A self-calibrating transceiver includes a baseband processor, a receiver chain comprising an amplifier and a digital front end (DFE), and a transmitter chain, and a calibration control state machine. The state machine stores amplifier gain steps and is in communication with the transmitter chain, the receiver chain, and the baseband processor. The state machine can set a receiver chain frequency at a predefined frequency and set a transmitter chain frequency to be offset relative to the receiver chain frequency. For each of the amplifier gain steps, the state machine can set a gain of the receiver chain and set a power of the transmitter chain. The baseband processor can measure an RSSI and transmit the measured RSSI to the state machine. The state machine can determine a digital gain compensation value based on the one or more measured RSSIs and apply the determined digital gain compensation value.

Abstract: A self-calibrating transceiver includes a baseband processor, a receiver chain comprising an amplifier and a digital front end (DFE), and a transmitter chain, and a calibration control state machine. The state machine stores amplifier gain steps and is in communication with the transmitter chain, the receiver chain, and the baseband processor. The state machine can set a receiver chain frequency at a predefined frequency and set a transmitter chain frequency to be offset relative to the receiver chain frequency. For each of the amplifier gain steps, the state machine can set a gain of the receiver chain and set a power of the transmitter chain. The baseband processor can measure an RSSI and transmit the measured RSSI to the state machine. The state machine can determine a digital gain compensation value based on the one or more measured RSSIs and apply the determined digital gain compensation value.

Abstract: A self-calibrating transceiver includes a transmitter chain, a receiver chain, a base band processor, and a calibration control state machine. The state machine is in electrical communication with the transmitter chain, the receiver chain, and the base band processor, and is configured for enabling the receiver chain and setting the receiver chain and the transmitter chain to corresponding frequencies. The state machine stores one or more transmitter power and power amplifier gain mode settings, and for each setting, sets the transmitter gain and power amplifier gain mode. The transmitter chain transmits a signal, the receiver chain receives the transmitted signal, and the baseband processor measures a received signal strength indicator (RSSI) of the received signal. The state machine further adjusts the transmitter output power based on the measured RSSI.

Abstract: A foaming agent comprising an amount of soy whey protein is disclosed herein, the soy whey protein having been isolated from processing streams. The foaming agent is especially suitable for producing a food product.

Abstract: A foaming agent comprising an amount of soy whey protein is disclosed herein, the soy whey protein having been isolated from processing streams. The foaming agent is especially suitable for producing a personal care product or an industrial product.

Abstract: An emulsifying agent comprising an amount of soy whey protein is disclosed herein, the soy whey protein having been isolated from processing streams. The emulsifying agent is especially suitable for producing a food product.

Abstract: An emulsifying agent comprising an amount of soy whey protein is disclosed herein, the soy whey protein having been isolated from processing streams. The emulsifying agent is especially suitable for producing a personal care product or industrial product.

Abstract: The invention provides agents, compositions, pharmaceutical compositions and method for inhibiting tumor cell proliferation by inhibiting FoxM1B activity, expression, or nuclear localization in a tumor cell.

Abstract: The present invention provides soy based non-dairy compositions and the method for producing the soy based non-dairy compositions. In particular, the soy based non-dairy compositions comprise soy protein hydrolysate compositions in non-dairy coffee creamers.