Abstract: Provided is a mutant of CRISPR nuclease FnCpf1. Compared with wild-type FnCpf1, the CRISPR nuclease FnCpf1 has the following mutations: K671R/E566V/D751G/N508H/N637S, K671R/E566V/D751G/F570L/N634D/R755K, K671R/E566V/D751G/S518G/K639R, K671R/E566V/D751G/F570L/E686D, K671R/E566V/D751G/K613N/N637S/N534K/G664V, K671R/E566V/D751G/K613N/F570L/G664S/N637Y, K671R/E566V/D751G/K613N/Y724C/F570L, or K671R/E566V/D751G/K613N/Y724C/F570L/R690I/L662I. The coding gene of the mutant has higher editing efficiency and wider editing range than the wild-type FnCpf1.

Abstract: A scheduling system includes a receiving system and a transfer system. The receiving system receives a carrier carrying a biological sample. The transfer system transfers the sample carrier between biochemical reaction platform and detection platform, so that a sample in the sample carrier performs a biochemical reaction on the biochemical reaction platform, and a signal from the reacted sample can be detected on the detection platform. The present disclosure further provides a scheduling method, a scheduling control system, a biochemical analysis system and device, and a computer-readable storage medium. The present disclosure improves a degree of automation of sample carrier scheduling, and realizes simultaneous analysis of multiple sample carriers to improve a testing throughput.

Abstract: Provided is a method of producing an oil containing polyunsaturated fatty acids by using Schizochytrium sp. The method comprises: performing fermentation using Schizochytrium sp.; resuspending the resultant cells after fermentation in water, adding cellulase and neutral protease for enzymolysis; mixing the enzymatic hydrolyzate with n-hexane, shaking, extracting, centrifuging, and collecting the n-hexane phase; concentrating the n-hexane phase under reduced pressure to remove the n-hexane, and drying to obtain an oil; performing a first crystallization and a second crystallization, and then performing cold filtration to obtain a liquid oil after the second crystallization; and subjecting the liquid oil to deacidification and decolorization. By regulating fermentation conditions and conducting concentration processing on polyunsaturated fatty acids, the content of eicosapentaenoic acid in the Schizochytrium sp.

Abstract: Provided is a method of producing an oil containing polyunsaturated fatty acids by using Schizochytrium sp. The method comprises: performing fermentation using Schizochytrium sp.; resuspending the resultant cells after fermentation in water, adding cellulase and neutral protease for enzymolysis; mixing the enzymatic hydrolyzate with n-hexane, shaking, extracting, centrifuging, and collecting the n-hexane phase; concentrating the n-hexane phase under reduced pressure to remove the n-hexane, and drying to obtain an oil; performing a first crystallization and a second crystallization, and then performing cold filtration to obtain a liquid oil after the second crystallization; and subjecting the liquid oil to deacidification and decolorization. By regulating fermentation conditions and conducting concentration processing on polyunsaturated fatty acids, the content of eicosapentaenoic acid in the Schizochytrium sp.

Abstract: The present invention discloses a blood lipid-reducing composition, the active components of the composition are composed of fish oil, linseed oil, phytosterol ester or phytosterol. The composition mainly comprises components such as ?-linolenic acid, EPA, DHA and phytosterol or phytosterol ester, can reduce serum total cholesterol (TC), triglyceride (TG) and low-density lipoprotein cholesterol (LDL-C), has an efficacy of reducing blood lipid. The present invention also discloses the use of the blood lipid-reducing composition in the manufacture of health food having a function of reducing blood lipid.

Abstract: The present invention discloses a composition and use. The composition comprises hemp seed oil and algal oil with a mass ratio of (20˜60):(30˜70). After a large number of screening studies on concerted application, the present inventors found that the composition has synergistic effects, specifically, it has significant inhibitory effects on weight gain of animal model rats for hyperlipidemia, can significantly increase the hypolipidemic efficacy, and has an anti-oxidation effect. In addition, the composition of the present invention has efficacies of improving learning and memory abilities, improving constipation, and protecting the liver. Medicaments and functional food made from the composition of the present invention are simple in production process, stable in product quality, clear in functional factor, prominent in health care efficacy, low in administration dosage, safe in use, without toxic and side effects, and are suitable for consumption of the general population.

Abstract: A positive electrode comprising ?-VOPO4 and/or Nax(?-VOPO4) wherein x is a value from 0.1 to 1.0 as an active ingredient, wherein the electrode is capable of insertion and release of sodium ions and a reversible sodium battery containing the positive electrode are provided.

Abstract: The present invention discloses a composition and use. The composition comprises hemp seed oil and algal oil with a mass ratio of (20˜60):(30˜70). After a large number of screening studies on concerted application, the present inventors found that the composition has synergistic effects, specifically, it has significant inhibitory effects on weight gain of animal model rats for hyperlipidemia, can significantly increase the hypolipidemic efficacy, and has an anti-oxidation effect. In addition, the composition of the present invention has efficacies of improving learning and memory abilities, improving constipation, and protecting the liver. Medicaments and functional food made from the composition of the present invention are simple in production process, stable in product quality, clear in functional factor, prominent in health care efficacy, low in administration dosage, safe in use, without toxic and side effects, and are suitable for consumption of the general population.

Abstract: A positive electrode comprising ?-VOPO4 and/or Nax(?-VOPO4) wherein x is a value from 0.1 to 1.0 as an active ingredient, wherein the electrode is capable of insertion and release of sodium ions and a reversible sodium battery containing the positive electrode are provided.

Abstract: The present invention discloses a blood lipid-reducing composition, the active components of the composition are composed of fish oil, linseed oil, phytosterol ester or phytosterol. The composition mainly comprises components such as a-linolenic acid, EPA, DHA and phytosterol or phytosterol ester, can reduce serum total cholesterol (TC), triglyceride (TG) and low-density lipoprotein cholesterol (LDL-C), has an efficacy of reducing blood lipid. The present invention also discloses the use of the blood lipid-reducing composition in the manufacture of health food having a function of reducing blood lipid.

Abstract: A method for generating a lesson plan for a course is provided that includes associating a plurality of standard objectives with the course. A plurality of learning activities are provided for selection. Each learning activity is associated with at least one standard objective for the course. A selection of at least a subset of the learning activities is received. The lesson plan is generated based on the selected learning activities.

Abstract: A method for generating a lesson plan for a course is provided that includes associating a plurality of standard objectives with the course. A plurality of learning activities are provided for selection. Each learning activity is associated with at least one standard objective for the course. A selection of at least a subset of the learning activities is received. The lesson plan is generated based on the selected learning activities.

Abstract: A method for generating a lesson plan for a course is provided that includes associating a plurality of standard objectives with the course. A plurality of learning activities are provided for selection. Each learning activity is associated with at least one standard objective for the course. A selection of at least a subset of the learning activities is received. The lesson plan is generated based on the selected learning activities.

Abstract: A method and apparatus for controlling bit slips in a high-speed, two-way, communications channel. More particularly, the entire communications system, comprising, inter alia, a receiver, a transmitter and the physical communications channel is operated as a feedback loop. That is, the detection of bit slips is performed continuously in the receiver and a bit slip signal is generated that indicates the number of bit slips and the direction, i.e., forward or backward, of the bit slip. Thus, the bit slip signal is communicated to the transmitter and certain actions are performed to introduce bit adjustments in the bit stream to eliminate the effects of any future bit slips. The bit slip signal contains an indication of the number of bit slips which have occurred, the time between bit slips, and the direction of the slip. As a function of this information from the bit slip signal, bit adjustments are made in the communications stream to correct for the bit slips and mitigate any effect in future transmission.

Abstract: A method and apparatus for achieving maximum bandwidth reduction in communication networks. The invention provides a multisource coding scheme, implemented through an intersource coding block that provides maximum bandwidth reduction for transmissions from a plurality of time-correlated information sources over a single physical link. In one embodiment of the invention the intersource encoder uses run-length coding to compress the aggregate bit rate before the physical transmission. The intersource encoder provides data compression for both completely correlated and partially correlated sources. For completely correlated sources, the intersource encoder strips off the intersource redundancies and transmits only a single copy of the information over the physical link, wherein the single copy is a superpicture. For partially correlated sources, the intersource encoder compresses the aggregate signal through a predetermined coding scheme, including vector run-length coding.

Abstract: A method and apparatus for reducing bandwidth in an ATM network. The invention provides an ATM switch having a compression module for compressing ATM cell headers without affecting the virtual circuit established for the call. The compressed headers provide the ATM switch buffers with extra space to handle more cells for a given call. To realize the benefit of the extra space during transmission, the present invention provides a mapping interface between the PHY and ATM layers of the ATM communication. The mapping interface separates the compressed headers from the uncompressed headers into two different PHY payloads. The cells transmitted in the compressed payload are then expanded in an expansion module located in the call destination switch. The expansion module returns the compressed headers back to their original form.

Abstract: A digital communication system for transmitting and receiving a hybrid optical and RF communication signal. The system includes a hybrid transmitter that incorporates an optical transmitter, an RF transmitter, and a transmitter control unit that controls both transmitters. Similarly, a hybrid receiver includes an optical receiver and an RF receiver, both connected to a receiver control unit. When an optical carrier signal is transmitted to the optical receiver by the optical transmitter, the transmitter control unit causes the RF transmitter to transmit an RF synchronization signal along with the carrier to provide a timing base for the digital pulses carried by the optical signal. The receiver control unit uses the timing parameters from the RF signal to reconstruct the received optical carrier signal that may have deteriorated during the transmission due to ambient optical noise, attenuation or obstructing objects.

Abstract: A method and apparatus for implementation of a code division multiple access encoding scheme in a fiber-optic network. One preferred embodiment of the present invention provides an encoder and decoder for each terminal in the communications network, for example SONET OC-3, and allows each terminal to transmit their signals into the fiber-optic network at random. Because no time slot management is used, signals from all terminals interfere with one another. A coding technique is used by each decoder to sort its own signal out of this interference. The encoded data from each terminal is modulated with a technique known as MFSK (multiple frequency shift keying). The modulated signal is further used to intensity-modulate a semiconductor laser diode which may or may not be a single wavelength laser. At the receiver, the combined interference signal is first detected by a optical intensity detector and then sent to a frequency tone detectors which demodulate the MFSK signal.

Abstract: An optical communications system for transmission of optical signals using relaxation oscillation subcarrier, on-off keying modulation of the optical signals. Relaxation oscillation subcarrier on-off keying improves the signal-to-noise ratio of a receiver receiving the modulated optical signals and the data rate of the optical signal. A modulation device generates relaxation oscillations by pulsing a driving current for a transmitter between a first level below a threshold current and a second level above the threshold current. The optical communication system can further include a fiber optic link between the transmitter and the receiver. The optical communications system can further incorporate multiple frequency shift keying. The modulation device and modulation scheme can be used in all digital optical communications systems using a pulsed laser diode.

Abstract: Only one or only a few channels are sent at a time from curbside circuitry located in a curbside box, via a link such as either a coaxial or a fiber cable, into a customer's home TV set or personal computer. However, many more than a few channels are delivered to the curbside box from a central office or a central bank of paid video-movies to be selected by the customers. The curbside box serves a multitude of homes, a separate (narrow-band) cable running to each home from the (same) curbside switch. Each channel can be a free radio or free TV channel, a stored or an on-line newspaper pay channel, or a pay TV channel, or a pay-per-view channel. Requests from each TV set in each home (e.g., initiated by a hand-held remote control infra-red sending device) can be sent to the curbside circuitry from the home along a link such as a wire or along the same curbside-to-home cable itself. Storage of billing information with respect to each customer is accomplished by a billing recorder located in the curbside box.