Abstract: A novel method of preparation of easily stripped off temporary wound dressing material is disclosed. In this process, the-N-isopropyl acrylamide (NIPAAm) monomer is successfully grafted on the non-woven cloths by copolymerization. It is initiated by .gamma.-ray irradiation to activate the surface of the non-woven cloth. NIPAAm is then grafted onto the surface of the non-woven cloth. The free radical or peroxide is produced by Co-60 .gamma.-ray, then grafted on the non-woven cloths. The lower critical solution temperature (LCST) in thermoresponsive poly-N-isopropylacrylamide (NIPAAm) is still retained after the grafting. This will make the dressing cloth stripped off easily and without hurting the tissue. The material process is very simple and has medically applicable value.

Abstract: This invention is a novel synthesis of BCA-peptides (BCA: bifunctional chelating agents). In this method, the starting material--Fmoc-Thr(ol)-Terephthal-Acetal-Amide Resin is coupled with the various amino acids. The straight peptide-resin of D-Phe-Cys(Trt)-Phe-D-Trp(Boc)-Lys(Boc)-Thr(tBu)-Cys(Trt)-Thr(ol)-Terephtha l-Acetal-Amide Resin was obtained. This compound reacted with iodine to give disulfide-containing peptide resin of ##STR1## Cleavage of the peptide from the resin was achieved by TFA. The cleavaged peptide was protected by the reaction of octreotide with di-t-butyldicarbonate. BCA was coupled to the selectively protected octreotide. This product was obtained by reaction of protected BCA-peptides with TFA. The final product was labeled by radioisotope .sup.111 InCl.sub.3 for tumor imaging radiopharmaceuticals.

Abstract: Novel tumor imaging agents in which the dimercaptosuccinic acid was dissolved in phosphate buffer and labelled with radioisotope gallium. The product of gallium dimercaptosuccinate has been characterized by a variety of experiments including serum stability, biodistribution and imaging experiment. As the results, the compound of gallium dimercaptosuccinate has been confirmed as a novel radiopharmaceutical for tumor imaging agent.

Abstract: The invention relates to a method for synthesis of poly(L-leucine). Without any initiator and solvent poly(L-leucine) has been made from L-leucine-N-carboxy anhydride as starting material in the solid state by irradiation with gamma ray. There is only one step in the entire synthetic processing, and the polymerization yield is 100% and the process is a very simple, safe and convenient method. The poly(L-leucine) is one of the best materials for temporary wound dressing.