Patents by Inventor Zejun SUN

Zejun SUN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for preparing nanohybrid used for ratiometric fluorescence and ratiometric electrochemical sensing simultaneously
    Patent number: 11073517
    Abstract: A method for preparing a nanohybrid used for ratiometric fluorescence and ratiometric electrochemical sensing simultaneously is provided. Surface-aminated (—NH2) SiO2 nanospheres encapsulating an electroactive material A or B are prepared and conjugated with surface-carboxylated (—COOH) carbon dots (CDs) or gold nanoclusters (AuNCs) to prepare a conjugate, and the conjugate is conjugated with a DNA aptamer terminated with —NH2. Ions or biomolecules are added to two types of DNA-conjugate dispersions, and ratiometric florescence sensing is realized by fitting the linear relationship between ratiometric fluorescent peak intensity ICDs/IAuNCs and a specific ion concentration or a specific biomolecule concentration.
    Type: Grant
    Filed: April 3, 2019
    Date of Patent: July 27, 2021
    Assignee: QINGDAO UNIVERSITY
    Inventors: Hui Jin, Rijun Gui, Yujiao Sun, Xiaowen Jiang, Zejun Sun
  • METHOD FOR PREPARING NANOHYBRID USED FOR RATIOMETRIC FLUORESCENCE AND RATIOMETRIC ELECTROCHEMICAL SENSING SIMULTANEOUSLY
    Publication number: 20210222063
    Abstract: A method for preparing a nanohybrid used for ratiometric fluorescence and ratiometric electrochemical sensing simultaneously is provided. Surface-aminated (—NH2) SiO2 nanospheres encapsulating an electroactive material A or B are prepared and conjugated with surface-carboxylated (—COOH) carbon dots (CDs) or gold nanoclusters (AuNCs) to prepare a conjugate, and the conjugate is conjugated with a DNA aptamer terminated with —NH2. Ions or biomolecules are added to two types of DNA-conjugate dispersions, and ratiometric florescence sensing is realized by fitting the linear relationship between ratiometric fluorescent peak intensity IcDs/IAuNcs and a specific ion concentration or a specific biomolecule concentration.
    Type: Application
    Filed: April 3, 2019
    Publication date: July 22, 2021
    Applicant: QINGDAO UNIVERSITY
    Inventors: Hui JIN, Rijun GUI, Yujiao SUN, Xiaowen JIANG, Zejun SUN