Abstract: The present disclosure provides an arctigenin liquid nano-preparation and a preparation method thereof, and relates to the technical field of pharmaceutical preparation. In the present disclosure, arctigenin is prepared into a liquid nano-preparation, having advantages of distribution of a droplet diameter on nanoscale, significantly increased specific surface area, rapid absorption, and high bioavailability. Meanwhile, nano-preparation entered the body can be captured by wandering leucocytes, and a medicament is delivered to inflammatory lesions through chemiotaxis, thereby conferring a targeted drug delivery feature on the arctigenin and making a therapy more targeted. Moreover, in the present disclosure, the arctigenin is dissolved in an oil phase, and the oil phase is dissolved in water by emulsification to further make the arctigenin dissolve in the water and increase water solubility of the arctigenin.

Abstract: Provided herein are methods for regenerating hair cells in an adult mammalian inner ear using novel combinations of agents selected from the group consisting of a histone deacetylase (HDAC) inhibitor, one or more inhibitory nucleic acids targeting Fir, Mxi1, Fbxw7, or a combination thereof, a Wnt pathway activator, and a cAMP activator. The methods and compositions can be used to treat a subject with hearing loss or vestibular dysfunction.

Abstract: An ear cartilage tissue engineering complex and a preparation method therefor are provided. The complex includes an ear cartilage gel or ear cartilage patch particles containing ear cartilage cells, and a porous frame structure. The ear cartilage gel or ear cartilage patch particles are inoculated onto the porous frame structure to form an ear cartilage gel/ear cartilage patch particle-frame structure complex. The ear cartilage tissue engineering complex is used for the repair and reconstruction of articular cartilage.

Abstract: A cartilage tissue engineering complex, e.g., a graft, has a cartilage gel or perichondral particles containing chondrocytes as well as a porous frame structure. The cartilage gel or perichondral particles is/are loaded on the porous frame structure to form a cartilage gel/perichondral particle-frame structure complex. The method for preparing the cartilage tissue engineering graft and a use of said graft in repair and reconstruction of articular cartilage are also provided.

Abstract: The present disclosure relates to a spike event decision-making device, method, chip, and electronic device to eliminate inherent delays of an output spike event of the neuromorphic chip when reading decisions. The spike event decision-making device includes a first counting module configured to count a number of input spike events of the spiking neural network, a second counting module configured to count some or all of the output spike events of the spiking neural network; and a decision-making module configured to generate a decision-making result according to numbers of spike events fired by neurons in an output layer of the spiking neural network when the number counted by the first counting module reaches a first predetermined value, or when the total count counted by the second counting module reaches a second predetermined value.

Abstract: The present disclosure is directed to an antenna array. The antenna array includes a plurality of dielectric windows coupled to a support structure comprising a plurality of gas ports, a primary frame comprising a primary conduit connected to a power source and a plurality of secondary frames supported by the primary frame. The secondary frame includes a secondary conduit connected to the primary conduit. A plurality of inductive couplers are disposed over the plurality of dielectric windows and supported by the secondary frames. The plurality of inductive couplers include a plurality of antenna connectors and a plurality of plurality of antennas. The plurality of antenna connectors connect the plurality of antennas to the secondary conduit.

Abstract: The invention provides a reaction system for preparing butyraldehyde by propylene carbonylation, comprising: a reactor; a side wall of the reactor is sequentially provided with a catalyst inlet, a propylene inlet and a synthesis gas inlet from top to bottom; the bottom of the reactor is provided with a solvent inlet; two micro-interface generators are arranged inside of the reactor from top to bottom, and the micro-interface generator located at a top end is connected to the propylene inlet to break the propylene gas into micron-scale micro-bubbles; the micro-interface generator located at a bottom is connected to the synthesis gas inlet for breaking the synthesis gas into micron-scale micro-bubbles; the outlets of the two micro-interface generators are opposite, and the outlets are connected with a gas distributor for evenly distributing raw materials.

Abstract: A full-face shaft tunnel boring machine system includes a tunnel boring machine cutterhead device for tunneling downwards in a shaft; a full-hydraulic formwork device for supporting and walling in a wellbore; and an upper muck-discharge system for vertically conveying rock mucks generated by tunneling. The tunnel boring machine cutterhead device comprises a vertical guide frame, a cutter-expanded boring head and an advanced cutterhead that are fixedly connected in a vertical order from top to bottom so as to form an integrated structure. The vertical guide frame is a hollow cylindrical structure and driven to rotate around an axis of the vertical guide frame by a power mechanism, and an outer wall of the vertical guide frame is provided with multiple sets of first guide rollers.

Abstract: Disclosed are a fault diagnosis circuit, method and apparatus, and computer readable storage medium. The fault diagnosis circuit includes a safety protection circuit electrically connected to a protected circuit and a diagnosis module electrically connected to the safety protection circuit. The safety protection circuit is configured to perform check operation on stored data in the protected circuit to obtain first check data, perform error injection on second check data corresponding to the stored data, and generate a first check result signal based on the first check data and the second check data after the error injection. The diagnosis module is configured to diagnose faults in the safety protection circuit based on the first check result signal. From embodiments of this disclosure, the safety protection circuit is diagnosed faults through a simple hardware structure, to eliminate the faults based on a diagnosis result, thereby ensuring normal operation of a chip.

Abstract: An air conditioning device is provided. The device has a fresh air component and a control valve assembly. The fresh air component has a housing assembly and an air treatment assembly. The housing assembly has a ventilation cavity, a fresh air cavity and an exhaust cavity. The air treatment assembly is disposed in the exhaust cavity. The control valve assembly has a first valve assembly and a second valve assembly, which are independent of each other. An outlet of the ventilation cavity is in communication with an indoor space through the exhaust cavity and an air outlet when the first valve assembly is in an open state. The outlet of the ventilation cavity is in communication with the fresh air cavity when the second valve assembly is in an open state.

Abstract: A display system includes a display module, a projection component, and a projection bearing component. The projection component is disposed with respect to a display side defined by a second liquid crystal panel. The projection bearing component is disposed with respect to a side of the projection component away from the display module. The projection component is configured to project a display image of the second liquid crystal panel onto the projection bearing component.

Abstract: The present invention relates generally to nucleic acid molecules in respect of which changes to DNA methylation levels are indicative of the onset or predisposition to die onset of a neoplasm. More particularly, the present invention is directed to nucleic acid molecules in respect of which changes to DNA methylation levels are indicative of the onset and/or progression of a large intestine neoplasm, such as an adenoma or adenocarcinoma. The DNA methylation status of the present invention is useful in a range of applications including, but not limited to, those relating to the diagnosis and/or monitoring of colorectal neoplasms, such as colorectal adenocarcinomas. Accordingly, in a related aspect the present invention is directed to a method of screening for the onset, predisposition to the onset and/or progression of a neoplasm by screening for modulation in DNA methylation of one or more nucleic acid molecules.

Abstract: The present application provides a display panel and an electronic device. The electronic device includes a display panel. The display panel includes a backlight module. The backlight module includes a frame, an optical film group, and a fixing block. Movements of the optical film group can be limited in a thickness direction of the display panel by pressing the fixing block on the optical film group. Therefore, optical films can be fixed, so problems of abnormal noise, displacement, and scratches of the optical films in the display panel adopting a direct-lit mini light-emitting diode (LED) light source are prevented.

Abstract: The invention provides a reaction system for preparing butyraldehyde by propylene carbonylation, comprising: a reactor; a side wall of the reactor is sequentially provided with a catalyst inlet, a propylene inlet and a synthesis gas inlet from top to bottom; the bottom of the reactor is provided with a solvent inlet; two micro-interface generators are arranged inside of the reactor from top to bottom, and the micro-interface generator located at a top end is connected to the propylene inlet to break the propylene gas into micron-scale micro-bubbles; the micro-interface generator located at a bottom is connected to the synthesis gas inlet for breaking the synthesis gas into micron-scale micro-bubbles; the outlets of the two micro-interface generators are opposite, and the outlets are connected with a gas distributor for evenly distributing raw materials.

Abstract: In one embodiment, a method includes, by one or more computing systems, receiving, from a client system via an assistant xbot, a first audio input from a user, parsing the first audio input to identify a request for a content digest from an online social network, retrieving a plurality of content objects from the online social network, each of the content objects being accessible by the user, generating a customized newsfeed summary based on a determined semantical meaning of each of the plurality of content objects, and sending, to the client system via the assistant xbot, instructions for presenting an audio clip to the user responsive to the request for the content digest, wherein the audio clip comprises the customized newsfeed summary.

Abstract: A vehicle-mounted display panel and a vehicle device are provided. The vehicle-mounted display panel includes a backplate, a first display panel, and a second display panel. A first groove and a second groove are respectively defined on two opposite sides of the backplate. The first display panel and the second display panel are respectively mounted in the first groove and the second groove to improve integration of the first display panel and the second display panel, which is conducive to saving mounting space and realizes lightweight design of vehicles.

Abstract: A backlight module and a display panel are provided. The backlight module includes a first engagement structure and a second engagement structure. By engaging the first engagement structure with the second engagement structure, a sealant and a bottom frame are fixed to each other to fix an optical film, thereby preventing the optical film from shifting and vibration scratches. Therefore, it is prevented to provide a positioning post for fixing the optical film on the light guide plate, and the applicability of a thermal-pressing process of the light guide plate is improved.

Abstract: A map update method and apparatus, and a map-based driving decision-making method and apparatus are provided and applied to a vehicle. The map update method includes: obtaining tile update information of a map, where the tile update information indicates a changed tile of the map; determining a to-be-updated tile based on a pinpointed location of the vehicle, a navigation path of the vehicle, and the tile update information, where the to-be-updated tile is a part of tiles in the changed tile; downloading the to-be-updated tile from a server; updating the map based on the downloaded to-be-updated tile; and performing driving decision-making based on the updated map.