Abstract: Example methods and apparatus for processing a push message are described. One example method includes generating a first profile identifier based on an account identifier of a currently logged-in account of an app. The first profile identifier and a token in a push system are sent to a server of the app. A push message from the server is received by using a push connection corresponding to the token, where the push message includes a second profile identifier. A processing manner of the push message is determined based on whether the second profile identifier matches the first profile identifier. The first profile identifier is locally stored information generated by a terminal device.

Abstract: Provided is a urate oxidase preparation. The urate oxidase preparation includes polyethylene glycol-modified urate oxidase as an active ingredient and a buffer reagent as an excipient.

Abstract: Provided is a method for preparing a polyethylene glycol-modified urate oxidase, at least 11 of the following amino acid sites of the polyethylene glycol-modified urate oxidase have a PEG modification: T1, K3, K4, K30, K35, K76, K79, K97, K112, K116, K120, K152, K179, K222, K231, K266, K272, K285, K291, and K293, and the preparation method includes: performing a coupling reaction between urate oxidase and polyethylene glycol, wherein the polyethylene glycol is provided in the form of an acidic solution, and a molar ratio of the urate oxidase to the polyethylene glycol is 1: (56 to 94), to obtain the polyethylene glycol-modified urate oxidase.

Abstract: A communication device, method, and computer program product prompt correct face/eye positioning to enable perceived eye-to-eye contact of a user of a video capturing device with camera on a same device side as the viewable display device. A first communication device includes a first display device having a first graphical user interface (GUI). A first image capturing device of the first communication device has a field of view that captures a face of a first user viewing the first GUI. The first image capturing device generates a first image stream of the field of view. A controller of the communication device identifies a look target area of the first GUI proximate to the first image capturing device. The controller presents visual content on the first GUI within the look target area to prompt the first user viewing the first GUI to look towards the look target area.

Abstract: A hybrid method of low light image enhancement in an electronic device comprises downsampling a high resolution, low light image to obtain a low resolution, low light image and inputting the low resolution, low light image into a low light enhancement model of a deep neural network to obtain a low resolution, enhanced image where semantic information such as true colors, edges, and brightness level are recovered. The high resolution, low light image, the low resolution, low light image, and the low resolution, enhanced image are each input into a mathematical model that performs upsampling and super-resolution tasks to generate a high resolution, enhanced image.

Abstract: A communication device, method, and computer program product prompt correct face/eye positioning to enable perceived eye-to-eye contact of a user of a video capturing device with camera on a same device side as the viewable display device. A first communication device includes a first display device having a first graphical user interface (GUI). A first image capturing device of the first communication device has a field of view that captures a face of a first user viewing the first GUI. The first image capturing device generates a first image stream of the field of view. A controller of the communication device identifies a look target area of the first GUI proximate to the first image capturing device. The controller presents visual content on the first GUI within the look target area to prompt the first user viewing the first GUI to look towards the look target area.

Abstract: The present disclosure provides a polyethylene glycol-modified urate oxidase. At least 11 of the following amino acid sites in the urate oxidase have a PEG modification: T1, K3, K4, K30, K35, K76, K79, K97, K112, K116, K120, K152, K179, K222, K231, K266, K272, K285, K291, and K293.

Abstract: The present disclosure relates to HAPLN1 protein of an aged individual. The HAPLN1 protein exhibits reduced expression with aging, and when administered, its effect in alleviating and reversing skin aging including wrinkles is excellent. Therefore, by exploiting the difference in expression, provided are a biomarker composition for measuring skin aging, capable of diagnosing skin aging; a kit; and a method of screening for skin aging alleviating agents, comprising detecting the expression level of HAPLN1 protein or HAPLN1 gene. In addition, provided are a pharmaceutical composition, cosmetic composition, or health functional food for preventing or alleviating skin aging, and a cosmetic composition or health functional food for alleviating wrinkles, each containing any one or more selected from the group consisting of HAPLN1 protein, a gene encoding the same, and an effective agent for promoting the expression or activating the functions of HAPLN1 protein or gene.

Abstract: The present disclosure relates to HAPLN1 protein of an aged individual. The HAPLN1 protein exhibits reduced expression with aging, and when administered, its effect in alleviating and reversing skin aging including wrinkles is excellent. Therefore, by exploiting the difference in expression, provided are a biomarker composition for measuring skin aging, capable of diagnosing skin aging; a kit; and a method of screening for skin aging alleviating agents, comprising detecting the expression level of HAPLN1 protein or HAPLN1 gene. In addition, provided are a pharmaceutical composition, cosmetic composition, or health functional food for preventing or alleviating skin aging, and a cosmetic composition or health functional food for alleviating wrinkles, each containing any one or more selected from the group consisting of HAPLN1 protein, a gene encoding the same, and an effective agent for promoting the expression or activating the functions of HAPLN1 protein or gene.