Patents by Inventor Zhong-Jia Tan

Zhong-Jia Tan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Sequence and method for genetic engineering of proteins with cell membrane translocating activity
    Patent number: 6248558
    Abstract: The invention describes a membrane-translocating peptide sequence (MTS) which facilitates entry of polypeptides and proteins into cells. Also described is an isolated nucleotide sequence encoding the membrane-translocating peptide and a method of using this sequence to genetically engineer proteins with cell membrane permeability. The MTS, and the method of genetically engineering proteins with cell membrane permeability, are useful for polypeptide and protein delivery for human and veterinary applications such as vaccine delivery and cancer therapy.
    Type: Grant
    Filed: November 4, 1998
    Date of Patent: June 19, 2001
    Assignee: Vanderbilt University
    Inventors: Yao-Zhong Lin, John P. Donahue, Mauricio Rojas, Zhong-Jia Tan