Abstract: The present invention belongs to the technical field of medical instruments, and discloses a multifunctional compound light penetration enhanced imaging system and an enhanced imaging method. The structural design of the present invention is reasonable. Through the cooperation of the first working channel tube, the second working channel tube, and the third working channel tube, the size of the channel is switched. When the system shrinks to the minimum, the opening size of the wound is only ? of that when the system is fully opened, which is suitable for a double-channel spinal endoscopic surgery. When the system is expanded to the maximum, it is suitable for transforaminal endoscopic surgery, and is suitable for multiple surgical modes. By adding a special red light component on the basis of the white light to form compound light illumination and increase the system transmittivity, the background penetration is realized.

Abstract: The present invention belongs to the technical field of medical instruments, and discloses a multifunctional compound light penetration enhanced imaging system and an enhanced imaging method. The structural design of the present invention is reasonable. Through the cooperation of the first working channel tube, the second working channel tube, and the third working channel tube, the size of the channel is switched. When the system shrinks to the minimum, the opening size of the wound is only 1/3 of that when the system is fully opened, which is suitable for a double-channel spinal endoscopic surgery. When the system is expanded to the maximum, it is suitable for transforaminal endoscopic surgery, and is suitable for multiple surgical modes. By adding a special red light component on the basis of the white light to form compound light illumination and increase the system transmittivity, the background penetration is realized.

Abstract: The present invention discloses a gene delivery system containing a reduction-sensitive shielding system having a targeting function, a preparation method and an application in the field of gene therapy thereof. The gene delivery system is composed of a reduction-sensitive shielding system having a targeting function, cationic polymer material and plasmid DNA; the cationic polymer material and the plasmid DNA complexed to form complex particles, the reduction-sensitive shielding system having a targeting function is shielded on the complex surface by means of electrostatic interaction, so as to reduce the toxicity of the delivery system and successfully transfer the loaded genetic material into cells, thereby achieving expression of genetic material and completing the transfection process, and moreover, improving the targeting and the efficiency of gene transfection.

Abstract: The present invention discloses a gene delivery system containing a reduction-sensitive shielding system having a targeting function, a preparation method and an application in the field of gene therapy thereof. The gene delivery system is composed of a reduction-sensitive shielding system having a targeting function, cationic polymer material and plasmid DNA; the cationic polymer material and the plasmid DNA complexed to form complex particles, the reduction-sensitive shielding system having a targeting function is shielded on the complex surface by means of electrostatic interaction, so as to reduce the toxicity of the delivery system and successfully transfer the loaded genetic material into cells, thereby achieving expression of genetic material and completing the transfection process, and moreover, improving the targeting and the efficiency of gene transfection.