Patents by Inventor ZHUANG CHEN

ZHUANG CHEN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11959075
    Abstract: The present invention generally relates to systems and methods for imaging or determining nucleic acids, for instance, within cells. In some embodiments, the transcriptome of a cell may be determined. Certain embodiments are directed to determining nucleic acids, such as mRNA, within cells at relatively high resolutions. In some embodiments, a plurality of nucleic acid probes may be applied to a sample, and their binding within the sample determined, e.g., using fluorescence, to determine locations of the nucleic acid probes within the sample. In some embodiments, codewords may be based on the binding of the plurality of nucleic acid probes, and in some cases, the codewords may define an error-correcting code to reduce or prevent misidentification of the nucleic acids. In certain cases, a relatively large number of different targets may be identified using a relatively small number of labels, e.g., by using various combinatorial approaches.
    Type: Grant
    Filed: March 16, 2023
    Date of Patent: April 16, 2024
    Assignee: President and Fellows of Harvard College
    Inventors: Xiaowei Zhuang, Kok-Hao Chen, Alistair Boettiger, Jeffrey R. Moffitt, Siyuan Wang
  • Publication number: 20240121161
    Abstract: Disclosed are a network optimization method and apparatus, an electronic device, and a storage medium. The network optimization method may include: sending data analytics request information to a core network; receiving data analytics response information fed back by the core network and determining a model processing result according to an artificial intelligence learning model; and performing a network optimization operation according to the model processing result.
    Type: Application
    Filed: June 14, 2022
    Publication date: April 11, 2024
    Applicant: ZTE Corporation
    Inventors: Jiajun Chen, Yin Gao, Zhuang Liu, Dapeng Li
  • Publication number: 20240108784
    Abstract: A hydrogel for cell-laden bioprinting, bioink, and a preparation method and an application thereof, relates to the technical field of biomedical polymer hydrogels. The hydrogel for cell-laden bioprinting is polymer gel formed by adding a cell-specific material into a matrix of alginate and gelatin and crosslinking and curing, wherein the cell-specific material is polypeptide selected according to different laden cells. The structures printed using the hydrogel may have the advantages such as adjustable mechanical properties, adjustable porosity, high biocompatibility, high printing accuracy, and high customizability, which may widely support the printing of human tissues and organs such as spinal cord, cartilage, and heart, and has good prospects for applications in tissue repair, organ transplantation and so on.
    Type: Application
    Filed: December 15, 2022
    Publication date: April 4, 2024
    Applicants: SHANDONG UNIVERSITY, YANSHAN UNIVERSITY
    Inventors: Chuanzhen HUANG, Zhuang CHEN, Hanlian LIU, Peng YAO, Zhenyu SHI, Dun LIU, Hongtao ZHU, Bin ZOU, Zhen WANG, Minting WANG, Longhua XU, Shuiquan HUANG, Meina QU, Zhengkai XU, Yabin GUAN
  • Publication number: 20240114402
    Abstract: Provided are a handover method, a handover device, and a network system. The handover method includes: receiving cell information of a second cell sent by a second network element, wherein the second cell is a cell managed by the second network element, and the cell information includes predicted cell load information of the second cell; and sending a handover instruction to a terminal in a case where the cell information satisfies a preset condition, wherein the handover instruction is used for instructing the terminal to perform handover to the second cell, and the case where the cell information satisfies the preset condition at least indicates that the predicted cell load information of the second cell is lower than a configured first threshold.
    Type: Application
    Filed: November 2, 2020
    Publication date: April 4, 2024
    Inventors: Zhuang LIU, Yin GAO, Jiren HAN, Jiajun CHEN
  • Publication number: 20240073502
    Abstract: A camera module comprises a supporting member for supporting a sensor chip to move relative to a lens for correcting camera shake, a plurality of bulges is provided between the supporting member and a bottom plate. The bulges provide a reduced resistance to sliding on the supporting member. An electronic device using the module is also disclosed.
    Type: Application
    Filed: November 2, 2022
    Publication date: February 29, 2024
    Inventors: ZHUANG-ZHUANG JING, SHIN-WEN CHEN, JING-WEI LI, SHUAI-PENG LI, CONG CAO
  • Publication number: 20230091013
    Abstract: The present disclosure provides a preparation method of a catalyst slurry for a fuel cell membrane electrode assembly (MEA), including the following steps: preparing a slurry mixture with a catalyst, a dispersing solvent, an ionomer, a thickener, and a surfactant according to a certain mass ratio; subjecting the slurry mixture to pre-dispersion several times in an ultrasonic disperser and a high-shear emulsifying machine successively, to obtain a slurry pre-dispersion; and conducting dispersion on the slurry pre-dispersion in a high-pressure homogenizer to obtain the catalyst slurry. In the present disclosure, components of the catalyst slurry and a dispersion process are optimized and innovated, to construct a more effective three-phase interface. The MEA prepared according to the present disclosure has a significantly improved performance and reduced slurrying time; and is thus suitable for mass production.
    Type: Application
    Filed: September 9, 2022
    Publication date: March 23, 2023
    Inventors: JIAPING XIE, WEI ZHU, CHUANHE ZHU, ZHUANG CHEN, YINGCHAO SHANG, JUN SHEN
  • Patent number: 10826211
    Abstract: A card edge connector with an insulative housing includes opposite longitudinal side walls along a longitudinal direction with a receiving slot therebetween in a transverse direction. Each side wall forms a plurality of passageways. A plurality of contacts are respectively received within the corresponding passageways. Each contact includes a retaining section, a contacting section extending from the retaining section into the receiving slot, and a leg extending downwardly from the retaining section out of the housing. Each contact is further equipped with an auxiliary spring beam with an additional contacting section extending into the receiving slot. The contacts are initially linked to a single contact carrier strip so as to be simultaneously inserted into the corresponding passageways, respectively.
    Type: Grant
    Filed: January 28, 2019
    Date of Patent: November 3, 2020
    Assignees: FOXCONN (KUNSHAN) COMPUTER CONNECTOR CO., LTD., FOXCONN INTERCONNECT TECHNOLOGY LIMITED
    Inventors: Xin-Wei Wang, Guo-Xiang Niu, Zhuang Chen
  • Publication number: 20190237884
    Abstract: A card edge connector with an insulative housing includes opposite longitudinal side walls along a longitudinal direction with a receiving slot therebetween in a transverse direction. Each side wall forms a plurality of passageways. A plurality of contacts are respectively received within the corresponding passageways. Each contact includes a retaining section, a contacting section extending from the retaining section into the receiving slot, and a leg extending downwardly from the retaining section out of the housing. Each contact is further equipped with an auxiliary spring beam with an additional contacting section extending into the receiving slot. The contacts are initially linked to a single contact carrier strip so as to be simultaneously inserted into the corresponding passageways, respectively.
    Type: Application
    Filed: January 28, 2019
    Publication date: August 1, 2019
    Inventors: XIN-WEI WANG, GUO-XIANG NIU, ZHUANG CHEN
  • Patent number: 10224653
    Abstract: An electrical card edge connector for receiving an electronic card with a bottom notch therein, includes an insulative housing, a plurality of terminals and an alignment key. The housing includes two opposite side walls, a bottom wall and a central slot among the side walls and the bottom wall. The terminals are disposed in the corresponding side walls and extend into the central slot for mating with the electronic card. The alignment key includes a body received within the central slot, a pair of extension sections covering the two side walls, and a pair of securing sections attached to the bottom wall wherein the body is adapted to be received within the bottom notch of the electronic card.
    Type: Grant
    Filed: September 27, 2017
    Date of Patent: March 5, 2019
    Assignee: FOXCONN INTERCONNECT TECHNOLOGY LIMITED
    Inventors: Guo-Xiang Niu, Jian Zhang, Xin-Wei Wang, Zhuang Chen
  • Publication number: 20180090864
    Abstract: An electrical card edge connector for receiving an electronic card with a bottom notch therein, includes an insulative housing, a plurality of terminals and an alignment key. The housing includes two opposite side walls, a bottom wall and a central slot among the side walls and the bottom wall. The terminals are disposed in the corresponding side walls and extend into the central slot for mating with the electronic card. The alignment key includes a body received within the central slot, a pair of extension sections covering the two side walls, and a pair of securing sections attached to the bottom wall wherein the body is adapted to be received within the bottom notch of the electronic card.
    Type: Application
    Filed: September 27, 2017
    Publication date: March 29, 2018
    Inventors: GUO-XIANG NIU, JIAN ZHANG, XIN-WEI WANG, ZHUANG CHEN
  • Patent number: 9684582
    Abstract: An automatic analysis method for operation sequence and a system thereof are disclosed. The method comprising: receiving at least one operation sequence containing at least one operation record, the operation record including an operation of switching from a previous user interface to a post user interface, an interval time of switching from the previous user interface to the post user interface; forming time-dependent operation record groups of respective operation sequences based on the interval time and a first time threshold, wherein the time-dependent operation record group includes operation records whose interval time is less than the first time threshold; comparing time-dependent operation record groups of respective operation sequences to obtain identical time-dependent operation record groups; and calculating a frequency that identical time-dependent operation record groups occur in the operation sequence to obtain the identical time-dependent operation record groups having high frequency.
    Type: Grant
    Filed: January 14, 2014
    Date of Patent: June 20, 2017
    Assignee: International Business Machines Corporation
    Inventors: Zhuang Chen, Jia Fei, Wei Huang, Tao Kang, Yang Liu, Xiao Wen Zhu
  • Publication number: 20140214837
    Abstract: An automatic analysis method for operation sequence and a system thereof are disclosed. The method comprising: receiving at least one operation sequence containing at least one operation record, the operation record including an operation of switching from a previous user interface to a post user interface, an interval time of switching from the previous user interface to the post user interface; forming time-dependent operation record groups of respective operation sequences based on the interval time and a first time threshold, wherein the time-dependent operation record group includes operation records whose interval time is less than the first time threshold; comparing time-dependent operation record groups of respective operation sequences to obtain identical time-dependent operation record groups; and calculating a frequency that identical time-dependent operation record groups occur in the operation sequence to obtain the identical time-dependent operation record groups having high frequency.
    Type: Application
    Filed: January 14, 2014
    Publication date: July 31, 2014
    Applicant: INTERNATIONAL BUSINESS MACHINES CORPORATION
    Inventors: ZHUANG CHEN, JIA FEI, WEI HUANG, TAO KANG, YANG LIU, XIAO WEN ZHU